Cardiovascular Disease

Prostate Cancer Hormone Therapy Ups Cardiac Risks

Prostate Cancer Hormone Therapy Ups Cardiac Risks

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Exposure to androgen-deprivation therapy was associated with a nearly 2-fold increased risk of heart failure among men without pre-existing cardiovascular disease.

High Rates of Infective Endocarditis Found Among ESRD Patients

High Rates of Infective Endocarditis Found Among ESRD Patients

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Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.

Less Than 1 in 2 Patients Receives Approval for PCSK9i Rx

Less Than 1 in 2 Patients Receives Approval for PCSK9i Rx

Overall, therapy was received by just 30.9% of those prescribed PCSK9 inhibitors.

Halting Low-Dose Aspirin Increases Cardiovascular Events

Halting Low-Dose Aspirin Increases Cardiovascular Events

Findings in a large study of long-term low-dose aspirin users.

Statin Use Tied With Lower Death Risk in Elderly Men

Statin Use Tied With Lower Death Risk in Elderly Men

The researchers found that over the study period statin use was associated with an 18% lower risk of all-cause mortality and non-significantly lower risk of CVD events and stroke.

Statin, ACEI/ARB Nonadherence Dangerous After Heart Attack

Statin, ACEI/ARB Nonadherence Dangerous After Heart Attack

Adherence to beta-blockers may not be as beneficial to patients after myocardial infarction.

Anagliptin Improves LDL Partly Via ApoB-100 Suppression

Anagliptin Improves LDL Partly Via ApoB-100 Suppression

The results demonstrated a tendency for a decrease in LDL-C level at 24 weeks in the ANA group, and improvement was mediated through the suppression of apoB-100 synthesis.

Exenatide Does Not Increase Cardiovascular Risk in Type 2 Diabetes

Exenatide Does Not Increase Cardiovascular Risk in Type 2 Diabetes

Administration of exenatide in patients with type 2 diabetes at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.

Cardiovascular Drugs Not Tied to Cognitive Impairment

Cardiovascular Drugs Not Tied to Cognitive Impairment

The researchers found that there was no evidence of an independent correlation between impaired cognitive function and antihypertensive use.

No Difference in Cognitive Function With Evolocumab Plus Statins

No Difference in Cognitive Function With Evolocumab Plus Statins

No associations were seen between low-density lipoprotein cholesterol levels and cognitive changes in an exploratory analysis.

Anacetrapib May Reduce Coronary Events

Anacetrapib May Reduce Coronary Events

The use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo.

Many Older Adults With A-Fib Do Not Receive Anticoagulants

Many Older Adults With A-Fib Do Not Receive Anticoagulants

The researchers found that there was an increase in NOAC use over time, warfarin use did not change, and overall anticoagulant use increased.

Retinal Emboli Associated With CVD Risk Factors, Stroke, CKD

Retinal Emboli Associated With CVD Risk Factors, Stroke, CKD

Older age, Indian ethnicity, hypertension, chronic kidney disease, creatinine level, glomerular filtration rate, and history of stroke were associated with prevalent retinal emboli in multivariable-adjusted analysis.

Canakinumab 150 mg Linked With Fewer Recurrent Cardiac Events

Canakinumab 150 mg Linked With Fewer Recurrent Cardiac Events

Canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo.

Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

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In a study, the risk for heart failure was 81% higher among patients who received androgen deprivation therapy.

High Carb Diet Linked With Early Death

High Carb Diet Linked With Early Death

High-carb diets were associated with a 28% increased risk of death vs low-carb diets.

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

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Liraglutide-treated patients were 22% less likely than placebo recipients to experience a composite outcome of renal events.

ApoB May Be Better Biomarker for CVD Events

ApoB May Be Better Biomarker for CVD Events

ApoB is a superior marker of cardiovascular disease risk than LDL-C.

Intensive Blood Pressure-Lowering as Safe as Usual Care

Intensive Blood Pressure-Lowering as Safe as Usual Care

The researchers found patients on intensive blood pressure treatment fared as well as those on standard care.

Rivaroxaban With Aspirin Most Effective in Stable Atherosclerotic Disease

Rivaroxaban With Aspirin Most Effective in Stable Atherosclerotic Disease

Cardiovascular death, stroke, or myocardial infarction occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group.

Visceral to Subcutaneous Fat Ratio Predicts CVD in Diabetes

Visceral to Subcutaneous Fat Ratio Predicts CVD in Diabetes

The addition of V/S ratio to age, eGFR, BNP, antiplatelet agents, and HbA1c significantly improved classification performance for CVD.

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

The six-month cumulative incidence of myocardial infarction was 2.0% and 0.7% in patients with cancer and controls, respectively.

Light to Moderate Alcohol Use May Reduce CVD Deaths

Light to Moderate Alcohol Use May Reduce CVD Deaths

Those who were light or moderate alcohol consumers, compared with lifestyle abstainers, had a reduced risk of all-cause mortality and CVD mortality.

CPAP Does Not Harm Renal Function in OSA, CVD Patients

CPAP Does Not Harm Renal Function in OSA, CVD Patients

The researchers found that after a median period of 4.4 years, the median change in estimated glomerular filtration rate did not differ significantly between the CPAP and usual-care groups.

Decreasing Kidney Function Increases Atrial Fibrillation Risk

Decreasing Kidney Function Increases Atrial Fibrillation Risk

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Atrial fibrillation risk increases as estimated glomerular filtration rate decreases and albuminuria increases, according to a new meta-analysis.

High Sodium Intake Associated With Adverse Cardiac Strain

High Sodium Intake Associated With Adverse Cardiac Strain

The researchers found that estimated sodium intake greater than 3.7 g per day correlated with larger left atrial and left ventricular dimensions.

Depression Following CAD Diagnosis Increases Mortality

Depression Following CAD Diagnosis Increases Mortality

During a mean follow-up of 9.7 years, 40% of patients died; 50% among those with depression vs 38% among those without depression.

Discontinuing Statin Therapy After Stroke Ups Risk of Recurrence

Discontinuing Statin Therapy After Stroke Ups Risk of Recurrence

Discontinuation of statin therapy between 3 and 6 months after an index ischemic stroke was associated with a higher risk of recurrent stroke within one year after statin discontinuation.

Interval Training Reduces CVD Risk in Testicular Cancer Patients

Interval Training Reduces CVD Risk in Testicular Cancer Patients

Compared with usual care, HIIT correlated with a 20% reduction in the prevalence of modifiable CVD risk factors.

Continuing Statins After Adverse Rx May Prevent CV Events

Continuing Statins After Adverse Rx May Prevent CV Events

Continued statin prescriptions after an adverse reaction were associated with a lower incidence of death and cardiovascular events.

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