Cardiovascular Disease News Archive
Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism
Exposure to androgen-deprivation therapy was associated with a nearly 2-fold increased risk of heart failure among men without pre-existing cardiovascular disease.
Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.
Overall, therapy was received by just 30.9% of those prescribed PCSK9 inhibitors.
Findings in a large study of long-term low-dose aspirin users.
The researchers found that over the study period statin use was associated with an 18% lower risk of all-cause mortality and non-significantly lower risk of CVD events and stroke.
Adherence to beta-blockers may not be as beneficial to patients after myocardial infarction.
The results demonstrated a tendency for a decrease in LDL-C level at 24 weeks in the ANA group, and improvement was mediated through the suppression of apoB-100 synthesis.
Administration of exenatide in patients with type 2 diabetes at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.
The researchers found that there was no evidence of an independent correlation between impaired cognitive function and antihypertensive use.
No associations were seen between low-density lipoprotein cholesterol levels and cognitive changes in an exploratory analysis.
The use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo.
The researchers found that there was an increase in NOAC use over time, warfarin use did not change, and overall anticoagulant use increased.
Older age, Indian ethnicity, hypertension, chronic kidney disease, creatinine level, glomerular filtration rate, and history of stroke were associated with prevalent retinal emboli in multivariable-adjusted analysis.
Canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo.
In a study, the risk for heart failure was 81% higher among patients who received androgen deprivation therapy.
High-carb diets were associated with a 28% increased risk of death vs low-carb diets.
Liraglutide-treated patients were 22% less likely than placebo recipients to experience a composite outcome of renal events.
ApoB is a superior marker of cardiovascular disease risk than LDL-C.
The researchers found patients on intensive blood pressure treatment fared as well as those on standard care.
Cardiovascular death, stroke, or myocardial infarction occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group.
The addition of V/S ratio to age, eGFR, BNP, antiplatelet agents, and HbA1c significantly improved classification performance for CVD.
The six-month cumulative incidence of myocardial infarction was 2.0% and 0.7% in patients with cancer and controls, respectively.
Those who were light or moderate alcohol consumers, compared with lifestyle abstainers, had a reduced risk of all-cause mortality and CVD mortality.
The researchers found that after a median period of 4.4 years, the median change in estimated glomerular filtration rate did not differ significantly between the CPAP and usual-care groups.
Atrial fibrillation risk increases as estimated glomerular filtration rate decreases and albuminuria increases, according to a new meta-analysis.
The researchers found that estimated sodium intake greater than 3.7 g per day correlated with larger left atrial and left ventricular dimensions.
During a mean follow-up of 9.7 years, 40% of patients died; 50% among those with depression vs 38% among those without depression.
Discontinuation of statin therapy between 3 and 6 months after an index ischemic stroke was associated with a higher risk of recurrent stroke within one year after statin discontinuation.
Compared with usual care, HIIT correlated with a 20% reduction in the prevalence of modifiable CVD risk factors.
Continued statin prescriptions after an adverse reaction were associated with a lower incidence of death and cardiovascular events.
Addition of CCTA-detected obstructive coronary artery disease to risk factors ups prediction of MACE.
Participants with CHIP had a four-fold increased risk compared with noncarriers in 2 retrospective case-control cohorts for evaluation of early-onset myocardial infarction.
A healthy diet should focus on healthy foods rich in nutrients that can help reduce disease risk, like poly- and monounsaturated vegetable oils, nuts, fruits, vegetables, whole grains, fish, and others.
For patients who can't tolerate or afford hypertension medications, the research suggested some herbal alternatives: tiankuijiangya, zhongfujiangya, jiangyabao, and jiangya.
Patients suffering from mental distress experienced higher all-cause cardiovascular deaths.
Hypogonadal testicular cancer survivors had 15 times higher odds of metabolic syndrome than their eugonadal counterparts.
Anemic patients were 41% and 80% more likely to have coronary artery disease and peripheral artery disease than non-anemic patients.
The researchers found that during 13,509 patient-years of follow-up, 3166 patients had 405 first bleeding events.
The researchers found that the primary outcome of first occurrence of an adjudicated major cardiovascular event occurred in 8.5% and 9.3% of patients in the degludec and glargine groups, respectively.
Male sex, filling β-blocker and antiplatelet agent prescriptions, and attending cardiac rehabilitation within 30 days of discharge were factors associated with filling high-intensity statin prescriptions in 2014.
Study findings suggest that the medication may offer renal protection.
The likelihood of dying within 30 days of being admitted for care was 1.5% lower at major teaching facilities compared with non-teaching hospitals.
Treatment with evacetrapib did not result in a lower rate of cardiovascular events than placebo among patients with high-risk vascular disease.
The researchers found no significant difference in coronary heart disease event rates among the groups.
The investigators also found that the risk of cardiovascular disease in obese people rose with the number of metabolic abnormalities.
No significant differences were seen between statin users and non-users in the rates of other adverse events.
Interventions are needed to increase high-intensity statin use and adherence after myocardial infarction.
Reduced glomerular filtration rate ranked similarly to high total cholesterol as a risk factor for disability-adjusted life years.
Baseline nutritional status does not influence the effect of randomized long-term multivitamin use on major CVD events.
The largest numbers of diet-related cardiometabolic deaths were related to high sodium, low nuts/seeds, high processed meats, low seafood omega-3 fats, low vegetables, low fruits, and high SSBs.
An increasing number of midlife vascular risk factors was significantly associated with elevated amyloid SUVR; this association was not significant for late-life risk factors.
The primary outcome of CVD occurred in 303 participants (11.8%) in the vitamin D group and 293 participants (11.5%) in the placebo group.
Hyperglycemia from genetics increases the risk of coronary artery disease separately from type 2 diabetes and other CAD risk factors.
Among patients with the highest variation in body weight, the risk of a coronary event, cardiovascular event, death, myocardial infarction, and stroke was increased.
Statin intolerance was associated with a 36% higher rate of recurrent MI, a 43% higher rate of CHD events, and a 15% lower rate of all-cause mortality.
Action taken to mitigate risks associated with ESA use and changes in payment policy did not result in a relative increase in death or major cardiovascular events.
Both evolocumab and inclisiran reduced the risk of cardiovascular events and lowered LDL cholesterol levels.
The USPSTF guidelines focus statin recommendations on 38% of high-risk African American individuals at the expense of not recommending treatment in nearly 25% of African Americans.
Men taking PDE5 lowered their risk of hospitalization and mortality after a heart attack by 33%.
In short-term treatment duration, there was no increased risk of myocardial infarction stroke or heart failure using DPP-4i vs SU/TZD.
Overweight or obesity increases cardiometabolic risk, but the number and type of CRFs varied substantially by age, even among participants with morbid obesity.
Patients with early and frequent nephrology visits before dialysis initiation had about a 10% lower risk for major adverse cardiovascular events.
No evidence to determine whether taking herbal medications cause complications among patients with CVD.
No deaths, lead failures, losses of capture, or ventricular arrhythmias occurred during MRI.
Plasma TMAO levels among patients predict both near- and long-term risks of incident cardiovascular events.
Participants with high TG and low HDL levels had a 1.32-fold greater HR for CHD than those with normal TG and normal HDL levels.
In a large study, testosterone replacement therapy was associated with a 33% lower risk of cardiac and stroke events among hypogonadal men.
The presence of CAC among individuals aged between 32 and 46 years was associated with increased risk of fatal and nonfatal CHD during 12.5 years of follow-up.
Those without traditional cardiovascular risk factors are disproportionately prone to these cardiac diseases in the setting of alcohol abuse.
Adjusted rates of hospitalization for AF increased by almost 1% per year between 1999 and 2013.
Irregular eating patterns appear less favorable for achieving a healthy cardiometabolic profile.
Baseline LDL-C was lower in patients with LDL-C <25 versus ≥25 mg/dl.
Patients with an eGFR below 60 mL/min/1.73 m2 were more likely to die in the hospital or be discharged to hospice.
Higher RHR was significantly associated with all-cause mortality and cardiovascular events in older but not younger participants.
The potential safety signals of myopathies and liver injury raise the hypothesis that the safety profile of RYR is similar to that of statins.
Dialysis facilities with the least control of PTH, Ca, and P had the greatest risks.
Sitagliptin did not significantly impact the primary composite, death, heart failure hospitalization, severe hypoglycemia, rates of acute pancreatitis and pancreatic cancer, or serious adverse events.
New guidelines suggest aiming for a systolic pressure less than 150 mm Hg in hypertensive individuals aged 60 or older.
The continued observation of heterogeneity of treatment response by baseline lipids suggests that fenofibrate therapy may reduce CVD in patients with diabetes.
Mortality was more frequently due to noncardiovascular causes, and predictors of noncardiovascular mortality included factors traditionally associated with cardiovascular mortality.
The findings indicate that it's not only how much and how often, but also what type of exercise you do that seems to make the difference.
People with an irregular heartbeat should probably drink no more than 1 alcoholic drink per day with 2 alcohol-free days a week.
The researchers found that 710 participants had scores that identified them as anxious about their health, and over the years, 234 participants developed IHD.
People with the slowest heart rate recovery were 2.3 times more likely to die during the study period versus those in the fastest recovery quartile.
Survival rates were 12.9% among patients who received epinephrine within 5 minutes of cardiac arrest.
Cancer survivors did not have a higher risk of STEMI-related mortality; however, they were more than 3 times more likely to die of non-heart-related causes.
The researchers found that high-sensitivity cardiac troponin I levels were significantly higher in participants with erectile dysfunction than in those without
PPIs were associated with an increased overall stroke risk of 21%.
People with no signs, symptoms, or history of cardiovascular disease can still be at risk for having a heart attack or stroke.
Cardiovascular events more than tripled 4 days following the last dialysis session.
Among patients rehospitalized for UA or unplanned revascularization, worse one-year angina and quality-of-life outcomes were seen.
High-intensity statins were associated with a significant survival advantage compared with moderate-intensity statins, even among older adults.
Cancer patients diagnosed in their teens had a more than 4-fold higher risk of death from cardiac disease than patients who didn't have cancer.
The findings suggest that living in a polluted environment could promote development of hypertension, cardiovascular disease, and stroke.
For children aged 1 to 2 years, screening is available at routine child immunization visits.
The authors noted that calcium supplements do have side effects, and they urged people to take moderate supplement doses if their diets are deficient in calcium.
TMAO, a pro-atherogenic metabolite formed by gut microbes, predicts long-term adverse event risk and possible mortality in patients with PAD.
Many of the interactions between statins and other heart drugs are minor, but there are some drug combinations that should be avoided.
On average, AMI over 2 times more likely in the hour after a bout of intense emotions or activity.
Renal and Urology News Articles
- Tamsulosin Improves Clearance of Large Distal Ureteral Stones
- Post-Parathyroidectomy Calcium Requirement Linked to Preop ALP
- Sucroferric Oxyhydroxide Efficacy Similar to That of Sevelamer
- Calciphylaxis in CKD Patients Linked to Hypercoagulable Conditions
- Kidney Cancer Bone Metastasis Predictors Id'd
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