Cancer

Polypharmacy More Likely for Cancer Survivors

Polypharmacy More Likely for Cancer Survivors

More cancer survivors prescribed 5 or more unique medications, including those with abuse potential

No Higher Cancer Risk Seen for Heart Failure Patients

No Higher Cancer Risk Seen for Heart Failure Patients

After a median 20 years of follow-up, heart failure not associated with cancer incidence

Most Patients Are Unaware of Cancer Drug Shortages

Most Patients Are Unaware of Cancer Drug Shortages

Majority say they want to know about even minor consequences of cancer drug substitutions

Novel Interstitium Has Been Identified in Human Tissues

Novel Interstitium Has Been Identified in Human Tissues

Structure demonstrated to be part of the submucosa, supported by network of thick collagen bundles

Cancer History Linked to Fatigue

Cancer History Linked to Fatigue

Fatigability and poor endurance significantly higher in older adults with cancer history

Periodontitis May Increase Cancer Risk

Periodontitis May Increase Cancer Risk

Strongest associations found for lung and colorectal cancer

Circulating Tumor DNA Assays of Limited Use for Cancer Screening

Circulating Tumor DNA Assays of Limited Use for Cancer Screening

No evidence for circulating tumor DNA assays in early-stage cancer, residual disease detection

Vitamin D Status Tied With Cancer Risk

Vitamin D Status Tied With Cancer Risk

Inverse correlation for plasma 25-hydroxyvitamin D concentration with total cancer, liver cancer

Commercial Insurers' Coverage of Infused Chemo Varies by Setting

Commercial Insurers' Coverage of Infused Chemo Varies by Setting

Better reimbursement at hospital outpatient depts, even though drug-level costs lower in doctor's office

Mortality Up in Cancer Survivors, Independent of CV Risks

Mortality Up in Cancer Survivors, Independent of CV Risks

Fibrinogen, von Willebrand factor are potential markers of mortality in cancer survivors.

Placebo May Ease Fatigue in Cancer Survivors

Placebo May Ease Fatigue in Cancer Survivors

Reductions seen in fatigue symptom severity and fatigue-related quality of life disruption

Adolescent Cancer Survivors Have Inadequate Follow-up Care

Adolescent Cancer Survivors Have Inadequate Follow-up Care

Many young adult cancer survivors do not follow up properly, independent of disease type or insurance.

Highly Processed Foods Linked to Increased Cancer Risk

Highly Processed Foods Linked to Increased Cancer Risk

10 increase in proportions of ultra-processed foods tied to 10 higher breast and overall cancer risk

Model Stratifies Long Bone Metastases Pts By Survival

Model Stratifies Long Bone Metastases Pts By Survival

Model includes 4 prognostic categories with clinical consequences to predict median survival.

CKD, Diabetes, CVD, and More Boost Risks for Cancer, Mortality

CKD, Diabetes, CVD, and More Boost Risks for Cancer, Mortality

Risk scores summarizing 8 diseases, markers tied to cancer risk in dose-response manner

Cancer Survival Generally Up Worldwide

Cancer Survival Generally Up Worldwide

Increasing trend seen for some lethal cancers, with up to 5% increase for liver, pancreas, lung CAs.

Optimizing Quality of Life in Seniors With Cancer

Optimizing Quality of Life in Seniors With Cancer

Persistent symptoms, comorbidities, leisure-time physical activity, financial challenges deemed key factors

Cancer Deaths Down in the United States

Cancer Deaths Down in the United States

Continuous drop in combined cancer death rate from 1991 to 2015, resulting in 2,378,600 fewer death.

1 in 10 Heart Transplant Pts Develops De Novo Solid Malignancy

1 in 10 Heart Transplant Pts Develops De Novo Solid Malignancy

Higher mortality for heart transplant patients with de novo solid malignancy than those without malignancy.

Few Immuno-Oncology Agents Effective by ASCO Standards

Few Immuno-Oncology Agents Effective by ASCO Standards

Durable survival, response rates rarely recognized as significant by current oncology value frameworks.

Adverse Events Up for Autoimmune Disease Pts on Checkpoint Inhibitors

Adverse Events Up for Autoimmune Disease Pts on Checkpoint Inhibitors

Most patients with cancer, autoimmune disease have improvement in events without discontinuing therapy.

Higher Out-of-Pocket Costs Correlate With Worse Cancer Care

Higher Out-of-Pocket Costs Correlate With Worse Cancer Care

Across cancers, higher costs tied to higher rates of oral prescription abandonment, delayed initiation.

Cancer Treatments Can Have Effects on Aging Phenotypes

Cancer Treatments Can Have Effects on Aging Phenotypes

Certain chemotherapies might shorten telomeres and alter microRNA.

Urologic Cancer Risk Higher in Kidney Failure Patients

Urologic Cancer Risk Higher in Kidney Failure Patients

By

Patients with end-stage renal disease (ESRD) have a 6-fold and 4.4-fold increased risk of kidney cancer and urothelial cancers, respectively, than individuals without ESRD.

Ulixertinib Is Active, Safe for Pts With MAPK Mutant Solid Tumors

Ulixertinib Is Active, Safe for Pts With MAPK Mutant Solid Tumors

ERK1/2 kinase inhibitor, ulixertinib, was used to treat cancer patients with MAPK mutant solid tumors.

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Male patients with mCRPC and seizure risk factors did not have increased seizure incidents when taking Enzalutamide.

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer survival was greatly skewed toward patients with Medicare or private insurance.

Nearly Half of Cancers, Cancer Deaths Possibly Preventable

Nearly Half of Cancers, Cancer Deaths Possibly Preventable

About 45.1% of cancer deaths and 42% of all incident cancers are linked to modifiable risk factors.

Higher Mortality for Native Americans With Certain Cancers

Higher Mortality for Native Americans With Certain Cancers

Comorbidity may be higher in American Indians and Native Alaskans than in non-Hispanic white cancer patients.

Diabetes With High BMI Ups Risk of Some Cancers

Diabetes With High BMI Ups Risk of Some Cancers

The combined effects of high BMI and diabetes resulted in 5.6% of all incident cancers in 2012.

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