Chronic Kidney Disease

Rapid Loss of Kidney Function Linked to Obesity

Rapid Loss of Kidney Function Linked to Obesity

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Large study shows the association is more pronounced with increasing age.

Nonalbuminuric CKD May Increase Mortality in Type 1 Diabetes

Nonalbuminuric CKD May Increase Mortality in Type 1 Diabetes

Nonalbuminuric chronic kidney disease was linked to increases in all-cause and cardiovascular mortality, but not albuminuria or end-stage renal disease.

High Phosphorus Levels Predict CKD Progression, Early Death

High Phosphorus Levels Predict CKD Progression, Early Death

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Every 1 mg/dL increase in serum phosphorus level was linked with 36% greater odds of kidney failure among non-dialysis CKD patients.

Hyperphosphatemia Increases Mortality in Critically Ill Patients

Hyperphosphatemia Increases Mortality in Critically Ill Patients

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High phosphate levels are associated with 3.3-fold increased odds of 28-day in-hospital mortality.

Preventing Diabetic Kidney Disease

Preventing Diabetic Kidney Disease

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A multidisciplinary team-based approach to diabetes management may help prevent complications like diabetic kidney disease.

Late Life CKD Possibly Linked to Higher Midlife Blood Pressure

Late Life CKD Possibly Linked to Higher Midlife Blood Pressure

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New findings may offer possible strategies for preventing renal function decline.

Hyponatremia Increases Death Risk in Heart Failure Patients

Hyponatremia Increases Death Risk in Heart Failure Patients

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Study of Asian patients found that the 12-month mortality rate was signi­ficantly higher in those with than without hyponatremia at hospital admission for heart failure.

Topical Vitamin D May Relieve CKD-Related Pruritus

Topical Vitamin D May Relieve CKD-Related Pruritus

Significant improvement in skin dryness with topical vitamin D without major side effects.

Kidney Function Decline in Men Linked to Lower Alcohol Intake

Kidney Function Decline in Men Linked to Lower Alcohol Intake

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Frequent exercise also increases the odds of kidney function loss.

TMAO Implicated As a Cardiovascular Risk Factor in CKD

TMAO Implicated As a Cardiovascular Risk Factor in CKD

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As renal function declines, levels of trimethylamine-N-oxide increase, and this correlates with increased atherosclerosis burden.

Tyrosine Kinase Inhibitors Appear Safe in CML Patients With CKD

Tyrosine Kinase Inhibitors Appear Safe in CML Patients With CKD

In these patients, no further decline in GFR, regardless of TKI used.

Blacks at Higher Risk of Sudden Cardiac Arrest

Blacks at Higher Risk of Sudden Cardiac Arrest

Higher rates of sudden cardiac arrest are seen in blacks versus whites and often at younger ages.

Study Probes Boiling Methods for Cutting Phosphorus in Meat

Study Probes Boiling Methods for Cutting Phosphorus in Meat

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Boiling sliced meat in a pressure cooker filled with soft water may be a promising way for dialysis patients to reduce phosphorus intake.

Food Additives Found to Raise Serum Phosphorus

Food Additives Found to Raise Serum Phosphorus

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Study implicates dairy products, cereals, and grains containing inorganic phosphate additives.

Medications Contribute to Phosphate Intake

Medications Contribute to Phosphate Intake

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Among the phosphate-containing medicinal products prescribed to chronic kidney disease patients, 76% may contain absorbable phosphate.

Study: 30% Decline in eGFR Over 2 Years Strongly Predicts ESRD

Study: 30% Decline in eGFR Over 2 Years Strongly Predicts ESRD

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Baseline eGFR, higher phosphorus, proteinuria, and male gender, also are associated with an elevated risk of end-stage renal disease in patients with chronic kidney disease.

Gout Increases Risk of Erectile Dysfunction

Gout Increases Risk of Erectile Dysfunction

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Gout is associated with an elevated likelihood of both organic and psychogenic ED.

Drug Controls Hyperkalemia in Diabetic Kidney Disease

Drug Controls Hyperkalemia in Diabetic Kidney Disease

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Patiromer's efficacy and safety confirmed out to 52 weeks.

ECG Metrics May Predict Cardiac Deaths in CKD Patients

ECG Metrics May Predict Cardiac Deaths in CKD Patients

ECG Metrics are stronger as markers for cardiovascular death than for all-cause mortality or noncardiovascular death.

Kidney Failure Risk, Ammonia Excretion Linked

Kidney Failure Risk, Ammonia Excretion Linked

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Study implicates an inability of a CKD patient's kidneys to excrete the daily acid load.

Poorly Controlled Diabetes May Increase Dementia

Poorly Controlled Diabetes May Increase Dementia

Older patients with more diabetes complications have greater cognitive decline, study finds.

Chronic Kidney Disease Raises Fracture Risk in Children

Chronic Kidney Disease Raises Fracture Risk in Children

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Fracture rates are 2.4- to 3-fold higher than rates found in the general population of children and adolescents.

Chronic Kidney Disease Risk Higher in Female Diabetics

Chronic Kidney Disease Risk Higher in Female Diabetics

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In a study, CKD was 35% more likely to develop in female than male diabetics in adjusted analyses that took into account death as a competing risk.

Risk Factors for CKD Progression ID'd

Risk Factors for CKD Progression ID'd

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Proteinuria, hyperphosphatemia, anemia linked more rapid annual decline in eGFR.

CKD Model May Improve Care via Electronic Health Records

CKD Model May Improve Care via Electronic Health Records

CKD, which is mainly defined by laboratory abnormalities, is a suitable EHR phenotype.

Metformin Use in Advanced CKD Raises Death Risk

Metformin Use in Advanced CKD Raises Death Risk

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Study reveals a 35% increase in all-cause mortality risk compared with non-use.

Cholecalciferol May Be Superior for Treating Vitamin D Deficiency

Cholecalciferol May Be Superior for Treating Vitamin D Deficiency

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Treatment with this compound resulted in higher circulating levels of 25(OH)D compared with ergocalciferol in Hispanic CKD patients.

Dysfunctional HDL May Contribute to Excess CVD Risk in CKD Patients

Dysfunctional HDL May Contribute to Excess CVD Risk in CKD Patients

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After standard lipid treatments, CKD patients still have up to a 70% residual risk of cardiovascular disease.

Vitamin D May Slow CKD Progression in Children

Vitamin D May Slow CKD Progression in Children

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In a study, renal survival increased by 8.2% with each 10 nmol/L increment in baseline levels of 25-hydroxyvitamin D.

Many Beverages Contain Hidden Phosphorus

Many Beverages Contain Hidden Phosphorus

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A study found that 78% of popular drinks, from flavored waters to lemonades to iced teas, contain far more phosphorus than listed in nutritional databases.

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