Cardiovascular Disease (CVD)

Change in Fitness or Fatness Impacts Cardio Risk Factors

February 06, 2012

Positive change in fitness or fatness impacts cholesterol, hypertension, metabolic syndrome

Severe Vitamin D Deficiency Raises Death Risk in Hemodialysis Patients

Jody A. Charnow February 02, 2012

Hemodialysis (HD) patients with severe vitamin D deficiency are more than twice as likely to die from any cause compared with those who have sufficient levels of the vitamin, according to a German study.

Newer Antihypertensive Agents May Be No Better than Diuretics

Rosemary Frei, MSc January 20, 2012

Calcium channel blockers (CCBs) and ACE inhibitors may be no better than diuretics at preventing cardiovascular deaths in patients with hypertension, according to a follow-up study of patients in a seminal antihypertensive trial. In addition, CCBs and ACE inhibitors may increase cardiovascular risks.

Myocardial Infarctions Frequently Unrecognized in Kidney Disease Patients

Jody A. Charnow January 04, 2012

Myocardial infarction (MI) often goes unrecognized in patients with chronic kidney disease (CKD), and it is associated with a significantly increased risk of death, according to researchers.

EPO Resistance May Predict Cardiovascular Events

Jody A. Charnow December 05, 2011

Early identification of erythropoietin (EPO) resistance may help clinicians predict cardiovascular risk in hemodialysis (HD) patients, according to researchers.

No Benefit To Adding Niacin to Statin Rx

Jody A. Charnow December 01, 2011

Adding niacin to statin therapy offers no incremental clinical benefit to patients with atherosclerotic cardiovascular disease and LDL cholesterol levels below 70 mg/dL, according to study findings published in the New England Journal of Medicine (online ahead of print).

Telephone Intervention Can Help Obese Patients Lose Weight

Jill Stein November 16, 2011

ORLANDO—A weight loss program delivered by telephone can be just as effective in obese patients with at least one cardiovascular risk factor as a weight loss program delivered with in-person support, researchers reported at the American Heart Association Scientific Sessions 2011.

Kidney Transplants Fail to Stop Coronary Artery Calcification

Stephan Cho November 02, 2011

Renal transplantation does not stop or reverse coronary artery calcification (CAC), according to researchers.

CVD Varies by Race in CKD Population

Jody A. Charnow November 01, 2011

Researchers who studied a cohort of individuals with mild-to-moderate chronic kidney disease have identified racial differences in the prevalence of self-reported cardiovascular disease (CVD) and indicators of subclinical CVD.

Drug-Eluting Stents Safe for Most Older CKD Patients

Stephan Cho October 20, 2011

Drug-eluting stents are safe to use in older patients undergoing percutaneous coronary interventions regardless of renal function, researchers concluded.

Erectile Dysfunction Helps Identify Silent CAD in Diabetic Men

Jody A. Charnow September 15, 2011

Erectile dysfunction (ED) can improve the effectiveness of screening diabetic men for asymptomatic coronary artery disease (CAD), according to researchers.

Ambulatory BP Predicts Renal and CV Events

Delicia Honen Yard August 15, 2011

In a study of 436 patients with chronic kidney disease not on dialysis (mean age 65.1 years), ambulatory blood pressure (BP) measurements showed risk of both renal and cardiovascular (CV) events to be highest when daytime systolic BP was 135 mm Hg or higher, when diastolic BP was in the highest quintile, and when nighttime systolic BP was 124 mm Hg or higher.

Survival Better with HD than PD in CHF Patients

Daniel M. Keller, PhD July 21, 2011

PRAGUE—For patients with congestive heart failure (CHF) who initiate maintenance dialysis, those starting on peritoneal dialysis (PD) have a significantly greater death risk than those starting on hemodialysis (HD), according to a French study.

PP Declines Predict Worse HD Patient Survival

Daniel M. Keller, PhD July 20, 2011

PRAGUE—Decreases in pulse pressure (PP), and to a lesser extent increases, predict worse survival in the first year for patients new to hemodialysis (HD), new findings suggest. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) changes also are associated with poorer outcomes. These results are consistent across the entire range of blood pressure (BP) and pulse pressure measurements within the first 30 days of starting dialysis.

LDL Lowering Fails to Slow Renal Disease Progression

Daniel M. Keller, PhD July 19, 2011

PRAGUE—Lowering LDL cholesterol (LDL) can prevent or even reverse atherosclerosis, but it does not do the same for the progression of chronic kidney disease (CKD).

Our exclusive coverage of Kidney Week 2011 in Philadelphia includes interviews, videos and noteworthy clinical reports.

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On The Forefront

Boosting Renal Transplantation with Kidney Paired Donation

In the past five to 10 years, researchers have developed several techniques to overcome donor incompatibility, including paired donation. The following case illustrates the collaborative efforts between nephrologists and urologists at the Glickman Urological and Kidney Institute.