Cardiovascular Disease

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Addition of CCTA-detected obstructive coronary artery disease to risk factors ups prediction of MACE.

Clonal Hematopoiesis Associated With CHD, Atherosclerosis

Clonal Hematopoiesis Associated With CHD, Atherosclerosis

Participants with CHIP had a four-fold increased risk compared with noncarriers in 2 retrospective case-control cohorts for evaluation of early-onset myocardial infarction.

Replacing Saturated Fats Effective at Reducing CVD Risk

Replacing Saturated Fats Effective at Reducing CVD Risk

A healthy diet should focus on healthy foods rich in nutrients that can help reduce disease risk, like poly- and monounsaturated vegetable oils, nuts, fruits, vegetables, whole grains, fish, and others.

Traditional Chinese Medicine May Treat CVD

Traditional Chinese Medicine May Treat CVD

For patients who can't tolerate or afford hypertension medications, the research suggested some herbal alternatives: tiankuijiangya, zhongfujiangya, jiangyabao, and jiangya.

Psychological Distress Increases Death Risk in Heart Disease

Psychological Distress Increases Death Risk in Heart Disease

Patients suffering from mental distress experienced higher all-cause cardiovascular deaths.

Hypogonadism Ups MetS Risk in Testicular Cancer Patients

Hypogonadism Ups MetS Risk in Testicular Cancer Patients

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Hypogonadal testicular cancer survivors had 15 times higher odds of metabolic syndrome than their eugonadal counterparts.

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

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Anemic patients were 41% and 80% more likely to have coronary artery disease and peripheral artery disease than non-anemic patients.

Long-Term Antiplatelet Tx Tied to Higher Bleeding Risk in Elderly

Long-Term Antiplatelet Tx Tied to Higher Bleeding Risk in Elderly

The researchers found that during 13,509 patient-years of follow-up, 3166 patients had 405 first bleeding events.

Insulin Degludec Noninferior to Glargine for CV Events in T2DM

Insulin Degludec Noninferior to Glargine for CV Events in T2DM

The researchers found that the primary outcome of first occurrence of an adjudicated major cardiovascular event occurred in 8.5% and 9.3% of patients in the degludec and glargine groups, respectively.

Rise in High-intensity Statin Rx After Myocardial Infarction

Rise in High-intensity Statin Rx After Myocardial Infarction

Male sex, filling β-blocker and antiplatelet agent prescriptions, and attending cardiac rehabilitation within 30 days of discharge were factors associated with filling high-intensity statin prescriptions in 2014.

Canagliflozin Lowers Cardiovascular Risks in Type 2 Diabetes Patients

Canagliflozin Lowers Cardiovascular Risks in Type 2 Diabetes Patients

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Study findings suggest that the medication may offer renal protection.

Senior Death Rate Lower at Academic Hospitals

Senior Death Rate Lower at Academic Hospitals

The likelihood of dying within 30 days of being admitted for care was 1.5% lower at major teaching facilities compared with non-teaching hospitals.

Evacetrapib Treatment Does Not Lower CV Events Risk

Evacetrapib Treatment Does Not Lower CV Events Risk

Treatment with evacetrapib did not result in a lower rate of cardiovascular events than placebo among patients with high-risk vascular disease.

Pravastatin for CHD Prevention Questionable for Seniors

Pravastatin for CHD Prevention Questionable for Seniors

The researchers found no significant difference in coronary heart disease event rates among the groups.

Metabolically Healthy Obese Still at Increased Risk of CVD

Metabolically Healthy Obese Still at Increased Risk of CVD

The investigators also found that the risk of cardiovascular disease in obese people rose with the number of metabolic abnormalities.

Muscle Adverse Events in Statin Users Linked to Pt Expectations

Muscle Adverse Events in Statin Users Linked to Pt Expectations

No significant differences were seen between statin users and non-users in the rates of other adverse events.

Many Heart Attack Patients Not Adhering to Statin Regimen

Many Heart Attack Patients Not Adhering to Statin Regimen

Interventions are needed to increase high-intensity statin use and adherence after myocardial infarction.

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced glomerular filtration rate ranked similarly to high total cholesterol as a risk factor for disability-adjusted life years.

Long-term Multivitamin Use Does Not Reduce CVD Risk in Men

Long-term Multivitamin Use Does Not Reduce CVD Risk in Men

Baseline nutritional status does not influence the effect of randomized long-term multivitamin use on major CVD events.

Poor Diet Blamed for Nearly 1 in 2 Heart Disease, Stroke, T2DM Deaths

Poor Diet Blamed for Nearly 1 in 2 Heart Disease, Stroke, T2DM Deaths

The largest numbers of diet-related cardiometabolic deaths were related to high sodium, low nuts/seeds, high processed meats, low seafood omega-3 fats, low vegetables, low fruits, and high SSBs.

Midlife CVD, Stroke Risk Factors Linked With Amyloid Deposits

Midlife CVD, Stroke Risk Factors Linked With Amyloid Deposits

An increasing number of midlife vascular risk factors was significantly associated with elevated amyloid SUVR; this association was not significant for late-life risk factors.

High-Dose Vitamin D Monthly Does Not Prevent CVD

High-Dose Vitamin D Monthly Does Not Prevent CVD

The primary outcome of CVD occurred in 303 participants (11.8%) in the vitamin D group and 293 participants (11.5%) in the placebo group.

Genetic Hyperglycemia Ups CAD Risk, Apart From T2DM

Genetic Hyperglycemia Ups CAD Risk, Apart From T2DM

Hyperglycemia from genetics increases the risk of coronary artery disease separately from type 2 diabetes and other CAD risk factors.

Cardiovascular Events Risk Up With Body-Weight Variability

Cardiovascular Events Risk Up With Body-Weight Variability

Among patients with the highest variation in body weight, the risk of a coronary event, cardiovascular event, death, myocardial infarction, and stroke was increased.

Statin Intolerance May Up Risks for Recurrent AMI, CHD

Statin Intolerance May Up Risks for Recurrent AMI, CHD

Statin intolerance was associated with a 36% higher rate of recurrent MI, a 43% higher rate of CHD events, and a 15% lower rate of all-cause mortality.

No Adverse Outcomes Following Bundling

No Adverse Outcomes Following Bundling

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Action taken to mitigate risks associated with ESA use and changes in payment policy did not result in a relative increase in death or major cardiovascular events.

Meds Targeting PCSK9 Lower LDL in High-Risk Patients

Meds Targeting PCSK9 Lower LDL in High-Risk Patients

Both evolocumab and inclisiran reduced the risk of cardiovascular events and lowered LDL cholesterol levels.

Statin Guidance Varies for Black Patients

Statin Guidance Varies for Black Patients

The USPSTF guidelines focus statin recommendations on 38% of high-risk African American individuals at the expense of not recommending treatment in nearly 25% of African Americans.

Erectile Dysfunction Drug May Reduce Post-MI Hospitalization, Death

Erectile Dysfunction Drug May Reduce Post-MI Hospitalization, Death

Men taking PDE5 lowered their risk of hospitalization and mortality after a heart attack by 33%.

No Increased Risks of Stroke, Heart Failure With DPP-4i

No Increased Risks of Stroke, Heart Failure With DPP-4i

In short-term treatment duration, there was no increased risk of myocardial infarction stroke or heart failure using DPP-4i vs SU/TZD.

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