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No Increased Fracture Rate with Decreasing eGFR

May 16, 2012

ST. JOHN'S, NEWFOUNDLAND—A new analysis suggests there is no association between lower estimated glomerular filtration rate (eGFR) and non-traumatic hip-, vertebral- or wrist-fracture rates. This contradicts earlier studies showing a four-fold higher fracture rate with end-stage renal disease (ESRD).
 

Novel Formulation Corrects Vitamin D, Lowers iPTH

May 13, 2012

NATIONAL HARBOR, Md.—An investigational treatment safely and effectively lowers elevated plasma intact parathyroid hormone (iPTH) levels in patients with stage 3 or 4 chronic kidney disease and vitamin D deficiency, researchers reported at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

SHPT Linked to Vitamin D Deficiency in CKD Patients

May 12, 2012

NATIONAL HARBOR, Md.—Vitamin D deficiency is strongly associated with secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), according to data presented at the National Kidney Foundation (NKF) 2012 Spring Clinical Meetings.
 

Renal Ultrasound Use for CKD Patients Unchanged Despite Guidelines

May 12, 2012

NATIONAL HARBOR, Md.—Renal ultrasound use for patients with chronic kidney disease (CKD) has not changed significantly since the release of guidelines in 2002 recommending imaging studies for patients with CKD or who are at risk for it as a result of urinary stones, infections, and other factors.
 

CKD Elevates Risk of Post-Op AKI

May 12, 2012

NATIONAL HARBOR, Md.—Patients with chronic kidney disease (CKD) before undergoing surgical procedures are at increased risk of acute kidney injury (AKI) post-operatively, researchers reported at the National Kidney Foundation Spring Clinical Meetings.
 

CKD Patients May Need Higher 25D Levels

May 11, 2012

NATIONAL HARBOR, Md.—Levels of 25-hydroxyvitamin D (25D) higher than 20 ng/mL would be required to normalize intact parathyroid hormone (iPTH) in patients with stages 3 and 4 chronic kidney disease (CKD) with vitamin D insufficiency and secondary hyperparathyroidism, researchers concluded in a study presented at the National Kidney Foundation 2012 Spring Clinical Meetings.
 

Renal Function Can Improve Despite CKD, Study Finds

April 29, 2012

Data from 12 years of follow-up provides strong evidence that renal function can improve in some patients with hypertensive CKD.
 

PTH Rise in CKD Greater in Blacks

April 26, 2012

Changes in calcium, phosphorus, and 25-hydroxyvitamin-D explain only part of this racial difference
 

Fibrates May Impair Renal Function in Elderly Patients

April 19, 2012

Study reveals a twofold greater likelihood of being hospitalized for a rise in serum creatinine level
 

Normoalbuminuria Does Not Always Mean Normal Kidney Function

April 16, 2012

Many patients with diabetes have significant renal dysfunction despite having normo- or microalbuminuria, according to researchers.
 

With ESAs, Let Your Patient Be Your Guide: An Interview with Alan S. Kliger, MD

April 11, 2012

When using erythropoiesis-stimulating agents (ESAs) to correct anemia in patients with chronic kidney disease, focus less on hitting a given hemoglobin target and more on improving patient-perceived quality of life in such areas as fatigue, weakness, and shortness of breath, advises Alan S. Kliger, MD, Chief Medical Officer and Chief Quality Officer for the Saint Raphael Healthcare System in New Haven, Conn.
 

Endothelial Dysfunction in CKD Patients Linked to Calcitonin

April 05, 2012

Serum calcitonin is independently related with endothelial dysfunction in patients with chronic kidney disease (CKD), data suggest.
 

Oral Adsorbents, Probiotics an Inexpensive Way to Eliminate Uremic Toxics in CKD Patients

April 01, 2012

Patients on a traditional renal diet often find that they are consuming a relatively "unhealthy diet," meaning the diet is low in fresh fruits and vegetables, whole grain, and dairy products.
 

Physician Reminders Fail to Increase ACE/ARB Use

April 01, 2012

Treatment reminders fail to increase the rate at which primary care physicians (PCPs) prescribe ACE inhibitors or angiotensin receptor blockers (ARBs) for elderly patients with chronic kidney disease (CKD).
 

Part II: Clinical Challenges and Renal Considerations in Managing Gout

By James W. Lohr, MD April 01, 2012

A case study involving a 65-year-old man with chronic kidney disease and acute attacks of pain, swelling, and erythema in the first metatarsophalangeal joint.
 

Benefits of Automated eGFR Reporting Unclear

March 28, 2012

Having laboratories automatically provide an estimated glomerular filtration rate (eGFR) along with serum creatinine results does not appreciably increase the proportion of appropriate compared to inappropriate nephrology referrals, evidence suggests.
 

Obesity Does Not Affect CKD Progression Rate

March 22, 2012

Although obesity is known to increase a person's risk of developing chronic kidney disease (CKD), it has no effect on CKD progression, a study found.
 

Arteriovenous Fistulas May Increase Heart Failure Risk

March 21, 2012

Pre-emptive placement of an arteriovenous fistula (AVF) in pre-dialysis patients with advanced chronic kidney disease (CKD) may increase their risk of congestive heart failure (CHF), a study found.
 

Current and Future Approaches to Renal Protection through Blood Pressure Control

, , March 14, 2012

This is the title of a scheduled May 11 session (8:30-10:00 a.m.) at the National Kidney Foundation's 2012 Spring Clinical Meetings.
 

Less Strict BP Goal for CKD Patients May Be More Realistic

March 09, 2012

Researchers at the University of California, San Francisco, say treating chronic kidney disease (CKD) patients' blood pressure to 140/80 rather than the recommended level of 130/80 may be more realistic.
 

Lower Renal Function Boosts Risk of Infection-Related Hospitalizations

March 08, 2012

As renal function declines, the risk of infection-related hospitalizations increases, new findings suggest.
 

Bariatric Surgery Risks Rise as Renal Function Declines

March 06, 2012

Worsening renal function is associated with a greater risk of complications from bariatric surgery, researchers reported.
 

Clinical Challenges and Renal Considerations In Managing Gout

By William F. Finn, MD March 01, 2012

A case study examines the treatment of hyperuricemia and gout in a 57-year-old postmenopausal renal transplant recipient with intermittent gout attacks.
 

Vytorin Label Will Include Kidney Data

February 29, 2012

The FDA has approved new labeling for the cardiovascular agent Vytorin (ezetimibe/simvastatin) that will include data from the Study of Heart and Renal Protection (SHARP).
 

Highest Diabetes Death Rates Seen in Trials Selecting for CKD

February 24, 2012

Selection for chronic kidney disease associated with highest mortality rates in randomized trials
 

High, Low Potassium Raise Death Risk in Men with CKD

February 23, 2012

Hypo- and hyperkalemia are associated with higher mortality in male patients with chronic kidney disease (CKD) but not yet on dialysis, but this association varies by race, a study found.
 

Potential of FGF-23 Yet to Be Unleashed: An Interview with Orlando M. Gutiérrez, MD

February 15, 2012

Although it does not yet have a place in everyday practice, fibroblast growth factor 23 (FGF-23) may one day be an important marker of and therapeutic target for very early-stage chronic kidney disease for the clinical nephrologist. Orlando M. Gutiérrez, MD, Assistant Professor of Medicine in the Division of Nephrology at the University of Alabama at Birmingham, has studied in depth this bone-derived hormone, which regulates phosphorus and vitamin D.
 

Exercise Enhances Body Composition, Nutritional Status in Dialysis Patients

February 01, 2012

Research has shown that individuals who exercise have lower risk for chronic diseases than individuals who do not exercise.
 

CKD Incidence Higher in African Americans Than Whites

February 01, 2012

Researchers who analyzed 20-year follow-up data from a prospective study found that African Americans have a higher incidence of chronic kidney disease (CKD) than whites in part because of albuminuria.
 

Renal Function Decline Often Precedes Macroalbuminuria in Type 2 Diabetes

January 31, 2012

Decreases in glomerular filtration rate (GFR) frequently occur before the onset of macroalbuminuria in patients with type 2 diabetes, according to a study. A GFR decline that predicts development of end-stage renal disease (ESRD), however, strongly depends on progression to macroalbuminuria.
 

Kidney Cancer Tumor Size, Preoperative eGFR Linked

January 30, 2012

Tumor diameter and decreased preoperative estimated glomerular filtration rate (eGFR) are independently correlated in patients undergoing surgery for renal cell carcinoma (RCC), researchers concluded.
 

Myocardial Infarctions Frequently Unrecognized in Kidney Disease Patients

January 04, 2012

Myocardial infarction (MI) often goes unrecognized in patients with chronic kidney disease (CKD), and it is associated with a significantly increased risk of death, according to researchers.
 

Lab Tests Tip Off Employees to CKD, Other Conditions

December 16, 2011

Laboratory tests performed as part of employer-sponsored health risk assessments (HRA) revealed evidence that "newly identified" at least one of three common medical conditions in more than one third of adults, a study found.
 

FDA Committee Favors Peginesatide

December 15, 2011

The FDA's Oncologic Drugs Advisory Committee, in a 15 to 1 vote, has agreed that peginesatide demonstrates a favorable benefit/risk profile for use in treatment of dialysis patients with anemia resulting from chronic kidney disease (CKD).
 

Inflammatory Markers Predict Risk of Chronic Kidney Disease

December 09, 2011

Elevated levels of certain inflammatory markers are associated with an increased risk of developing chronic kidney disease (CKD), a study found.
 

High Fiber Intake Reduces Inflammation, Death Risk in CKD Patients

December 01, 2011

High intake of dietary fiber is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease (CKD), according to researchers.
 

Novel Therapy for CKD Anemia Advances

November 16, 2011

PHILADELPHIA—A novel treatment for chronic kidney disease (CKD) patients with anemia is showing positive results following a Phase 1/2 clinical trial, according to findings reported at Kidney Week 2011.
 

Higher Uric Acid Raises CKD Risk

November 01, 2011

Higher serum uric acid (SUA) levels increase the risk of chronic kidney disease (CKD), according to Korean researchers.
 

Drug-Eluting Stents Safe for Most Older CKD Patients

October 20, 2011

Drug-eluting stents are safe to use in older patients undergoing percutaneous coronary interventions regardless of renal function, researchers concluded.
 

Reduced Renal Function Raises Risk of Serious Infections

October 11, 2011

Decreased kidney function places elderly individuals at higher risk of infection- related hospitalization, according to a study.
 

AKI Patients Require Strong Assessment to Prevent Protein-Energy Wasting

October 11, 2011

Recent reports have demonstrated a link between acute kidney injury (AKI) and chronic kidney disease (CKD). Individuals with AKI are more likely to have CKD and eventually progress to end-stage renal disease.
 

Chronic Kidney Disease More Common in Lithotripsy Patients

October 05, 2011

Chronic kidney disease (CKD) is significantly more prevalent among patients who have undergone successful extracorporeal shockwave lithotripsy (ESWL) than among healthy individuals, a Japanese study found.
 

Renal Disease Risk Depends on Number of Metabolic Syndrome Components

September 15, 2011

Researchers at the Cleveland Clinic report that kidney disease risk increases along with the number of metabolic syndrome components. John Schieszer has the story in today's Medical Minute.
 

Omega-3 Fatty Acids May Decrease Inflammation and Mortality in CKD Patients

September 12, 2011

Lower ratios of omega-6 to omega-3 fatty acids are better for hemodialysis patients in terms of inflammation and survival, new data suggest.
 

Persistent Hematuria in Kids Portends ESRD

September 09, 2011

End-stage renal disease (ESRD) is more likely to develop in adolescents and young adults with persistent microscopic hematuria, according to a report in the Journal of the American Medical Association (2011;306:729-736).
 

Issues in Hypertension: An Interview with George Bakris, MD

September 01, 2011

George Bakris, MD, Professor of Medicine and Director of the Hypertensive Diseases Center at the University of Chicago Medical Center, is an internationally recognized hypertension expert who specializes in complicated or refractory cases. He spoke with Renal & Urology News about various aspects of treating hypertension in patients with chronic kidney disease.
 

Ambulatory BP Predicts Renal and CV Events

August 15, 2011

In a study of 436 patients with chronic kidney disease not on dialysis (mean age 65.1 years), ambulatory blood pressure (BP) measurements showed risk of both renal and cardiovascular (CV) events to be highest when daytime systolic BP was 135 mm Hg or higher, when diastolic BP was in the highest quintile, and when nighttime systolic BP was 124 mm Hg or higher.
 

Novel Drug Could Prevent Deaths in CKD Patients

August 08, 2011

Clinical trials show that bardoxolone methyl not only maintains renal function, but improves it.
 

Big Waists Raise CKD Patients' Death Risk

August 01, 2011

A large waist size increases the risk of death among patients with chronic kidney disease (CKD), data show.
 

FDA Agrees to Review NDA for Peginesatide

July 27, 2011

The FDA has agreed to review a New Drug Application (NDA) for peginesatide for the treatment of anemia associated with chronic kidney disease (CKD) in adult dialysis patients, according to a joint announcement by the two companies colloraborating on the development of the drug.
 

LDL Lowering Fails to Slow Renal Disease Progression

July 19, 2011

PRAGUE—Lowering LDL cholesterol (LDL) can prevent or even reverse atherosclerosis, but it does not do the same for the progression of chronic kidney disease (CKD).
 

Kidney Cancer vs. ESRD

, July 19, 2011

Incidentally detected renal tumors are increasingly diagnosed in patients with chronic kidney disease.
 

HDL from CDK Patients Loses Vasoprotective Effects

July 18, 2011

PRAGUE—HDL cholesterol (HDL) in patients with chronic kidney disease (CKD) loses its protective effect on vascular endothelium, new findings suggest. Rather than supporting the beneficial functions of the endothelium, it appears to become pro-inflammatory and inhibit them.
 

NP-Based Program Helps Control CKD Cardiac Risk Factors

July 18, 2011

PRAGUE—A multifactorial intervention using a polydrug and lifestyle treatment strategy with nurse practitioner (NP) support can improve management of some cardiovascular (CV) risk factors and reduced the number of physician visits by patients with chronic kidney disease (CKD).
 

Paricalcitol Superior for Lowering iPTH

July 18, 2011

The drug was more likely than cinacalcet to achieve a 50 percent or greater decrease in iPTH from baseline.
 

FDA Recommend More Conservative Dosing of ESAs

July 13, 2011

The FDA is calling for more conservative dosing of erythropoiesis-stimulating agents (ESAs) when used to treat anemia in CKD patients due to the increased risks of cardiovascular events such as stroke, thrombosis, and death.
 

FGF-23, Mortality Linked Even in Early-Stage CKD

July 12, 2011

Elevated levels of fibroblast growth factor 23 (FGF-23) is an independent risk factor for end-stage renal disease (ESRD) in patients with relatively preserved kidney function and for mortality across the spectrum of chronic kidney disease (CKD).
 

Plant-Based Diets May Need to Be Reconsidered

July 11, 2011

A new paradigm may be needed whereby plant-based or vegetarian diets are promoted to preserve GFR and maintain phosphorus homeostasis in CKD patients.
 

FDA Mulling Once-Monthly Anemia Drug

July 06, 2011

The FDA is reviewing a New Drug Application for peginesatide as a treatment for anemia associated with chronic renal failure in adult dialysis patients.
 

Drug Improves Renal Function in Diabetic CKD Patients

July 01, 2011

An experimental anti-inflammatory agent called bardoxolone methyl improves renal function in CKD patients with type 2 diabetes, according to researchers
 

Cause-Specific Outcomes Associated with Hypovitaminosis D

By Csaba P. Kovesdy, MD July 01, 2011

The complex biological actions of vitamin D suggest its involvement in various pathologies. (This is the second of a two-part CME article.)
 

Diabetes Drug Works Despite Renal Damage

June 30, 2011

SAN DIEGO—Linagliptin, a dipeptidyl peptidase (DPP)-4 inhibitor, appears to be a good treatment option for patients with type 2 diabetes and severe renal impairment, researchers announced at the 71st Scientific Sessions of the American Diabetes Association.
 

No Higher Death Risk with a Later Dialysis Start

June 27, 2011

PRAGUE—Early referral patients who start dialysis with an estimated glomerular filtration rate (eGFR) below 6 mL/min/1.73 m2 are not at increased risk of death compared with those who start dialysis at an eGFR above 6, a study showed.
 

Short-Course Rituximab Produces Long-Term Remissions of ANCA Vasculitis

June 27, 2011

PRAGUE—A single four-week course of rituximab was as effective as 18 months of standard therapy with daily oral cyclophosphamide (CyP) and azathioprine (AZA) for induction and maintenance of remission in patients with severe anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). For either treatment, the number, rate, and severity of adverse events did not differ.
 

New Findings Confirm Bardoxolone's Efficacy

June 24, 2011

PRAGUE—Therapy with bardoxolone, an oral antioxidant inflammation modulator, is associated with improved kidney function out to one year in patients with advanced chronic kidney disease (CKD) and type 2 diabetes, according to investigators.
 

ACE Inhibitor Reduces ESRD Risk Among Obese Patients

June 16, 2011

Ramipril can essentially abolish the excess risk for end-stage renal disease (ESRD) seen in obese persons with chronic kidney disease (CKD), according to a post hoc analysis of the Ramipril Efficacy in Nephropathy (REIN) trial.
 

Vitamin D and Clinical Outcomes in Patients With and Without CKD: Part I

By Csaba P. Kovesdy, MD June 01, 2011

Research has shown that vitamin D deficiency has a role in the progressive loss of kidney function as well as increased mortality.
 

High Uric Acid Predicts Albuminuria

May 19, 2011

VANCOUVER, B.C.—Elevated serum uric acid levels strongly predict development of albuminuria in patients with chronic kidney disease (CKD), according to researchers in Romania.
 

U.S. Medical Students Avoiding Nephrology

May 11, 2011

Interest in nephrology as a career is declining and has been on the decline for nearly a decade, according to a new study.
 

Carnitine for Chronic Inflammation

May 10, 2011

Data show that carnitine, an inexpensive therapy with little to no adverse effects, can lower C-reactive protein levels.
 

Oral Iron Found to Be the Optimal First Treatment

April 30, 2011

LAS VEGAS—Oral iron is the optimal first treatment strategy for most iron-deficient, anemic chronic kidney disease (CKD) patients not yet on dialysis, based on a recent analysis presented at the National Kidney Foundation's Spring Clinical Meetings.
 

CV Risk Factors Undertreated in High-Risk CKD Patients

April 30, 2011

LAS VEGAS—Modifiable cardiovascular (CV) risk factors remain undertreated in a very high-risk population of patients with chronic kidney disease (CKD), new findings presented at the National Kidney Foundation's Spring Clinical Meetings suggest.
 

Drug Shows Promise for Treating Calciphylaxis

April 30, 2011

LAS VEGAS—Sodium thiosulfate may hold promise as a treatment for calciphylaxis in patients with end-stage renal disease (ESRD), researchers reported here at the National Kidney Foundation's Spring Clinical Meetings.
 

Obesity, Unhealthy Diets, Smoking Raise CKD Risk

April 30, 2011

LAS VEGAS—Obesity, current smoking, and diet are modifiable risk factors for developing chronic kidney disease (CKD), according to study findings presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Bisphosphonates Lower Death Risk Among Women with CKD

April 30, 2011

LAS VEGAS—Bisphosphonate treatment in women with non-dialysis dependent chronic kidney disease (NDD-CKD) is associated with a decreased risk of death, but not of cardiovascular events, according to data presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Larger Doses of Maintenance IV Iron May Cut ESA Requirements

April 30, 2011

LAS VEGAS—Monthly requirements of erythropoiesis-stimulating agents (ESAs) to maintain target hemoglobin levels may be lower with larger doses of maintenance iron, according to data presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Hyperphosphatemia and Anemia Risk Factors in Diabetic Nephropathy Patients

April 30, 2011

LAS VEGAS—Albumunuria, proteinuria, lower estimated glomerular filtration rate (eGFR) in patients with diabetic nephropathy are significantly associated with hyperphosphatemia and anemia, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.
 

Vitamin D Replacement May Lower CV Event Risk

April 29, 2011

LAS VEGAS—Treatment of 25-hydroxyvitamin D (25(OH)D) deficiency with ergocalciferol in patients with moderate chronic kidney disease (CKD) is associated with a significant reduction in the risk of cardiovascular (CV) events, new data presented at the National Kidney Foundation's Spring Clinical Meetings suggest.
 

Switch From Darbepoetin to Epoetin May Be Beneficial

April 29, 2011

LAS VEGAS—Switching anemic pre-dialysis chronic kidney disease (CKD) from darbepoetin to epoetin is associated with longer dosing intervals and lower drug costs, and hemoglobin levels are maintained in the recommended target range, according to a study presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Inpatient Savings May Offset Cinacalcet Costs

April 29, 2011

LAS VEGAS—Inpatient cost savings may offset the costs of patient adherence to cinacalcet therapy, according to study findings presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Study Finds No Link Between FGF-23 and Dietary Phosphorus

April 29, 2011

LAS VEGAS—Fibroblast growth factor 23 (FGF-23) is not significantly associated with dietary phosphorus or urinary phosphorus excretion, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.
 

Transfusion Patterns Among ND-CKD Patients Characterized

April 29, 2011

LAS VEGAS—Blood transfusions are common for non-dialysis chronic kidney disease (ND-CKD) patients with persistent anemia, according to a report presented at the National Kidney Foundation's Spring Clinical Meetings.
 

25(OH)D Replacement Found Ineffective for SHPT

April 28, 2011

LAS VEGAS—Replacing 25-hydroxyvitamin D (25(OH)D) in hemodialysis (HD) patients who are deficient in the vitamin does not result in a significant decrease in intact parathyroid hormone (iPTH) level, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.
 

CKD Patients with Diabetes Experience Disordered Mineral Metabolism Sooner

April 28, 2011

LAS VEGAS—Disordered mineral metabolism starts earlier in the course of chronic kidney disease (CKD) and is more severe in patients with diabetes than in those without diabetes, investigators reported at the National Kidney Foundation's Spring Clinical Meetings.
 

Vitamin D Repletion May Reduce Darbepoetin Requirements

April 28, 2011

LAS VEGAS—Vitamin D repletion in patients with end-stage renal disease maintains hemoglobin (Hb) levels and results in decreased requirement of darbepoetin alfa, according to data presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Lanthanum Carbonate Found to Bind Dietary Phosphorus Better than Sevelamer

April 28, 2011

LAS VEGAS—Lanthanum carbonate binds dietary phosphorus more effectively than sevelamer, researchers reported here at the National Kidney Foundation's Spring Clinical Meetings.
 

Race Not a Factor in Progression to ESRD, Death

April 28, 2011

LAS VEGAS—Race does not appear to affect the likelihood of progression to end-stage renal disease and overall mortality among obese individuals with chronic kidney disease (CKD), according to study findings presented at the National Kidney Foundation's Spring Clinical Meetings.
 

Iron Repletion Does Not Lower Platelet Counts

April 28, 2011

LAS VEGAS—Correction of iron deficiency does not significantly lower platelet counts in patients with chronic kidney disease (CKD), regardless of molecular weight or dose used, investigators reported at the National Kidney Foundation's Spring Clinical Meetings.
 

Cinacalet Effective for Long-Term Management of Post-Tx Hyperparathyroidism

April 28, 2011

LAS VEGAS—Cinacalcet is effective for the long-term management of persistent hyperparathyroidism after renal transplantation, with deleterious impact on kidney function, researchers reported at the National Kidney Foundation's Spring Clinical Meeting.
 

Dosing Intervals of Darbepoetin Alfa May Be Extended in Pre-Dialysis Patients

April 28, 2011

LAS VEGAS—Darbepoetin alfa dosing intervals in pre-dialysis patients with chronic kidney disease (CKD) may be extended beyond the approved one- or two-week frequency, researchers reported at the National Kidney Foundation's Spring Clinical Meetings.
 

CKD Stage 3 Patients Benefit from Extended-Release Niacin

April 28, 2011

LAS VEGAS—New findings presented at the National Kidney Foundation's Spring Clinical Meetings confirm the phosphorus-lowering effects of extended-release niacin in fixed-dose combination with laropiprant (ERN-L) in dyslipidemic patients with stage 3 chronic kidney disease (CKD).
 

Predictive Model for Progression of CKD to Kidney Failure

April 27, 2011

Clinicians may have an important new tool they can use to better predict which patients with chronic kidney disease (CKD) will progress to kidney failure.
 

Depression May Increase Risk of Kidney Failure

April 22, 2011

For the first time, researchers have found that depression may increase the risk of kidney failure.
 

CKD Knowledge Lacking, Survey Found

April 18, 2011

A 34-question knowledge survey administered to 401 adults with chronic kidney disease (CKD) provided to be a reliable and valid instrument for identifying areas of and risk factors for poor renal knowledge among these patients, but it showed that 78% of respondents did not know that the disease may progress with no symptoms.
 

CKD Stage 3 Needs To Be Redefined

April 18, 2011

Nephrologists should rethink the screening level and offer a more conservative and meaningful cutoff level, such as an eGFR of 45.
 

Triple-Marker Approach May Improve Kidney Disease Detection

April 15, 2011

A new diagnostic strategy that includes three markers may significantly improve the detection and treatment of kidney disease, according to findings published online in the Journal of the American Medical Association.
 

Genetic Clues May Help Prevent IgA Nephropathy

April 13, 2011

Researchers have found five regions in the human genome that increase susceptibility to immunoglobulin A (IgA) nephropathy, a major cause of kidney failure worldwide.
 

CAC Score Predicts Cardiac Events in CKD Patients

April 12, 2011

Assessment of coronary artery calcification (CAC) and progression may be useful for earlier management of risk factors for cardiac events in patients with chronic kidney disease (CKD), according to an Italian study.
 

Drug is Renoprotective in Diabetic CKD Patients

April 11, 2011

VANCOUVER, B.C.—Pentoxiphylline (PTF) may slow the rate of renal function decline in patients with diabetes-related chronic kidney disease who are taking drugs that block the renin-angiotensin system (RAS), a Spanish study found.
 

Vitamin D Deficiency Hikes Death Risk in CKD Patients

April 10, 2011

VANCOUVER, B.C.—Deficiency in 25-hydroxyvitamin D [25(OH)D] is independently associated with an increased risk of death from any cause among patients with chronic kidney disease (CKD), according to researchers. In addition, the likelihood of 25(OH)D deficiency increases with body mass index (BMI).
 
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