Some Post-Cystectomy Risks Increase with Older Age, Comorbidities

A prolonged hospital stay and discharge to a nursing facility were among the risks.
A prolonged hospital stay and discharge to a nursing facility were among the risks.

Older patients and those with comorbidities have slower recovery and worse outcomes after radical cystectomy for bladder cancer, according to a study presented at the Canadian Urological Association annual meeting in Ottawa.

For the study, a research team led by Jasmir G. Nayak, MD, of the University of Washington in Seattle, examined outcomes following radical cystectomy for almost 6,500 bladder cancer patients. Following surgery, 37% of patients experienced a prolonged hospital stay of more than 10 days, 16% were discharged to a skilled nursing facility, and 2% died during admission. Among those discharged from the hospital, more than a quarter were readmitted within 2 months.

The likelihood of a prolonged hospital stay or discharge to a nursing facility was linked with older age (above 70) and increasing comorbidities, the researchers found. Mortality was associated with older age and having 3 or more comorbidities. Hospital readmissions were linked with comorbidities, but not age. The researchers adjusted for other relevant factors, such as hospital location, provider volume, and patient marital status.

“These data may inform preoperative patient counseling regarding the potential for prolonged recovery and mortality and facilitate improved shared decision-making between patients and clinicians anticipating cystectomy for bladder cancer,” the researchers concluded in their study abstract. 

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