Niacinamide Helps Lower Phosphorus

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In an eight-week study of 15 patients, oral niacinamide added to standard phosphorus-lowering therapies resulted in a modest yet significant reduction in plasma phosphorus levels in patients on peritoneal dialysis, investigators reported in Peritoneal Dialysis International (2009;29:562-567).

Patients were randomized to receive niacinamide or placebo in addition to standard phosphate binders. Plasma phosphorus decreased by an average 0.7 mg/dL in the niacinamide group but increased by an average 0.4 mg/dL in the placebo arm.

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