Researchers find no difference between saline and sodium bicarbonate.

Contrast-induced nephropathy (CIN) develops in 11% of emergency department patients who undergo contrast-enhanced CT (CECT), according to a study published in the Clinical Journal of the American Society of Nephrology (2009; published online ahead of print).

A recent study shows that sodium bicarbonate is no better than saline in preventing contrast-induced nephropathy (CIN).

Evidence comes from a study comparing two strategies for preventing contrast-induced nephropathy

Contrast-induced nephropathy (CIN), defined as a rise in serum creatinine greater than 0.5 mg/dL or a level greater than 25% from baseline following use of intravascular contrast media, is increasing.

PLC Medical Systems, Inc., of Franklin, Mass., has received full approval for a U.S. pivotal trial to study the effectiveness of its RenalGuard System and associated therapy in the prevention of contrast-induced nephropathy (CIN).

CHICAGO—Iso-osmolar and low-osmolar contrast agents showed similar nephrotoxicity in a study of patients with impaired renal function undergoing percutaneous coronary intervention (PCI), according to findings presented here at the American College of Cardiology annual meeting.

CHICAGO—Routine use of contrast agents for evaluating chest pain carries a risk of contrast- induced nephropathy (CIN).

WASHINGTON, D.C.—Targeted renal therapy (TRT) involving intrarenal administration of fenoldopam is safe and feasible in patients undergoing angiographic procedures, even in patients at elevated risk of suffering from contrast-induced nephropathy (CIN).

A RECENT meta-analysis supports administration of N-acetylcysteine prophylaxis to prevent contrast-induced nephropathy, especially in high-risk patients. Researchers also noted that the drug is inexpensive and readily available, and has few side effects.