Obesity, Diabetes Hike Post-Cystectomy Surgical Site Infection Risk

Preoperative weight loss greater than 10% and operative time more than 6 hours also increased the risk.

 A BMI above 30 kg/m2 and diabetes were associated with a significant 42% and 52% increased risk of a surgical site infection, respectively.
A BMI above 30 kg/m2 and diabetes were associated with a significant 42% and 52% increased risk of a surgical site infection, respectively.

High body mass index (BMI) and diabetes are among the patient factors associated with an increased risk of surgical site infections following radical cystectomy, according to data presented at the Canadian Urological Association annual meeting in Ottawa.

Ehab Elzayat, MD, of the University of Ottawa, and colleagues conducted a historical cohort study that included 2,208 radical cystectomy patients, of whom 276 (12.5%) experienced an SSI. The mean time to SSIs was 14.2 days after surgery. A BMI above 30 kg/m2 and diabetes were associated with a significant 42% and 52% increased risk of an SSI, respectively, compared with the absence of these factors. Additionally, the investigators found that preoperative weight loss of more than 10% and an operative time greater than 6 hours were associated with a significant 68% and 73% increased risk of an SSI, respectively.

Of the 276 patients who experienced an SSI, 141 had a superficial infection, 42 had a deep infection, and 95 had an organ/abdominal space infection.

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