Chronic Kidney Disease

CKD Progression Delay Observed With Folic Acid Therapy

CKD Progression Delay Observed With Folic Acid Therapy

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Enalapril plus folic acid treatment was associated with a 56% reduction in the odds of CKD progression compared with enalapril alone.

DASH Diet May Protect Against Kidney Disease

DASH Diet May Protect Against Kidney Disease

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In a study, CKD was 16% less likely to develop in low adherers to a DASH dietary pattern.

Albuminuria Linked to Higher Blood Pressure at Night

Albuminuria Linked to Higher Blood Pressure at Night

Significantly higher nighttime systolic blood pressure, especially in patients with diabetes and low eGFR.

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

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A hemoglobin level of 10.5 g/dL offers the optimal balance of cost and quality adjusted life years, researchers conclude.

Diabetes May Increase Anemia Risk in CKD Patients

Diabetes May Increase Anemia Risk in CKD Patients

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The odds of developing anemia were 2-fold greater among patients with than without diabetes mellitus.

Hyperkalemia Drug Lowers Aldosterone

Hyperkalemia Drug Lowers Aldosterone

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Study demonstrates a novel effect of patiromer treatment in hyperkalemic CKD patients

Anemic CKD Patients Have Lower Health-Related Quality of Life

Anemic CKD Patients Have Lower Health-Related Quality of Life

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Anemia was associated with impaired activity levels at CKD stages 3, 4, and dialysis.

Poor CVD Drug Adherence Before Dialysis Predicts Worse Survival

Poor CVD Drug Adherence Before Dialysis Predicts Worse Survival

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Patients who took CVD medications less than 60% of the time before starting dialysis had a 21% increased risk of early death after dialysis initiation.

Serum Creatinine Doubling Ups Cardiovascular Risks in Diabetes Patients

Serum Creatinine Doubling Ups Cardiovascular Risks in Diabetes Patients

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Doubling of serum creatinine occured in 1,262 patients studied.

Intermediate HDL Cholesterol Levels Linked With Better Survival

Intermediate HDL Cholesterol Levels Linked With Better Survival

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Researchers found a U-shaped relationship between HDL cholesterol and premature death across all levels of kidney function.

Intensive BP Control in CKD Improves Survival

Intensive BP Control in CKD Improves Survival

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Black CKD patients with strict blood pressure control had a 19% lower risk of premature death.

Hepatitis C in CKD: Challenges and Opportunities

Hepatitis C in CKD: Challenges and Opportunities

The availability of direct-acting antiviral drugs may enable eradication of hepatitis C virus and improve outcomes.

No Rise in CKD Stage 3 and 4 in the US

No Rise in CKD Stage 3 and 4 in the US

Since early 2000s, little increase in prevalence of stage 3 and 4 chronic kidney disease.

Predialysis Nephrology Care Predicts Health Outcomes

Predialysis Nephrology Care Predicts Health Outcomes

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Patients who made more frequent predialysis visits to a nephrologist had a lower risk of severe anemia at dialysis initiation.

Higher Saxagliptin Dose OK for Diabetes Patients With Moderate CKD

Higher Saxagliptin Dose OK for Diabetes Patients With Moderate CKD

A post-hoc analysis was conducted on the effect of saxagliptin 2.5 mg and 5 mg vs. placebo on glycemic measures.

Natural Vitamin D Supplement Effective for Nondialysis CKD-MBD

Natural Vitamin D Supplement Effective for Nondialysis CKD-MBD

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Over 33 months, the 25-hydroxyvitamin D level of ergocalciferol recipients increased significantly from 15.14 to 37.32 ng/mL.

Sulfonylureas May Increase Hypoglycemia in Late-Stage CKD Patients

Sulfonylureas May Increase Hypoglycemia in Late-Stage CKD Patients

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Notably, gliclazide did not appear superior to other sulfonylureas.

Restricting Fat May Cut Chronic Kidney Disease Risk

Restricting Fat May Cut Chronic Kidney Disease Risk

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Study implicates higher consumption of advanced glycation end products through dietary fat.

Many Older Adults With CKD Functionally Impaired

Many Older Adults With CKD Functionally Impaired

Nearly 28% of study participants demonstrated difficulty with 1 or more activities of daily living, a history of falls, and cognitive impairment.

Depressed Diabetes Patients More Likely to Develop CKD

Depressed Diabetes Patients More Likely to Develop CKD

Patients with depression were younger, had higher eGFR, and more comorbidities.

Higher Red Meat Intake Raises Kidney Failure Risk

Higher Red Meat Intake Raises Kidney Failure Risk

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Highest vs lowest quartile of intake is associated with a 40% increased risk.

Hip Fracture Rate Higher in Non-Dialysis CKD

Hip Fracture Rate Higher in Non-Dialysis CKD

Patients with non-dialysis chronic kidney disease (CKD) may be at elevated risk for hip fracture, according the Journal of Bone and Mineral Research.

Blacks With Diabetes and CKD Have Higher CVD Risk

Blacks With Diabetes and CKD Have Higher CVD Risk

Odds of cardiovascular mortality 14.8% higher in black Americans with both conditions.

Novel Hyperkalemia Drugs May Help Optimize Use of RAAS Inhibitors

Novel Hyperkalemia Drugs May Help Optimize Use of RAAS Inhibitors

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High potassium levels associated with the use of renin-angiotensin-aldosterone system inhibitors limit their use in CKD patients.

Slower Kidney Disease Progression Observed With Empagliflozin Use

Slower Kidney Disease Progression Observed With Empagliflozin Use

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Incident or worsening nephropathy was observed in 12.7% of patients receiving empagliflozin compared with 18.8% of those receiving placebo.

Chronic Kidney Disease Impairs Digestive Function

Chronic Kidney Disease Impairs Digestive Function

CKD associated with dysmotility and reduces fasting and post-prandial small bowel water.

Low Midlife Fitness May Predict Future CKD

Low Midlife Fitness May Predict Future CKD

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High vs. low fitness levels in midlife lowered CKD risk in later life by 34%.

Kidney Stone Procedures Found Not to Raise CKD Risk

Kidney Stone Procedures Found Not to Raise CKD Risk

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Researchers find an increased risk for elevated serum creatinine, but not chronic kidney disease or all-cause mortality.

Low HRQoL May Increase CV Event Risk in CKD Patients

Low HRQoL May Increase CV Event Risk in CKD Patients

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The researchers found no relationship between poor quality of life and CKD progression.

Increased Rate of Hip Fracture in Non-Dialysis CKD

Increased Rate of Hip Fracture in Non-Dialysis CKD

Increased age-standardized rates of hip fracture, post-hip fracture mortality, higher resource use.

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