Chronic Kidney Disease

Sodium Reduction May Improve Albuminuria in Nondiabetic CKD

Sodium Reduction May Improve Albuminuria in Nondiabetic CKD

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Reducing sodium consumption to about 2,500 mg daily was associated with albuminuria improvement.

Smoking Decreases Effectiveness of CKD Medications

Smoking Decreases Effectiveness of CKD Medications

The researchers found that kidney function worsened faster in smokers compared to nonsmokers and those who quit.

Constipation Associated With CKD, ESRD Risk

Constipation Associated With CKD, ESRD Risk

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Since constipation is common, the study findings may be important for public health.

Decreased Renal Function, Higher Vitamin D Levels Linked

Decreased Renal Function, Higher Vitamin D Levels Linked

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The association is independent of albumin-to-creatinine ratio, according to investigators.

Smoking Ups Morbidity, Mortality in CKD, But Not ESRD Risk

Smoking Ups Morbidity, Mortality in CKD, But Not ESRD Risk

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Current smoking was linked with higher risks for lung cancer and upper aerodigestive cancer by 9 and 5 times, respectively.

Elevated CRP Linked With CKD Risk in Rheumatoid Arthritis

Elevated CRP Linked With CKD Risk in Rheumatoid Arthritis

Tight control of inflammation in RA may provide additional benefits for preventing the development of CKD.

Semaglutide Does Not Appear to Increase CV Risks

Semaglutide Does Not Appear to Increase CV Risks

Study confirms the noninferiority of semaglutide.

Proton Pump Inhibitors May Up CKD Risk

Proton Pump Inhibitors May Up CKD Risk

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PPI use was associated with 10% increased odds of CKD and 76% increased odds of death.

A-Fib Can Lead to CKD, CVD, More

A-Fib Can Lead to CKD, CVD, More

Review links atrial fibrillation to increased risk for cardiovascular events, kidney disease, not just stroke.

Even Mild CKD Raises Gastrointestinal Bleeding Risk

Even Mild CKD Raises Gastrointestinal Bleeding Risk

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Higher albuminuria emerges as a significant predictor of hospitalization for GI bleeding.

CKD Progression Delay Observed With Folic Acid Therapy

CKD Progression Delay Observed With Folic Acid Therapy

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Enalapril plus folic acid treatment was associated with a 56% reduction in the odds of CKD progression compared with enalapril alone.

DASH Diet May Protect Against Kidney Disease

DASH Diet May Protect Against Kidney Disease

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In a study, CKD was 16% less likely to develop in low adherers to a DASH dietary pattern.

Albuminuria Linked to Higher Blood Pressure at Night

Albuminuria Linked to Higher Blood Pressure at Night

Significantly higher nighttime systolic blood pressure, especially in patients with diabetes and low eGFR.

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

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A hemoglobin level of 10.5 g/dL offers the optimal balance of cost and quality adjusted life years, researchers conclude.

Diabetes May Increase Anemia Risk in CKD Patients

Diabetes May Increase Anemia Risk in CKD Patients

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The odds of developing anemia were 2-fold greater among patients with than without diabetes mellitus.

Hyperkalemia Drug Lowers Aldosterone

Hyperkalemia Drug Lowers Aldosterone

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Study demonstrates a novel effect of patiromer treatment in hyperkalemic CKD patients

Anemic CKD Patients Have Lower Health-Related Quality of Life

Anemic CKD Patients Have Lower Health-Related Quality of Life

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Anemia was associated with impaired activity levels at CKD stages 3, 4, and dialysis.

Poor CVD Drug Adherence Before Dialysis Predicts Worse Survival

Poor CVD Drug Adherence Before Dialysis Predicts Worse Survival

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Patients who took CVD medications less than 60% of the time before starting dialysis had a 21% increased risk of early death after dialysis initiation.

Serum Creatinine Doubling Ups Cardiovascular Risks in Diabetes Patients

Serum Creatinine Doubling Ups Cardiovascular Risks in Diabetes Patients

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Doubling of serum creatinine occured in 1,262 patients studied.

Intermediate HDL Cholesterol Levels Linked With Better Survival

Intermediate HDL Cholesterol Levels Linked With Better Survival

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Researchers found a U-shaped relationship between HDL cholesterol and premature death across all levels of kidney function.

Intensive BP Control in CKD Improves Survival

Intensive BP Control in CKD Improves Survival

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Black CKD patients with strict blood pressure control had a 19% lower risk of premature death.

Hepatitis C in CKD: Challenges and Opportunities

Hepatitis C in CKD: Challenges and Opportunities

The availability of direct-acting antiviral drugs may enable eradication of hepatitis C virus and improve outcomes.

No Rise in CKD Stage 3 and 4 in the US

No Rise in CKD Stage 3 and 4 in the US

Since early 2000s, little increase in prevalence of stage 3 and 4 chronic kidney disease.

Predialysis Nephrology Care Predicts Health Outcomes

Predialysis Nephrology Care Predicts Health Outcomes

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Patients who made more frequent predialysis visits to a nephrologist had a lower risk of severe anemia at dialysis initiation.

Higher Saxagliptin Dose OK for Diabetes Patients With Moderate CKD

Higher Saxagliptin Dose OK for Diabetes Patients With Moderate CKD

A post-hoc analysis was conducted on the effect of saxagliptin 2.5 mg and 5 mg vs. placebo on glycemic measures.

Natural Vitamin D Supplement Effective for Nondialysis CKD-MBD

Natural Vitamin D Supplement Effective for Nondialysis CKD-MBD

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Over 33 months, the 25-hydroxyvitamin D level of ergocalciferol recipients increased significantly from 15.14 to 37.32 ng/mL.

Sulfonylureas May Increase Hypoglycemia in Late-Stage CKD Patients

Sulfonylureas May Increase Hypoglycemia in Late-Stage CKD Patients

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Notably, gliclazide did not appear superior to other sulfonylureas.

Restricting Fat May Cut Chronic Kidney Disease Risk

Restricting Fat May Cut Chronic Kidney Disease Risk

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Study implicates higher consumption of advanced glycation end products through dietary fat.

Many Older Adults With CKD Functionally Impaired

Many Older Adults With CKD Functionally Impaired

Nearly 28% of study participants demonstrated difficulty with 1 or more activities of daily living, a history of falls, and cognitive impairment.

Depressed Diabetes Patients More Likely to Develop CKD

Depressed Diabetes Patients More Likely to Develop CKD

Patients with depression were younger, had higher eGFR, and more comorbidities.

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