Anthropometric Body Fat Measurements Can Estimate Renal Function Decline

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The researchers found that 17% of the population experienced KF decline, while incident CKD occurred in 17% of those at risk.
The researchers found that 17% of the population experienced KF decline, while incident CKD occurred in 17% of those at risk.

(HealthDay News) — Anthropometric measures of body fat can predict kidney function (KF) decline in older adults, according to a study published online in the Clinical Journal of the American Society of Nephrology.

Magdalena Madero, MD, from the National Heart Institute in Mexico City, and colleagues compared the correlation of computed tomography (CT) and anthropometric measures of obesity with kidney outcomes in the Health Aging and Body Composition Study. They examined the correlation with decline in KF and incident kidney disease using data for 2489 individuals (mean age, 74 ± 3 years).

The researchers found that 17% of the population experienced KF decline, while incident chronic kidney disease (CKD) occurred in 17% of those at risk. There were significant correlations for subcutaneous adipose tissue, visceral abdominal fat (VAT), intermuscular fat area, body mass index (BMI), and waist circumference (WC) with KF decline in continuous models. With regard to KF decline, there was a significant interaction between VAT and CKD (P =.008). There were correlations for VAT, BMI, and WC with incident CKD. On inclusion of other exposure variables in the same model, only VAT remained a significant risk factor for incident CKD.

"Anthropometric measures of body fat appear to provide as consistent estimates of KF decline risk as CT measures in elders," the authors write.

Reference

  1. Madero M, Katz R, Murphy R, et al. Comparison between Different Measures of Body Fat with Kidney Function Decline and Incident CKD. Clin J Am Soc Nephrol. 18 May 2017. doi: 10.2215/CJN.07010716
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