Improvement in BMD was seen with denosumab, which also reduced the incidence of new radiographic vertebral fractures in one high-quality trial.
Bone mineral density in the lumbar spine and femoral neck increased over time in hemodialysis patients who underwent total parathyroidectomy without autotransplantation.
Almost 40% of pre-dialysis patients with stage 4-5 CKD patients and type 2 diabetes had lab results suggesting low turnover bone disease.
Among other changes, the new KDIGO guidelines highlight the potential dangers of hypercalcemia.
Researchers using spectral computed tomography found that calcium concentration increased in cortical bone and decreased in cancellous bone.
Bone expression of sclerostin and parathyroid hormone receptor-1 increased in earlier stages of CKD, whereas FGF-23 and phosphorylated b-catenin showed increased expression in later stages.
Alkaline phosphatase was more strongly linked to mortality compared with other biomarkers of chronic kidney disease-mineral and bone disorder.
At 6 months of treatment, bone imaging showed stable disease in 94% of patients with available data, study finds.
Older men on TRT versus placebo for 1 year had improved hemoglobin levels and volumetric bone mineral density and estimated bone strength.
Adipose tissue may be more important than vitamin D intake, new study suggests.
In a study, 94.1% of total PTx patients had improvement of bone mineral density at their most affected site.
Fracture incidence within a year of transplant was 3 times lower among patients who had surgery from 2009 to 2011 vs 2004 to 2006.
Over 33 months, the 25-hydroxyvitamin D level of ergocalciferol recipients increased significantly from 15.14 to 37.32 ng/mL.
Low testosterone levels may be a contributing factor.
SHPT risk was 4 times higher among patients taking furosemide vs hydrochlorothiazide.
The control of phosphorus is underappreciated, for example.
Almost quadruple the risk found among Asian men with erectile dysfunction.
An interview with Neal Shore, MD
High intact parathyroid hormone levels were associated with a lower estimated glomerular filtration rate.
The risk of dying following a hip fracture was 6.5 times higher for patients with severe CKD than for those with normal kidney function or mild CKD.
Fracture risk may be lower with bisphosphonates in women with diabetes.
Very low protein intake was not superior to traditional low protein diets, however.
Researchers find no evidence that increasing calcium intake will prevent fractures.
Even healthy adults show evidence of abnormal bone metabolism.
Hyponatremia is a risk factor for osteoporosis and fracture, a new study confirms.
Large European study identifies ranges of phosphorus, calcium, and parathyroid hormone levels with the lowest death risk.
Prevalence of osteoporosis 16.2% in adults aged 65 years and older; higher among women.
Findings for weight-lifting, jump training in middle-aged men with osteopenia.
No increases seen in bone density, muscle mass, or mobility in postmenopausal women.
Dose-response association noted with increased fracture rates for fruit and vegetable intake below 5 servings/day.
Renal and Urology News Articles
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- Acute Kidney Injury (AKI)
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- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)