Cardiovascular Disease

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced glomerular filtration rate ranked similarly to high total cholesterol as a risk factor for disability-adjusted life years.

Long-term Multivitamin Use Does Not Reduce CVD Risk in Men

Long-term Multivitamin Use Does Not Reduce CVD Risk in Men

Baseline nutritional status does not influence the effect of randomized long-term multivitamin use on major CVD events.

Poor Diet Blamed for Nearly 1 in 2 Heart Disease, Stroke, T2DM Deaths

Poor Diet Blamed for Nearly 1 in 2 Heart Disease, Stroke, T2DM Deaths

The largest numbers of diet-related cardiometabolic deaths were related to high sodium, low nuts/seeds, high processed meats, low seafood omega-3 fats, low vegetables, low fruits, and high SSBs.

High-Dose Vitamin D Monthly Does Not Prevent CVD

High-Dose Vitamin D Monthly Does Not Prevent CVD

The primary outcome of CVD occurred in 303 participants (11.8%) in the vitamin D group and 293 participants (11.5%) in the placebo group.

Genetic Hyperglycemia Ups CAD Risk, Apart From T2DM

Genetic Hyperglycemia Ups CAD Risk, Apart From T2DM

Hyperglycemia from genetics increases the risk of coronary artery disease separately from type 2 diabetes and other CAD risk factors.

Statin Intolerance May Up Risks for Recurrent AMI, CHD

Statin Intolerance May Up Risks for Recurrent AMI, CHD

Statin intolerance was associated with a 36% higher rate of recurrent MI, a 43% higher rate of CHD events, and a 15% lower rate of all-cause mortality.

No Adverse Outcomes Following Bundling

No Adverse Outcomes Following Bundling

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Action taken to mitigate risks associated with ESA use and changes in payment policy did not result in a relative increase in death or major cardiovascular events.

Meds Targeting PCSK9 Lower LDL in High-Risk Patients

Meds Targeting PCSK9 Lower LDL in High-Risk Patients

Both evolocumab and inclisiran reduced the risk of cardiovascular events and lowered LDL cholesterol levels.

Statin Guidance Varies for Black Patients

Statin Guidance Varies for Black Patients

The USPSTF guidelines focus statin recommendations on 38% of high-risk African American individuals at the expense of not recommending treatment in nearly 25% of African Americans.

Erectile Dysfunction Drug May Reduce Post-MI Hospitalization, Death

Erectile Dysfunction Drug May Reduce Post-MI Hospitalization, Death

Men taking PDE5 lowered their risk of hospitalization and mortality after a heart attack by 33%.

No Increased Risks of Stroke, Heart Failure With DPP-4i

No Increased Risks of Stroke, Heart Failure With DPP-4i

In short-term treatment duration, there was no increased risk of myocardial infarction stroke or heart failure using DPP-4i vs SU/TZD.

Early Predialysis Nephrology Care May Prevent CV Events

Early Predialysis Nephrology Care May Prevent CV Events

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Patients with early and frequent nephrology visits before dialysis initiation had about a 10% lower risk for major adverse cardiovascular events.

Non-Rx Herbal Medication Use Common With CVD Patients

Non-Rx Herbal Medication Use Common With CVD Patients

No evidence to determine whether taking herbal medications cause complications among patients with CVD.

Safe Use of MRI Possible for Pacemaker, ICD Users

Safe Use of MRI Possible for Pacemaker, ICD Users

No deaths, lead failures, losses of capture, or ventricular arrhythmias occurred during MRI.

Plasma TMAO May Help Predict Cardiovascular Mortality Risk

Plasma TMAO May Help Predict Cardiovascular Mortality Risk

Plasma TMAO levels among patients predict both near- and long-term risks of incident cardiovascular events.

High Triglycerides, Low HDL-C Increase CHD, Stroke Risks

High Triglycerides, Low HDL-C Increase CHD, Stroke Risks

Participants with high TG and low HDL levels had a 1.32-fold greater HR for CHD than those with normal TG and normal HDL levels.

Testosterone Replacement May Lower Cardiovascular Risks

Testosterone Replacement May Lower Cardiovascular Risks

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In a large study, testosterone replacement therapy was associated with a 33% lower risk of cardiac and stroke events among hypogonadal men.

Any Coronary Artery Calcium in 30s and 40s Ups Cardiovascular Risks

Any Coronary Artery Calcium in 30s and 40s Ups Cardiovascular Risks

The presence of CAC among individuals aged between 32 and 46 years was associated with increased risk of fatal and nonfatal CHD during 12.5 years of follow-up.

Alcohol Abuse Ups Risk of MI, Heart Failure, AFib

Alcohol Abuse Ups Risk of MI, Heart Failure, AFib

Those without traditional cardiovascular risk factors are disproportionately prone to these cardiac diseases in the setting of alcohol abuse.

More Patients Hospitalized for Atrial Fibrillation

More Patients Hospitalized for Atrial Fibrillation

Adjusted rates of hospitalization for AF increased by almost 1% per year between 1999 and 2013.

Eating Pattern May Affect Cardiovascular Risk

Eating Pattern May Affect Cardiovascular Risk

Irregular eating patterns appear less favorable for achieving a healthy cardiometabolic profile.

No New Adverse Events With Alirocumab, Very Low LDL-C

No New Adverse Events With Alirocumab, Very Low LDL-C

Baseline LDL-C was lower in patients with LDL-C <25 versus ≥25 mg/dl.

Kidney Function Predicts Hospital Discharge, Mortality After Stroke

Kidney Function Predicts Hospital Discharge, Mortality After Stroke

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Patients with an eGFR below 60 mL/min/1.73 m2 were more likely to die in the hospital or be discharged to hospice.

Higher Resting Heart Rate Riskier for Older Adults

Higher Resting Heart Rate Riskier for Older Adults

Higher RHR was significantly associated with all-cause mortality and cardiovascular events in older but not younger participants.

Red Yeast Rice May Pose Similar Risks to Statins

Red Yeast Rice May Pose Similar Risks to Statins

The potential safety signals of myopathies and liver injury raise the hypothesis that the safety profile of RYR is similar to that of statins.

Off-Target CKD-MBD Biomarkers Prognostic for Adverse Outcomes

Off-Target CKD-MBD Biomarkers Prognostic for Adverse Outcomes

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Dialysis facilities with the least control of PTH, Ca, and P had the greatest risks.

Sitagliptin OK for Older Type 2 Diabetes Patients With CVD

Sitagliptin OK for Older Type 2 Diabetes Patients With CVD

Sitagliptin did not significantly impact the primary composite, death, heart failure hospitalization, severe hypoglycemia, rates of acute pancreatitis and pancreatic cancer, or serious adverse events.

Higher Systolic BP Target Recommended for Older Patients

Higher Systolic BP Target Recommended for Older Patients

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New guidelines suggest aiming for a systolic pressure less than 150 mm Hg in hypertensive individuals aged 60 or older.

Fenofibrate May Reduce CVD in Statin-Treated T2DM Patients

Fenofibrate May Reduce CVD in Statin-Treated T2DM Patients

The continued observation of heterogeneity of treatment response by baseline lipids suggests that fenofibrate therapy may reduce CVD in patients with diabetes.

More CHD Patients Die of Noncardiovascular Causes, Study Finds

More CHD Patients Die of Noncardiovascular Causes, Study Finds

Mortality was more frequently due to noncardiovascular causes, and predictors of noncardiovascular mortality included factors traditionally associated with cardiovascular mortality.

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