Chronic Kidney Disease

Advanced CKD Linked to Worse Post-CABG Outcomes

Advanced CKD Linked to Worse Post-CABG Outcomes

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Study reveals significantly elevated risk of in-hospital mortality, postoperative infection, and acute kidney injury.

Older Age Predicts Renal Function Decline in Living Donors

Older Age Predicts Renal Function Decline in Living Donors

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Mean estimated glomerular filtration rate decreases by 0.57 mL/min/1.73 m2 annually with each 1-year increase in age at donation.

CKD Raises Risk of Poor Urologic Surgery Outcomes

CKD Raises Risk of Poor Urologic Surgery Outcomes

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Major perioperative complications and death are more likely in patients with chronic kidney disease stages 3-5.

Alcohol May Protect Kidney Function in Men

Alcohol May Protect Kidney Function in Men

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Heavy and binge drinking found to significantly decrease the likelihood of renal dysfunction.

CABG Outcomes Better in Kidney Disease Patients

CABG Outcomes Better in Kidney Disease Patients

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It is associated with better long-term survival and reduced risk of revascularization and myocardial infarction compared with PCI.

Pre-Surgery Anemia Ups CKD Patients' Risks

Pre-Surgery Anemia Ups CKD Patients' Risks

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Low hemoglobin levels increase the risk of death, sepsis, and cerebrovascular accidents following cardiac surgery.

Chronic Kidney Disease Linked to Kidney Stones

Chronic Kidney Disease Linked to Kidney Stones

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A history of nephrolithiasis was associated with a nearly 2-fold increased odds of chronic kidney disease in women.

CKD Risk Factors Present Decades Prior to Diagnosis

CKD Risk Factors Present Decades Prior to Diagnosis

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In a study, hypertension, obesity, and higher triglycerides predicted development of chronic kidney disease 30 years later.

Low Bicarbonate Predicts Rapid Renal Function Decline

Low Bicarbonate Predicts Rapid Renal Function Decline

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Serum bicarbonate could potentially be used to identify patients at elevated risk for chronic kidney disease.

HCV Infection Raises Kidney Failure Risk

HCV Infection Raises Kidney Failure Risk

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Hepatitis C virus infection increases CKD patients' likelihood of progressing to end-stage renal disease by 32%.

Low Sodium Diet May Not Reduce Renal Risks

Low Sodium Diet May Not Reduce Renal Risks

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Researchers find no association between sodium excretion and decline in eGFR.

High Uric Acid May Hasten Dialysis Initiation

High Uric Acid May Hasten Dialysis Initiation

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Renal function decline is not accelerated, however.

 Homocysteine Levels Elevated in Gout Patients

Homocysteine Levels Elevated in Gout Patients

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Korean study also revealed an inverse association between serum homocysteine levels and renal function.

Cardiovascular Events Hike CKD Patients' ESRD Risk

Cardiovascular Events Hike CKD Patients' ESRD Risk

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Heart failure, myocardial infarction, or stroke also increase the risk of death prior to ESRD.

CKD Stage 4 Patients Have Equal Risk of ESRD, Death

CKD Stage 4 Patients Have Equal Risk of ESRD, Death

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If renal replacement therapy planning were started only when patients reached CKD stage 5, many patients would not be adequately prepared, researchers said.

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

The Need for a Kidney Research Prize: Interview with Sharon Moe, MD

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Dr. Moe spoke about the importance of nephrology research and how a prize competition can facilitate the process.

Advanced CKD Increases C. Difficile Infection Risk

Advanced CKD Increases C. Difficile Infection Risk

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A nearly 5-fold higher risk of Clostridium difficile infection observed in patients with end-stage renal disease requiring dialysis.

Parental CVD Adversely Impacts Offsprings' Kidneys

Parental CVD Adversely Impacts Offsprings' Kidneys

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Study reveals a more rapid decline in annual eGFR among individuals whose parents had cardiovascular disease.

"Doc, Did You Check My Cholesterol?"

"Doc, Did You Check My Cholesterol?"

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Many patients still insist that I need to check and manage their cholesterol.

Walking Tied to Better CKD Outcomes

Walking Tied to Better CKD Outcomes

Lower risk of overall mortality, renal replacement therapy seen with more walking.

Lower Cholesterol Has No Effect on Kidney Disease Progression

Lower Cholesterol Has No Effect on Kidney Disease Progression

Cholesterol-lowering therapy is indicated in CKD patients to prevent cardiovascular risk.

Carotid Plaque May Predict Coronary Artery Stenosis

Carotid Plaque May Predict Coronary Artery Stenosis

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Increased maximal carotid artery plaque is associated with a greater likelihood of occlusive coronary disease in patients with and without CKD.

Kidney Function Assessment: The Need for a Confirmatory Test

Confirmation of creatinine-based eGFR should be performed in select circumstances using, where appropriate, either measured GFR or cystatin C.

ACTH May Be Useful for Membranous Nephropathy

ACTH May Be Useful for Membranous Nephropathy

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In a 5-year follow-up study, 27 of 28 patients treated with adrenocorticotropic hormone had complete or partial remission.

CKD Hikes Risk of Cancer, Cancer-Related Death

CKD Hikes Risk of Cancer, Cancer-Related Death

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An eGFR below 45 mL/min/1.73 m2 was associated with a 55% increased risk of death from cancer versus an eGFR of 90 or higher.

Phosphorus Control Using PTH Tested

Phosphorus Control Using PTH Tested

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In mice with and without CKD, phosphorus levels decreased by an average of 35% by 6 hours after injection with long-acting PTH.

Value of ESAs in Avoiding Transfusion Questionable

Value of ESAs in Avoiding Transfusion Questionable

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In 3 trials, the annual cost for preventing 1 patient from being transfused varied from $61,188 to $317,988.

High Phosphorus Ups Anemia Risk in the Non-CKD Population

High Phosphorus Ups Anemia Risk in the Non-CKD Population

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Each 0.5 mg/dL increment in phosphorus was associated with a 7% increased risk of anemia.

Inappropriate ESA Use Reduced by Pharmacy Protocol

Inappropriate ESA Use Reduced by Pharmacy Protocol

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Ordering process cut the number of epoetin alfa doses by 71% and medication costs by 69%.

Safety Profiles of IV Iron Products Compared

Safety Profiles of IV Iron Products Compared

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In a head-to-head comparison, researchers observed a higher rate of adverse events with iron dextran than iron sucrose or ferric gluconate.

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