Chronic Kidney Disease

Higher Systolic BP Target Recommended for Older Patients

Higher Systolic BP Target Recommended for Older Patients

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New guidelines suggest aiming for a systolic pressure less than 150 mm Hg in hypertensive individuals aged 60 or older.

Metformin Linked With Lower Mortality, Better Outcomes in CKD

Metformin Linked With Lower Mortality, Better Outcomes in CKD

Metformin is associated with reduced all-cause mortality in patients with CKD, CHF, or CLD with hepatic impairment.

CKD Patients May Live Longer on a Plant-Based Diet

CKD Patients May Live Longer on a Plant-Based Diet

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Kidney disease patients who regularly consumed produce, legumes, cereals, whole grains, and fiber had a 27% lower risk of death compared with those who did not.

Pre-dialysis CKD Is a Risk Factor for Serious Infection

Pre-dialysis CKD Is a Risk Factor for Serious Infection

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Lower eGFR and higher ACR are associated with an elevated risk of infection-related hospitalization and infection-related death.

Novel Biomarker Can Predict Kidney Damage in Type 2 Diabetes

Novel Biomarker Can Predict Kidney Damage in Type 2 Diabetes

Urine haptoglobin, is a novel biomarker and complement to urine albumin for predicting kidney damage in patients with type 2 diabetes.

Using a Multidisciplinary Team Cost-Effective in CKD

Using a Multidisciplinary Team Cost-Effective in CKD

Multidisciplinary care program alleviates the much larger cost of dialysis.

Sodium Reduction May Improve Albuminuria in Nondiabetic CKD

Sodium Reduction May Improve Albuminuria in Nondiabetic CKD

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Reducing sodium consumption to about 2,500 mg daily was associated with albuminuria improvement.

Smoking Decreases Effectiveness of CKD Medications

Smoking Decreases Effectiveness of CKD Medications

The researchers found that kidney function worsened faster in smokers compared to nonsmokers and those who quit.

Constipation Associated With CKD, ESRD Risk

Constipation Associated With CKD, ESRD Risk

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Since constipation is common, the study findings may be important for public health.

Decreased Renal Function, Higher Vitamin D Levels Linked

Decreased Renal Function, Higher Vitamin D Levels Linked

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The association is independent of albumin-to-creatinine ratio, according to investigators.

Smoking Ups Morbidity, Mortality in CKD, But Not ESRD Risk

Smoking Ups Morbidity, Mortality in CKD, But Not ESRD Risk

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Current smoking was linked with higher risks for lung cancer and upper aerodigestive cancer by 9 and 5 times, respectively.

Elevated CRP Linked With CKD Risk in Rheumatoid Arthritis

Elevated CRP Linked With CKD Risk in Rheumatoid Arthritis

Tight control of inflammation in RA may provide additional benefits for preventing the development of CKD.

Semaglutide Does Not Appear to Increase CV Risks

Semaglutide Does Not Appear to Increase CV Risks

Study confirms the noninferiority of semaglutide.

Proton Pump Inhibitors May Up CKD Risk

Proton Pump Inhibitors May Up CKD Risk

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PPI use was associated with 10% increased odds of CKD and 76% increased odds of death.

A-Fib Can Lead to CKD, CVD, More

A-Fib Can Lead to CKD, CVD, More

Review links atrial fibrillation to increased risk for cardiovascular events, kidney disease, not just stroke.

Even Mild CKD Raises Gastrointestinal Bleeding Risk

Even Mild CKD Raises Gastrointestinal Bleeding Risk

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Higher albuminuria emerges as a significant predictor of hospitalization for GI bleeding.

CKD Progression Delay Observed With Folic Acid Therapy

CKD Progression Delay Observed With Folic Acid Therapy

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Enalapril plus folic acid treatment was associated with a 56% reduction in the odds of CKD progression compared with enalapril alone.

DASH Diet May Protect Against Kidney Disease

DASH Diet May Protect Against Kidney Disease

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In a study, CKD was 16% less likely to develop in low adherers to a DASH dietary pattern.

Albuminuria Linked to Higher Blood Pressure at Night

Albuminuria Linked to Higher Blood Pressure at Night

Significantly higher nighttime systolic blood pressure, especially in patients with diabetes and low eGFR.

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

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A hemoglobin level of 10.5 g/dL offers the optimal balance of cost and quality adjusted life years, researchers conclude.

Diabetes May Increase Anemia Risk in CKD Patients

Diabetes May Increase Anemia Risk in CKD Patients

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The odds of developing anemia were 2-fold greater among patients with than without diabetes mellitus.

Hyperkalemia Drug Lowers Aldosterone

Hyperkalemia Drug Lowers Aldosterone

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Study demonstrates a novel effect of patiromer treatment in hyperkalemic CKD patients

Anemic CKD Patients Have Lower Health-Related Quality of Life

Anemic CKD Patients Have Lower Health-Related Quality of Life

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Anemia was associated with impaired activity levels at CKD stages 3, 4, and dialysis.

Poor CVD Drug Adherence Before Dialysis Predicts Worse Survival

Poor CVD Drug Adherence Before Dialysis Predicts Worse Survival

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Patients who took CVD medications less than 60% of the time before starting dialysis had a 21% increased risk of early death after dialysis initiation.

Serum Creatinine Doubling Ups Cardiovascular Risks in Diabetes Patients

Serum Creatinine Doubling Ups Cardiovascular Risks in Diabetes Patients

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Doubling of serum creatinine occured in 1,262 patients studied.

Intermediate HDL Cholesterol Levels Linked With Better Survival

Intermediate HDL Cholesterol Levels Linked With Better Survival

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Researchers found a U-shaped relationship between HDL cholesterol and premature death across all levels of kidney function.

Intensive BP Control in CKD Improves Survival

Intensive BP Control in CKD Improves Survival

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Black CKD patients with strict blood pressure control had a 19% lower risk of premature death.

Hepatitis C in CKD: Challenges and Opportunities

Hepatitis C in CKD: Challenges and Opportunities

The availability of direct-acting antiviral drugs may enable eradication of hepatitis C virus and improve outcomes.

No Rise in CKD Stage 3 and 4 in the US

No Rise in CKD Stage 3 and 4 in the US

Since early 2000s, little increase in prevalence of stage 3 and 4 chronic kidney disease.

Predialysis Nephrology Care Predicts Health Outcomes

Predialysis Nephrology Care Predicts Health Outcomes

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Patients who made more frequent predialysis visits to a nephrologist had a lower risk of severe anemia at dialysis initiation.

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