Cardiovascular Disease News Archive

Bleeding, Death Similar for DOAC vs Warfarin in VTE

Bleeding, Death Similar for DOAC vs Warfarin in VTE

Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism

Prostate Cancer Hormone Therapy Ups Cardiac Risks

Prostate Cancer Hormone Therapy Ups Cardiac Risks

Exposure to androgen-deprivation therapy was associated with a nearly 2-fold increased risk of heart failure among men without pre-existing cardiovascular disease.

High Rates of Infective Endocarditis Found Among ESRD Patients

High Rates of Infective Endocarditis Found Among ESRD Patients

Hemodialysis patients had higher rates of infective endocarditis than peritoneal dialysis and kidney transplant patients.

Less Than 1 in 2 Patients Receives Approval for PCSK9i Rx

Less Than 1 in 2 Patients Receives Approval for PCSK9i Rx

Overall, therapy was received by just 30.9% of those prescribed PCSK9 inhibitors.

Halting Low-Dose Aspirin Increases Cardiovascular Events

Halting Low-Dose Aspirin Increases Cardiovascular Events

Findings in a large study of long-term low-dose aspirin users.

Statin Use Tied With Lower Death Risk in Elderly Men

Statin Use Tied With Lower Death Risk in Elderly Men

The researchers found that over the study period statin use was associated with an 18% lower risk of all-cause mortality and non-significantly lower risk of CVD events and stroke.

Statin, ACEI/ARB Nonadherence Dangerous After Heart Attack

Statin, ACEI/ARB Nonadherence Dangerous After Heart Attack

Adherence to beta-blockers may not be as beneficial to patients after myocardial infarction.

Anagliptin Improves LDL Partly Via ApoB-100 Suppression

Anagliptin Improves LDL Partly Via ApoB-100 Suppression

The results demonstrated a tendency for a decrease in LDL-C level at 24 weeks in the ANA group, and improvement was mediated through the suppression of apoB-100 synthesis.

Exenatide Does Not Increase Cardiovascular Risk in Type 2 Diabetes

Exenatide Does Not Increase Cardiovascular Risk in Type 2 Diabetes

Administration of exenatide in patients with type 2 diabetes at a wide range of cardiovascular risk appeared not to cause an increase in their overall cardiovascular risk.

Cardiovascular Drugs Not Tied to Cognitive Impairment

Cardiovascular Drugs Not Tied to Cognitive Impairment

The researchers found that there was no evidence of an independent correlation between impaired cognitive function and antihypertensive use.

No Difference in Cognitive Function With Evolocumab Plus Statins

No Difference in Cognitive Function With Evolocumab Plus Statins

No associations were seen between low-density lipoprotein cholesterol levels and cognitive changes in an exploratory analysis.

Anacetrapib May Reduce Coronary Events

Anacetrapib May Reduce Coronary Events

The use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo.

Many Older Adults With A-Fib Do Not Receive Anticoagulants

Many Older Adults With A-Fib Do Not Receive Anticoagulants

The researchers found that there was an increase in NOAC use over time, warfarin use did not change, and overall anticoagulant use increased.

Retinal Emboli Associated With CVD Risk Factors, Stroke, CKD

Retinal Emboli Associated With CVD Risk Factors, Stroke, CKD

Older age, Indian ethnicity, hypertension, chronic kidney disease, creatinine level, glomerular filtration rate, and history of stroke were associated with prevalent retinal emboli in multivariable-adjusted analysis.

Canakinumab 150 mg Linked With Fewer Recurrent Cardiac Events

Canakinumab 150 mg Linked With Fewer Recurrent Cardiac Events

Canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo.

Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

Prostate Cancer ADT Linked With Cardiovascular Risks, Depression

In a study, the risk for heart failure was 81% higher among patients who received androgen deprivation therapy.

High Carb Diet Linked With Early Death

High Carb Diet Linked With Early Death

High-carb diets were associated with a 28% increased risk of death vs low-carb diets.

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

Liraglutide-treated patients were 22% less likely than placebo recipients to experience a composite outcome of renal events.

ApoB May Be Better Biomarker for CVD Events

ApoB May Be Better Biomarker for CVD Events

ApoB is a superior marker of cardiovascular disease risk than LDL-C.

Intensive Blood Pressure-Lowering as Safe as Usual Care

Intensive Blood Pressure-Lowering as Safe as Usual Care

The researchers found patients on intensive blood pressure treatment fared as well as those on standard care.

Rivaroxaban With Aspirin Most Effective in Stable Atherosclerotic Disease

Rivaroxaban With Aspirin Most Effective in Stable Atherosclerotic Disease

Cardiovascular death, stroke, or myocardial infarction occurred in fewer patients in the rivaroxaban-plus-aspirin group than in the aspirin-alone group.

Visceral to Subcutaneous Fat Ratio Predicts CVD in Diabetes

Visceral to Subcutaneous Fat Ratio Predicts CVD in Diabetes

The addition of V/S ratio to age, eGFR, BNP, antiplatelet agents, and HbA1c significantly improved classification performance for CVD.

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

Short-term Arterial Thromboembolism Risk Elevated in Cancer Patients

The six-month cumulative incidence of myocardial infarction was 2.0% and 0.7% in patients with cancer and controls, respectively.

Light to Moderate Alcohol Use May Reduce CVD Deaths

Light to Moderate Alcohol Use May Reduce CVD Deaths

Those who were light or moderate alcohol consumers, compared with lifestyle abstainers, had a reduced risk of all-cause mortality and CVD mortality.

CPAP Does Not Harm Renal Function in OSA, CVD Patients

CPAP Does Not Harm Renal Function in OSA, CVD Patients

The researchers found that after a median period of 4.4 years, the median change in estimated glomerular filtration rate did not differ significantly between the CPAP and usual-care groups.

Decreasing Kidney Function Increases Atrial Fibrillation Risk

Decreasing Kidney Function Increases Atrial Fibrillation Risk

Atrial fibrillation risk increases as estimated glomerular filtration rate decreases and albuminuria increases, according to a new meta-analysis.

High Sodium Intake Associated With Adverse Cardiac Strain

High Sodium Intake Associated With Adverse Cardiac Strain

The researchers found that estimated sodium intake greater than 3.7 g per day correlated with larger left atrial and left ventricular dimensions.

Depression Following CAD Diagnosis Increases Mortality

Depression Following CAD Diagnosis Increases Mortality

During a mean follow-up of 9.7 years, 40% of patients died; 50% among those with depression vs 38% among those without depression.

Discontinuing Statin Therapy After Stroke Ups Risk of Recurrence

Discontinuing Statin Therapy After Stroke Ups Risk of Recurrence

Discontinuation of statin therapy between 3 and 6 months after an index ischemic stroke was associated with a higher risk of recurrent stroke within one year after statin discontinuation.

Interval Training Reduces CVD Risk in Testicular Cancer Patients

Interval Training Reduces CVD Risk in Testicular Cancer Patients

Compared with usual care, HIIT correlated with a 20% reduction in the prevalence of modifiable CVD risk factors.

Continuing Statins After Adverse Rx May Prevent CV Events

Continuing Statins After Adverse Rx May Prevent CV Events

Continued statin prescriptions after an adverse reaction were associated with a lower incidence of death and cardiovascular events.

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Coronary CT Helps Predict CV Events in Type 2 Diabetes

Addition of CCTA-detected obstructive coronary artery disease to risk factors ups prediction of MACE.

Clonal Hematopoiesis Associated With CHD, Atherosclerosis

Clonal Hematopoiesis Associated With CHD, Atherosclerosis

Participants with CHIP had a four-fold increased risk compared with noncarriers in 2 retrospective case-control cohorts for evaluation of early-onset myocardial infarction.

Replacing Saturated Fats Effective at Reducing CVD Risk

Replacing Saturated Fats Effective at Reducing CVD Risk

A healthy diet should focus on healthy foods rich in nutrients that can help reduce disease risk, like poly- and monounsaturated vegetable oils, nuts, fruits, vegetables, whole grains, fish, and others.

Traditional Chinese Medicine May Treat CVD

Traditional Chinese Medicine May Treat CVD

For patients who can't tolerate or afford hypertension medications, the research suggested some herbal alternatives: tiankuijiangya, zhongfujiangya, jiangyabao, and jiangya.

Psychological Distress Increases Death Risk in Heart Disease

Psychological Distress Increases Death Risk in Heart Disease

Patients suffering from mental distress experienced higher all-cause cardiovascular deaths.

Hypogonadism Ups MetS Risk in Testicular Cancer Patients

Hypogonadism Ups MetS Risk in Testicular Cancer Patients

Hypogonadal testicular cancer survivors had 15 times higher odds of metabolic syndrome than their eugonadal counterparts.

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

Anemic patients were 41% and 80% more likely to have coronary artery disease and peripheral artery disease than non-anemic patients.

Long-Term Antiplatelet Tx Tied to Higher Bleeding Risk in Elderly

Long-Term Antiplatelet Tx Tied to Higher Bleeding Risk in Elderly

The researchers found that during 13,509 patient-years of follow-up, 3166 patients had 405 first bleeding events.

Insulin Degludec Noninferior to Glargine for CV Events in T2DM

Insulin Degludec Noninferior to Glargine for CV Events in T2DM

The researchers found that the primary outcome of first occurrence of an adjudicated major cardiovascular event occurred in 8.5% and 9.3% of patients in the degludec and glargine groups, respectively.

Rise in High-intensity Statin Rx After Myocardial Infarction

Rise in High-intensity Statin Rx After Myocardial Infarction

Male sex, filling β-blocker and antiplatelet agent prescriptions, and attending cardiac rehabilitation within 30 days of discharge were factors associated with filling high-intensity statin prescriptions in 2014.

Canagliflozin Lowers Cardiovascular Risks in Type 2 Diabetes Patients

Canagliflozin Lowers Cardiovascular Risks in Type 2 Diabetes Patients

Study findings suggest that the medication may offer renal protection.

Senior Death Rate Lower at Academic Hospitals

Senior Death Rate Lower at Academic Hospitals

The likelihood of dying within 30 days of being admitted for care was 1.5% lower at major teaching facilities compared with non-teaching hospitals.

Evacetrapib Treatment Does Not Lower CV Events Risk

Evacetrapib Treatment Does Not Lower CV Events Risk

Treatment with evacetrapib did not result in a lower rate of cardiovascular events than placebo among patients with high-risk vascular disease.

Pravastatin for CHD Prevention Questionable for Seniors

Pravastatin for CHD Prevention Questionable for Seniors

The researchers found no significant difference in coronary heart disease event rates among the groups.

Metabolically Healthy Obese Still at Increased Risk of CVD

Metabolically Healthy Obese Still at Increased Risk of CVD

The investigators also found that the risk of cardiovascular disease in obese people rose with the number of metabolic abnormalities.

Muscle Adverse Events in Statin Users Linked to Pt Expectations

Muscle Adverse Events in Statin Users Linked to Pt Expectations

No significant differences were seen between statin users and non-users in the rates of other adverse events.

Many Heart Attack Patients Not Adhering to Statin Regimen

Many Heart Attack Patients Not Adhering to Statin Regimen

Interventions are needed to increase high-intensity statin use and adherence after myocardial infarction.

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced Kidney Function a Major Cause of Cardiovascular Deaths

Reduced glomerular filtration rate ranked similarly to high total cholesterol as a risk factor for disability-adjusted life years.

Long-term Multivitamin Use Does Not Reduce CVD Risk in Men

Long-term Multivitamin Use Does Not Reduce CVD Risk in Men

Baseline nutritional status does not influence the effect of randomized long-term multivitamin use on major CVD events.

Poor Diet Blamed for Nearly 1 in 2 Heart Disease, Stroke, T2DM Deaths

Poor Diet Blamed for Nearly 1 in 2 Heart Disease, Stroke, T2DM Deaths

The largest numbers of diet-related cardiometabolic deaths were related to high sodium, low nuts/seeds, high processed meats, low seafood omega-3 fats, low vegetables, low fruits, and high SSBs.

Midlife CVD, Stroke Risk Factors Linked With Amyloid Deposits

Midlife CVD, Stroke Risk Factors Linked With Amyloid Deposits

An increasing number of midlife vascular risk factors was significantly associated with elevated amyloid SUVR; this association was not significant for late-life risk factors.

High-Dose Vitamin D Monthly Does Not Prevent CVD

High-Dose Vitamin D Monthly Does Not Prevent CVD

The primary outcome of CVD occurred in 303 participants (11.8%) in the vitamin D group and 293 participants (11.5%) in the placebo group.

Genetic Hyperglycemia Ups CAD Risk, Apart From T2DM

Genetic Hyperglycemia Ups CAD Risk, Apart From T2DM

Hyperglycemia from genetics increases the risk of coronary artery disease separately from type 2 diabetes and other CAD risk factors.

Cardiovascular Events Risk Up With Body-Weight Variability

Cardiovascular Events Risk Up With Body-Weight Variability

Among patients with the highest variation in body weight, the risk of a coronary event, cardiovascular event, death, myocardial infarction, and stroke was increased.

Statin Intolerance May Up Risks for Recurrent AMI, CHD

Statin Intolerance May Up Risks for Recurrent AMI, CHD

Statin intolerance was associated with a 36% higher rate of recurrent MI, a 43% higher rate of CHD events, and a 15% lower rate of all-cause mortality.

No Adverse Outcomes Following Bundling

No Adverse Outcomes Following Bundling

Action taken to mitigate risks associated with ESA use and changes in payment policy did not result in a relative increase in death or major cardiovascular events.

Meds Targeting PCSK9 Lower LDL in High-Risk Patients

Meds Targeting PCSK9 Lower LDL in High-Risk Patients

Both evolocumab and inclisiran reduced the risk of cardiovascular events and lowered LDL cholesterol levels.

Statin Guidance Varies for Black Patients

Statin Guidance Varies for Black Patients

The USPSTF guidelines focus statin recommendations on 38% of high-risk African American individuals at the expense of not recommending treatment in nearly 25% of African Americans.

Erectile Dysfunction Drug May Reduce Post-MI Hospitalization, Death

Erectile Dysfunction Drug May Reduce Post-MI Hospitalization, Death

Men taking PDE5 lowered their risk of hospitalization and mortality after a heart attack by 33%.

No Increased Risks of Stroke, Heart Failure With DPP-4i

No Increased Risks of Stroke, Heart Failure With DPP-4i

In short-term treatment duration, there was no increased risk of myocardial infarction stroke or heart failure using DPP-4i vs SU/TZD.

Obese Pts May Not Immediately Display Cardiometabolic Risk Factors

Obese Pts May Not Immediately Display Cardiometabolic Risk Factors

Overweight or obesity increases cardiometabolic risk, but the number and type of CRFs varied substantially by age, even among participants with morbid obesity.

Early Predialysis Nephrology Care May Prevent CV Events

Early Predialysis Nephrology Care May Prevent CV Events

Patients with early and frequent nephrology visits before dialysis initiation had about a 10% lower risk for major adverse cardiovascular events.

Non-Rx Herbal Medication Use Common With CVD Patients

Non-Rx Herbal Medication Use Common With CVD Patients

No evidence to determine whether taking herbal medications cause complications among patients with CVD.

Safe Use of MRI Possible for Pacemaker, ICD Users

Safe Use of MRI Possible for Pacemaker, ICD Users

No deaths, lead failures, losses of capture, or ventricular arrhythmias occurred during MRI.

Plasma TMAO May Help Predict Cardiovascular Mortality Risk

Plasma TMAO May Help Predict Cardiovascular Mortality Risk

Plasma TMAO levels among patients predict both near- and long-term risks of incident cardiovascular events.

High Triglycerides, Low HDL-C Increase CHD, Stroke Risks

High Triglycerides, Low HDL-C Increase CHD, Stroke Risks

Participants with high TG and low HDL levels had a 1.32-fold greater HR for CHD than those with normal TG and normal HDL levels.

Testosterone Replacement May Lower Cardiovascular Risks

Testosterone Replacement May Lower Cardiovascular Risks

In a large study, testosterone replacement therapy was associated with a 33% lower risk of cardiac and stroke events among hypogonadal men.

Any Coronary Artery Calcium in 30s and 40s Ups Cardiovascular Risks

Any Coronary Artery Calcium in 30s and 40s Ups Cardiovascular Risks

The presence of CAC among individuals aged between 32 and 46 years was associated with increased risk of fatal and nonfatal CHD during 12.5 years of follow-up.

Alcohol Abuse Ups Risk of MI, Heart Failure, AFib

Alcohol Abuse Ups Risk of MI, Heart Failure, AFib

Those without traditional cardiovascular risk factors are disproportionately prone to these cardiac diseases in the setting of alcohol abuse.

More Patients Hospitalized for Atrial Fibrillation

More Patients Hospitalized for Atrial Fibrillation

Adjusted rates of hospitalization for AF increased by almost 1% per year between 1999 and 2013.

Eating Pattern May Affect Cardiovascular Risk

Eating Pattern May Affect Cardiovascular Risk

Irregular eating patterns appear less favorable for achieving a healthy cardiometabolic profile.

No New Adverse Events With Alirocumab, Very Low LDL-C

No New Adverse Events With Alirocumab, Very Low LDL-C

Baseline LDL-C was lower in patients with LDL-C <25 versus ≥25 mg/dl.

Kidney Function Predicts Hospital Discharge, Mortality After Stroke

Kidney Function Predicts Hospital Discharge, Mortality After Stroke

Patients with an eGFR below 60 mL/min/1.73 m2 were more likely to die in the hospital or be discharged to hospice.

Higher Resting Heart Rate Riskier for Older Adults

Higher Resting Heart Rate Riskier for Older Adults

Higher RHR was significantly associated with all-cause mortality and cardiovascular events in older but not younger participants.

Red Yeast Rice May Pose Similar Risks to Statins

Red Yeast Rice May Pose Similar Risks to Statins

The potential safety signals of myopathies and liver injury raise the hypothesis that the safety profile of RYR is similar to that of statins.

Off-Target CKD-MBD Biomarkers Prognostic for Adverse Outcomes

Off-Target CKD-MBD Biomarkers Prognostic for Adverse Outcomes

Dialysis facilities with the least control of PTH, Ca, and P had the greatest risks.

Sitagliptin OK for Older Type 2 Diabetes Patients With CVD

Sitagliptin OK for Older Type 2 Diabetes Patients With CVD

Sitagliptin did not significantly impact the primary composite, death, heart failure hospitalization, severe hypoglycemia, rates of acute pancreatitis and pancreatic cancer, or serious adverse events.

Higher Systolic BP Target Recommended for Older Patients

Higher Systolic BP Target Recommended for Older Patients

New guidelines suggest aiming for a systolic pressure less than 150 mm Hg in hypertensive individuals aged 60 or older.

Fenofibrate May Reduce CVD in Statin-Treated T2DM Patients

Fenofibrate May Reduce CVD in Statin-Treated T2DM Patients

The continued observation of heterogeneity of treatment response by baseline lipids suggests that fenofibrate therapy may reduce CVD in patients with diabetes.

More CHD Patients Die of Noncardiovascular Causes, Study Finds

More CHD Patients Die of Noncardiovascular Causes, Study Finds

Mortality was more frequently due to noncardiovascular causes, and predictors of noncardiovascular mortality included factors traditionally associated with cardiovascular mortality.

Participation in Specific Sports Tied to Significant Health Benefits

Participation in Specific Sports Tied to Significant Health Benefits

The findings indicate that it's not only how much and how often, but also what type of exercise you do that seems to make the difference.

Moderate Alcohol Can Trigger Atrial Fibrillation

Moderate Alcohol Can Trigger Atrial Fibrillation

People with an irregular heartbeat should probably drink no more than 1 alcoholic drink per day with 2 alcohol-free days a week.

Health Anxiety Ups Ischemic Heart Disease Risk

Health Anxiety Ups Ischemic Heart Disease Risk

The researchers found that 710 participants had scores that identified them as anxious about their health, and over the years, 234 participants developed IHD.

Slow Heart Rate Recovery Linked to Death in Seniors

Slow Heart Rate Recovery Linked to Death in Seniors

People with the slowest heart rate recovery were 2.3 times more likely to die during the study period versus those in the fastest recovery quartile.

Immediate Epinephrine Helps Cardiac Arrest Survival

Immediate Epinephrine Helps Cardiac Arrest Survival

Survival rates were 12.9% among patients who received epinephrine within 5 minutes of cardiac arrest.

Cancer Survivors With STEMI at Increased Risk for Noncardiac Death

Cancer Survivors With STEMI at Increased Risk for Noncardiac Death

Cancer survivors did not have a higher risk of STEMI-related mortality; however, they were more than 3 times more likely to die of non-heart-related causes.

Erectile Dysfunction Associated With Subclinical Myocardial Injury

Erectile Dysfunction Associated With Subclinical Myocardial Injury

The researchers found that high-sensitivity cardiac troponin I levels were significantly higher in participants with erectile dysfunction than in those without

PPIs Linked to Increased Risk of Ischemic Stroke

PPIs Linked to Increased Risk of Ischemic Stroke

PPIs were associated with an increased overall stroke risk of 21%.

Statins Recommended for Adults With No Cardiovascular Disease

Statins Recommended for Adults With No Cardiovascular Disease

People with no signs, symptoms, or history of cardiovascular disease can still be at risk for having a heart attack or stroke.

More Cardiovascular Events Occur After Longer HD Schedule

More Cardiovascular Events Occur After Longer HD Schedule

Cardiovascular events more than tripled 4 days following the last dialysis session.

Rehospitalization After Heart Attack Linked to Worse Health

Rehospitalization After Heart Attack Linked to Worse Health

Among patients rehospitalized for UA or unplanned revascularization, worse one-year angina and quality-of-life outcomes were seen.

High-Intensity Statins May Confer a Survival Advantage

High-Intensity Statins May Confer a Survival Advantage

High-intensity statins were associated with a significant survival advantage compared with moderate-intensity statins, even among older adults.

Age at Cancer Diagnosis Predicts Cardiac Risk

Age at Cancer Diagnosis Predicts Cardiac Risk

Cancer patients diagnosed in their teens had a more than 4-fold higher risk of death from cardiac disease than patients who didn't have cancer.

Young Susceptible to Endothelial Injury From Pollution

Young Susceptible to Endothelial Injury From Pollution

The findings suggest that living in a polluted environment could promote development of hypertension, cardiovascular disease, and stroke.

Pediatric Screening for High Cholesterol Feasible

Pediatric Screening for High Cholesterol Feasible

For children aged 1 to 2 years, screening is available at routine child immunization visits.

No Clear CVD Risk With Calcium Supplements

No Clear CVD Risk With Calcium Supplements

The authors noted that calcium supplements do have side effects, and they urged people to take moderate supplement doses if their diets are deficient in calcium.

Meat Byproduct Linked to Increased Death in PAD Patients

Meat Byproduct Linked to Increased Death in PAD Patients

TMAO, a pro-atherogenic metabolite formed by gut microbes, predicts long-term adverse event risk and possible mortality in patients with PAD.

Statins Can Interact With Other Cardiovascular Drugs

Statins Can Interact With Other Cardiovascular Drugs

Many of the interactions between statins and other heart drugs are minor, but there are some drug combinations that should be avoided.

Anger, Activity Can Trigger Heart Attack

Anger, Activity Can Trigger Heart Attack

On average, AMI over 2 times more likely in the hour after a bout of intense emotions or activity.

Sign Up for Free e-newsletters