Chronic Kidney Disease

Infection Risk Increases as Kidney Function Declines

Infection Risk Increases as Kidney Function Declines

Lower respiratory tract infections, urinary tract infections, and sepsis made up a larger proportion of infections as kidney function worsened.

CKD May Be a Risk Factor for NMIBC Recurrence, Progression

CKD May Be a Risk Factor for NMIBC Recurrence, Progression

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Stage G3b-5 chronic kidney disease independently predicted a nearly 2-fold increased risk recurrence and 3-fold increased risk of progression following transurethral resection.

Glomerular Disease Differs Globally

Glomerular Disease Differs Globally

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International survey finds geographic variation in the subtype frequencies in biopsied patients.

Decreasing Kidney Function Increases Atrial Fibrillation Risk

Decreasing Kidney Function Increases Atrial Fibrillation Risk

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Atrial fibrillation risk increases as estimated glomerular filtration rate decreases and albuminuria increases, according to a new meta-analysis.

Olfactory Deficits, Malnutrition Markers Linked in CKD, ESRD Patients

Olfactory Deficits, Malnutrition Markers Linked in CKD, ESRD Patients

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Pilot study suggests intranasal theophylline may be worth further investigation as a treatment.

Methylprednisolone Tied With Serious Adverse Events in IgA Nephropathy

Methylprednisolone Tied With Serious Adverse Events in IgA Nephropathy

The researchers found that serious events occurred in 14.7% and 3.2% of participants in the methylprednisolone and placebo groups, respectively, mainly due to excess serious infections.

Proteomics Identifies CKD Predictors

Proteomics Identifies CKD Predictors

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The investigators assessed proteomic profiling of 80 proteins using a multiplex assay.

Increased Mortality in CKD Pts With Impaired LV Global Longitudinal Strain

Increased Mortality in CKD Pts With Impaired LV Global Longitudinal Strain

After adjustment for age, gender, albumin levels, atrial fibrillation, and renal transplantation, LV GLS ≤10.6% was significantly associated with increased risk of all-cause mortality.

Low Hemoglobin, Low SEVR Linked in Chronic Kidney Disease

Low Hemoglobin, Low SEVR Linked in Chronic Kidney Disease

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Researchers used pulse wave analysis to measure subendocardial viability ratio, a measure of myocardial perfusion, and its association with hemoglobin.

suPAR May Trigger CKD, Renal Decline in <i>APOL1</i> Variant Pts

suPAR May Trigger CKD, Renal Decline in APOL1 Variant Pts

The team found that elevated levels of the suPAR protein triggered the start and progression of chronic kidney disease in those with 2 copies of APOL1 gene variants.

Intensive Blood Pressure Reduction Benefits CKD Patients

Intensive Blood Pressure Reduction Benefits CKD Patients

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CKD patients treated to a target systolic blood pressure of less than 120 mm Hg were 28% less likely to die early.

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

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Anemic patients were 41% and 80% more likely to have coronary artery disease and peripheral artery disease than non-anemic patients.

CKD Linked to High Intake of Red, Processed Meat

CKD Linked to High Intake of Red, Processed Meat

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Chronic kidney disease stage 3 is 23% more likely to develop in individuals in the highest versus lowest quintile of consumption of red and processed meat.

1 in 7 Americans Has CKD and Most Unaware

1 in 7 Americans Has CKD and Most Unaware

The researchers said rising rates of diabetes and hypertension may help explain the increase in kidney disease, along with several other factors.

Nephrology Referrals May Not Benefit Elderly CKD Patients

Nephrology Referrals May Not Benefit Elderly CKD Patients

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Most elderly CKD patients ultimately will not require or desire renal replacement therapy.

High-Dose Vitamin D May Halt Secondary Hyperparathyroidism Progression

High-Dose Vitamin D May Halt Secondary Hyperparathyroidism Progression

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In a study of CKD patients, intact PTH levels remained stable those receiving cholecalciferol 8000 IU daily but increased in placebo recipients.

Biomarker May Identify High-risk IgAN Patients

Biomarker May Identify High-risk IgAN Patients

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Gd-IgA1 level may represent a useful biomarker for risk stratification.

Afib Patients With CKD on NOACs May Be Overdosed

Afib Patients With CKD on NOACs May Be Overdosed

The incorrect dose was associated with a higher risk of major bleeding but no significant difference in stroke prevention, the researchers said.

Model Predicts Acute GI Bleeding With Oral Anticoagulant Tx

Model Predicts Acute GI Bleeding With Oral Anticoagulant Tx

GI bleeding was predicted by absence of PPI therapy, CKD, COPD, history of peptic ulcer disease, and liver cirrhosis.

Novel Enteric Budesonide Reduces Proteinuria in IgAN

Novel Enteric Budesonide Reduces Proteinuria in IgAN

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Overall, patients receiving TRF-budesonide saw a 24.4% reduction in their average urine protein creatinine ratio over 9 months.

Coffee Consumption Does Not Worsen ADPKD

Coffee Consumption Does Not Worsen ADPKD

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Coffee drinkers did not have a statistically significant difference in kidney size or estimated glomerular filtration rate compared with those who did not drink coffee.

New Review Highlights Iron Deficiency Anemia in CKD

New Review Highlights Iron Deficiency Anemia in CKD

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Intravenous iron should be strongly considered for patients treated with ESAs or hemodialysis, according to reviewers.

Anthropometric Body Fat Measurements Can Estimate Renal Function Decline

Anthropometric Body Fat Measurements Can Estimate Renal Function Decline

The researchers found that 17% of the population experienced KF decline, while incident CKD occurred in 17% of those at risk.

Hospital-Acquired Complications Can Be Deadly for CKD Patients

Hospital-Acquired Complications Can Be Deadly for CKD Patients

Preventable HACs are associated with higher mortality, incremental LOS, and greater risk of readmission, especially in people with CKD.

Testosterone Replacement May Delay CKD Progression

Testosterone Replacement May Delay CKD Progression

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Study demonstrates decreased risk of end-stage renal disease and all-cause mortality.

Anemia Burden in Chronic Kidney Disease Described

Anemia Burden in Chronic Kidney Disease Described

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The prevalence of low hemoglobin levels increases with declining renal function.

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced glomerular filtration rate ranked similarly to high total cholesterol as a risk factor for disability-adjusted life years.

Tolvaptan Offers Sustained Slowing of Renal Function Decline in ADPKD

Tolvaptan Offers Sustained Slowing of Renal Function Decline in ADPKD

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Open-label extension study confirms disease-modifying effect on eGFR, but not total kidney volume growth.

AKI Predictors in PE Patients Identified

AKI Predictors in PE Patients Identified

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Chronic kidney disease and anemia are associated with an increased risk for acute kidney injury in patients with pulmonary embolism.

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