Central Renal Masses More Likely to Be RCC

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TORONTO—Centrally located renal masses are five times as likely as peripherally located masses to be renal cell carcinoma (RCC), according to researchers.

Researchers at Dalhousie University and Queen Elizabeth II Health Sciences Centre in Halifax, Nova Scotia, analyzed 157 renal masses in patients who underwent treatment for presumed renal cell carcinoma (RCC) based on preoperative imaging. Of these masses, 61 were peripheral, 74 were central, and 22 were hilar.

The investigators, Ross J. Mason, a medical student, and Ricardo A. Rendon, MD, Associate Professor of Urology, defined a central mass as one extending into the kidney in direct contact with or invading the collecting system and/or renal sinus. They defined a hilar mass as one directly against or invading the main renal vessels. The researchers considered all other masses to be peripheral.

Of the 157 masses, 141 (89.8%) turned out to be RCC. Fifty (82%) peripheral masses were RCC versus 71 (95.9%) central masses and 20 (91%) hilar masses, Drs. Mason and Rendon reported here at the Canadian Urological Association annual meeting. Peripheral masses were twice as likely as hilar masses to be benign.

“This information may be utilized when selecting strategies for the management of renal masses presumed to be RCC,” the investigators concluded.

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