Recently, increasing attention focused on mineralocorticoid receptor antagonists (MRAs) in treating chronic kidney disease (CKD).
In healthy people, renal hyperfiltration associated with 37% and 66% increased risk of all-cause and cardiovascular mortality, respectively.
High levels of indoxyl sulfate are associated with a more than 5-fold increased risk of a first heart failure event.
The risk of dying after suffering a hemorrhagic or ischemic stroke is greatest in the first week.
Sildenafil (Viagra) has demonstrated improvement in heart function without any adverse effect on blood pressure.
Low testosterone may increase cardiovascular (CV) risk in middle-aged men with type 2 diabetes.
Study of AV fistula using cardiovascular MRI reveals increased cardiac output, dilation of heart chambers, and deterioration in endothelial function.
The highest tertile of sclerostin level is associated with a 71% decreased risk of cardiovascular death vs. the lowest tertile.
Statin users with diabetes at lower risk of neuropathy, retinopathy, gangrene.
Analysis of self-monitoring, self-titration of meds in patients at high risk of cardiovascular disease.
Overweight or obese adults with risk factors should be referred for intensive behavioral counseling.
Second review shows value in CKD with suspected ACS, limited by variable sensitivity/specificity.
Allopurinol therapy is not associated with beneficial cardiovascular outcomes in gout patients.
The risk of hospitalization for cardiovascular causes is lower, but the risk for infection-related hospitalization is higher.
Evidence of synergistic effect between hemoglobin A1c values and sodium intake.
It is associated with better long-term survival and reduced risk of revascularization and myocardial infarction compared with PCI.