Higher Resting Heart Rate Riskier for Older Adults

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Higher RHR was significantly associated with all-cause mortality and cardiovascular events in older but not younger participants.
Higher RHR was significantly associated with all-cause mortality and cardiovascular events in older but not younger participants.

(HealthDay News) — The effect of resting heart rate (RHR) on all-cause mortality and cardiovascular events varies with age, according to a study published online in the Journal of the American Geriatrics Society.

Kuibao Li, MD, from Capital Medical University in Beijing, and colleagues conducted a prospective cohort study involving 6209 individuals aged 40 years and older without cardiovascular disease at baseline. Participants were interviewed in 1991 using a standard questionnaire to obtain information on demographics, medical history, and lifestyle risk factors. RHR was categorized according to quartiles.

The researchers found that 840 subjects died and 676 experienced a cardiovascular event during a mean follow-up of 8.3 years. In older participants (≥60 years), there was a significant association for higher RHR with all-cause mortality (P trend < 0.001) and cardiovascular events (P trend = 0.002), which was not seen in younger participants (<60 years; both P trend > 0.05). Age had a significant modifying effect on the correlation between RHR and all-cause mortality and cardiovascular events (P interaction < 0.001 and P interaction = 0.002, respectively). After exclusion of individuals who died or had a cardiovascular event during the first 2 years of follow-up the results were similar.

"High RHR appears to be an independent determinant of all-cause mortality and cardiovascular events in older but not younger individuals," the authors write.

Reference

  1. Li K, Yao C, Yang X, Dong L. Effect of Resting Heart Rate on All-Cause Mortality and Cardiovascular Events According to Age. J Am Geriatr Soc. 30 December 2016. doi: 10.1111/jgs.14714

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