CKD Is a Risk Factor for UTUC

Researchers found elevated incidences of upper tract urothelial carcinoma (UTUC) in patients with CKD.
Researchers found elevated incidences of upper tract urothelial carcinoma (UTUC) in patients with CKD.

Chronic kidney disease (CKD) is a risk factor for upper tract urothelial carcinoma (UTUC), a study found.

Using Taiwan's Longitudinal Health Insurance Database, Jeng-Sheng Chen, MD, of Sinying Hospital in Sinying, and colleagues compared 45,321 CKD patients and 181,284 age- and gender-matched controls. The CKD group had a significantly higher incidence UTUC than the controls (0.22% vs. 0.07%). In multivariate analysis, CKD was associated with a 63% increased risk UTUC, investigators reported in Medicine (Baltimore) (2016;95:e3255). The risk increased to 72% after excluding patients who progressed to dialysis and kidney transplantation. Results also showed that female gender was associated with a 38% increased UTUC risk.

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