Cancer

Cancer Deaths Down in the United States

Cancer Deaths Down in the United States

Continuous drop in combined cancer death rate from 1991 to 2015, resulting in 2,378,600 fewer death.

1 in 10 Heart Transplant Pts Develops De Novo Solid Malignancy

1 in 10 Heart Transplant Pts Develops De Novo Solid Malignancy

Higher mortality for heart transplant patients with de novo solid malignancy than those without malignancy.

Few Immuno-Oncology Agents Effective by ASCO Standards

Few Immuno-Oncology Agents Effective by ASCO Standards

Durable survival, response rates rarely recognized as significant by current oncology value frameworks.

Adverse Events Up for Autoimmune Disease Pts on Checkpoint Inhibitors

Adverse Events Up for Autoimmune Disease Pts on Checkpoint Inhibitors

Most patients with cancer, autoimmune disease have improvement in events without discontinuing therapy.

Higher Out-of-Pocket Costs Correlate With Worse Cancer Care

Higher Out-of-Pocket Costs Correlate With Worse Cancer Care

Across cancers, higher costs tied to higher rates of oral prescription abandonment, delayed initiation.

Cancer Treatments Can Have Effects on Aging Phenotypes

Cancer Treatments Can Have Effects on Aging Phenotypes

Certain chemotherapies might shorten telomeres and alter microRNA.

Urologic Cancer Risk Higher in Kidney Failure Patients

Urologic Cancer Risk Higher in Kidney Failure Patients

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Patients with end-stage renal disease (ESRD) have a 6-fold and 4.4-fold increased risk of kidney cancer and urothelial cancers, respectively, than individuals without ESRD.

Ulixertinib Is Active, Safe for Pts With MAPK Mutant Solid Tumors

Ulixertinib Is Active, Safe for Pts With MAPK Mutant Solid Tumors

ERK1/2 kinase inhibitor, ulixertinib, was used to treat cancer patients with MAPK mutant solid tumors.

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Enzalutamide Does Not Appear to Up Seizures in mCRPC

Male patients with mCRPC and seizure risk factors did not have increased seizure incidents when taking Enzalutamide.

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer Pts With Private Insurance, Medicare May Have Survival Advantage

Cancer survival was greatly skewed toward patients with Medicare or private insurance.

Nearly Half of Cancers, Cancer Deaths Possibly Preventable

Nearly Half of Cancers, Cancer Deaths Possibly Preventable

About 45.1% of cancer deaths and 42% of all incident cancers are linked to modifiable risk factors.

Higher Mortality for Native Americans With Certain Cancers

Higher Mortality for Native Americans With Certain Cancers

Comorbidity may be higher in American Indians and Native Alaskans than in non-Hispanic white cancer patients.

Diabetes With High BMI Ups Risk of Some Cancers

Diabetes With High BMI Ups Risk of Some Cancers

The combined effects of high BMI and diabetes resulted in 5.6% of all incident cancers in 2012.

Swedish Massage May Ease Fatigue in Cancer Patients

Swedish Massage May Ease Fatigue in Cancer Patients

6 weeks Swedish massage therapy significantly decreased cancer-related fatigue in female breast cancer survivors.

Cancer History Common in Newly Diagnosed Patients

Cancer History Common in Newly Diagnosed Patients

About one-fourth of older cancer patients were previously diagnosed.

Coffee Benefits May Outweigh Risks

Coffee Benefits May Outweigh Risks

Coffee consumption was affiliated with more positives than negatives across a wide range of health outcomes.

Warfarin May Decrease Cancer Risk

Warfarin May Decrease Cancer Risk

For this population-based cohort study, researchers analyzed the health outcomes of 1,256,725 patients and separated them into warfarin- and non-warfarin-using subgroups.

Fewer Cancer Patients Are Asked to Quit Smoking

Fewer Cancer Patients Are Asked to Quit Smoking

General practitioners less likely to support smoking cessation in patients with cancer than with CHD

Bleeding, Death Similar for DOAC vs Warfarin in VTE

Bleeding, Death Similar for DOAC vs Warfarin in VTE

Direct oral anticoagulants not linked to increased risk of major bleeding, death in venous thromboembolism

Legal Cannabis Use High Among Cancer Patients in WA

Legal Cannabis Use High Among Cancer Patients in WA

Legalization increases likelihood of use; most want information about the drug from their doctors

Various Neurological Complications Tied to Anti-PD-1 Therapy

Various Neurological Complications Tied to Anti-PD-1 Therapy

The researchers found that 2.9% of the 347 patients treated with anti-PD-1 monoclonal antibodies developed subacute onset of neurological complications.

FDA Approves First Biosimilar for Kidney Cancer Treatment

FDA Approves First Biosimilar for Kidney Cancer Treatment

Mvasi, which is approved to treat colorectal, lung, brain, kidney, and cervical cancer, was found to be biosimilar to the drug Avastin.

AACR Reports Progress in Cancer Care

AACR Reports Progress in Cancer Care

AACR reports that the US cancer death rate has decreased 25% from 1991 to 2014, resulting in 2.1 million fewer cancer-related deaths.

Universal Sequencing of Cancer-related Genes Beneficial for Tx

Universal Sequencing of Cancer-related Genes Beneficial for Tx

Knowledge of these additional mutations can help guide therapeutic and preventive interventions.

Most Melanomas Arise From New Lesions, Not Moles

Most Melanomas Arise From New Lesions, Not Moles

The findings showed that only 29.1% of the skin cancers started in moles patients already had.

Even Slow Weight Gain Ups Hypertension, Diabetes, Cancer Risks

Even Slow Weight Gain Ups Hypertension, Diabetes, Cancer Risks

After 11 pounds gained, the risk of diabetes went up 31%, hypertension 14%, and cardiovascular disease 8%.

Energy Dense Diet Increases Obesity-Related Cancer Risk

Energy Dense Diet Increases Obesity-Related Cancer Risk

The increased risk for obesity-related cancer was seen among women who were normal weight at enrollment.

Occult Cancer Detected in 1 in 20 Unprovoked VTE Patients

Occult Cancer Detected in 1 in 20 Unprovoked VTE Patients

The researchers found that after VTE diagnosis, the 12-month prevalence of cancer was 5.2%.

Cancer Trial Participation Up Under ACA

Cancer Trial Participation Up Under ACA

There were no significant changes in insurer approval rates or referral wait times for patients covered by Medicare or Medicaid.

Early Death Risk Up With Alternative vs Traditional Cancer Care

Early Death Risk Up With Alternative vs Traditional Cancer Care

Evidence suggests that using alternative medicine in place of proven cancer therapies results in worse survival.

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