Bladder Cancer

More Bladder Cancer Is Metastatic at Diagnosis

Jill Stein July 28, 2010

BARCELONA—Researchers have documented a small but significant stage migration in metastatic bladder cancer between 1988 and 2006.
 

Imaging Agent for Bladder Cancer Okayed

Jody A. Charnow July 27, 2010

The FDA has approved Cysview (hexaminolevulinate HCl), an optical imaging agent indicated for use in the cystoscopic detection of non-muscle-invasive papillary bladder cancer in patients suspected or known to have lesions on the basis of prior cystoscopy.
 

Dye Workers Face Long-Term Bladder Cancer Risk

Jody A. Charnow July 14, 2010

Even 30 or more years after their last exposure to aromatic amines, which are known bladder carcinogens, individuals have an excess risk of bladder cancer, a study found.
 

Benign Prostatic Hyperplasia

BPH Drugs May Enhance Prostate Cancer Detection

Jody A. Charnow June 03, 2010

SAN FRANCISCO—Prostate biopsies performed after treatment with 5-alpha reductase inhibitors increase the rate of prostate cancer detection, researchers reported at the American Urological Association annual meeting.
 

Finasteride May Be a Better Choice for Lower Urinary Tract Symptoms

Jody A. Charnow June 01, 2010

SAN FRANCISCO—Finasteride and dutasteride are similarly effective for treating lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia in properly selected patients, but dutasteride is associated with significantly greater sexual side effects and breast complications, researchers reported.
 

Intraurethral Catheters Recommended

May 01, 2010

They cause fewer UTIs than indwelling catheters in men at high risk during anesthesia and surgery.
 

Erectile Dysfunction

ED Drugs Can Ease Post-Op Urinary Incontinence

Rosemary Frei, MSc September 07, 2010

TORONTO—Use of an oral phosphodiesterase type-5 inhibitor (PDE5i) significantly reduces urinary incontinence after radical prostatectomy (RP), according to data presented at the joint annual meeting of the International Continence Society and the International Urogynecological Association.
 

ED Raises Risk of Calcified Coronary Arteries

Jill Stein July 27, 2010

SAN FRANCISCO—New research implicates erectile dysfunction (ED) as an independent risk factor for high-risk coronary artery calcification.
 

ED Signals Higher Death and Cardiovascular Risk

Delicia Honen Yard May 21, 2010

Erectile dysfunction (ED) is a strong predictor of all-cause mortality and the composite of cardiovascular death, heart attack, stroke, and heart failure in men with cardiovascular disease (CVD), according to the results of a worldwide study of 1,519 men with ED and CVD.
 

Erectile Dysfunction Signals Higher Death and Cardiovascular Risk

Delicia Honen Yard April 09, 2010

Erectile dysfunction (ED) is a strong predictor of all-cause mortality and the composite of cardiovascular death, heart attack, stroke, and heart failure in men with cardiovascular disease (CVD), according to the results of a worldwide study of 1,519 men with ED and CVD.
 

Erectile Dysfunction Levels Off Two Years After EBRT

Delicia Honen Yard March 26, 2010

For men who have had external beam radiotherapy (EBRT) for prostate cancer, the greatest decline in sexual function is in the first 24 months post-treatment, with no significant changes thereafter, according to a report in the International Journal of Radiation Oncology, Biology, Physics (2010;76:31-35).
 

Kidney Cancer

Cryoablation Suitable for Larger Renal Masses

Jody A. Charnow August 10, 2010

Percutaneous cryoablation of larger renal masses can be performed with high technical success and low complication rates, according to researchers.
 

Warm Ischemia Worsens Partial Nephrectomy Outcomes, Study Finds

Jody A. Charnow July 20, 2010

Warm ischemia during partial nephrectomy (PN) on a solitary kidney is associated with an increased risk of acute renal failure (ARF) and CKD, according to researchers.
 

New Device May Facilitate Kidney Cancer Diagnosis

Jody A. Charnow June 14, 2010

Cook Medical, of Bloomington, Ind., has introduced BIGopsy Backloading Biopsy Forceps, a device that has a 4 mm3 biopsy cup to obtain large renal or ureteral tissue specimens for cancer diagnosis.
 

Kidney Stones

Stone Formers Found to Be at Higher Risk for MI

Jody A. Charnow August 19, 2010

Individuals who form kidney stones are at increased risk for myocardial infarction (MI) independent of CKD and other risk factors, according to researchers.
 

Socioeconomic Status Affects Stone Formers' Dietary Habits

Jody A. Charnow April 01, 2010

Socioeconomic status (SES) influences dietary habits, and this may strongly affect stone formation and recurrence, according to researchers at Emory University in Atlanta.
 

Doxazosin Effective for Clearing Ureteral Stones

Jody A. Charnow March 30, 2010

Doxazosin significantly improves expulsion of distal ureteral stones, according to researchers in Pakistan.
 

New Urocit K Formulation Introduced

Jody A. Charnow March 30, 2010

Mission Pharmacal Company has introduced the Urocit-K 15 mEq (potassium citrate) extended-release tablet.
 

Kidney Stone Disease Tied to Obesity

Jody A. Charnow February 16, 2010

During a five-year period, stones were diagnosed in 4.9% of obese and 2.6% of non-obese subjects.
 

Overactive Bladder

Potential Gene Biomarkers for OAB Identified

Rosemary Frei, MSc September 01, 2010

TORONTO—An analysis of gene-expression patterns in women with overactive bladder (OAB) may point the way to possible new biomarkers for the condition.
 

Overactive Bladder Linked to Inflammation

Jody A. Charnow May 29, 2010

SAN FRANCISCO—Increasing levels of C-reactive protein (CRP) are associated with increasing odds of overactive bladder (OAB), according to a population-based study of men and women.
 

PTNS Safe and Effective for Overactive Bladder

Jody A. Charnow April 01, 2010

Percutaneous tibial nerve stimulation (PTNS) is safe and effective for treating overactive bladder (OAB) symptoms, a recent study shows.
 

Study: Most OAB Cases Go Untreated

Jody A. Charnow February 05, 2010

The associated cost is a potential reason for undertreatment.
 

Study: Most Overactive Bladder Cases Go Untreated

Jody A. Charnow January 11, 2010

Only 24.4% of patients aged 45 years and older take drugs for the condition, according to researchers.
 

Premature Ejaculation

Novel Treatment for Premature Ejaculation Shows Promising Results

Jody A. Charnow June 01, 2010

SAN FRANCISCO—Pivotal clinical trials of a novel treatment for premature ejaculation (PE) have yielded promising results, a researcher announced here at a press conference during the American Urological Association annual meeting.
 

Topical Spray for PE Safe, Effective

John Schieszer August 19, 2009

Men suffering from premature ejaculation had a sixfold increase in intravaginal ejaculatory time.
 

Drug Works for Premature Ejaculation

Jody A. Charnow March 06, 2009

Dapoxetine shows efficacy in the treatment of premature ejaculation (PE), according to a new study that researchers say is the most comprehensive to date examining a pharmacologic treatment for PE.
 

Expert Panel Defines Premature Ejaculation

John Schieszer August 28, 2008

ORLANDO—For the first time, clinicians have an evidence-based definition of premature ejaculation (PE).
 

Premature Ejaculation Gets Evidence-Based Definition

Jody A. Charnow June 03, 2008

A panel of sexual health authorities has developed what they say is the first evidence-based definition of premature ejaculation (PE).
 

Prostate Cancer

ED Drugs Can Ease Post-Op Urinary Incontinence

Rosemary Frei, MSc September 07, 2010

TORONTO—Use of an oral phosphodiesterase type-5 inhibitor (PDE5i) significantly reduces urinary incontinence after radical prostatectomy (RP), according to data presented at the joint annual meeting of the International Continence Society and the International Urogynecological Association.
 

Ambiguities of the Prostate: Searching for Beacons in the Fog

Jeff Forster August 31, 2010

Twenty years ago, a man I revered calmly shared the news that he had just been diagnosed with metastatic prostate cancer. Frank A. Oski, MD, was chair of pediatrics at Johns Hopkins, a beloved, iconic, and iconoclastic figure to thousands of students, faculty, and practicing clinicians throughout the realm of children's health care, a brilliant mind who loved nothing better than tweaking the pretensions of the medically effete.
 

Surveillance a Suitable Option for Low-Risk PCa

Jody A. Charnow August 19, 2010

Active surveillance may be a suitable option for many men with low-risk prostate cancer (PCa), Swedish researchers concluded.
 

Post-RP Statins May Lower PSA Relapse Risk

John Schieszer August 19, 2010

SAN FRANCISCO—Initiating statin therapy after radical prostatectomy (RP) may decrease the risk of biochemical recurrence of prostate cancer, new data suggest.
 

PSA Testing Found to Reduce Prostate Cancer Mortality

Delicia Honen Yard August 19, 2010

Deaths from prostate cancer (PCa) fell by almost half after 14 years of biennial screening, according to data from a Swedish study.
 

Prostate Specific Antigen

PSA Testing Found to Reduce Prostate Cancer Mortality

Delicia Honen Yard August 19, 2010

Deaths from prostate cancer (PCa) fell by almost half after 14 years of biennial screening, according to data from a Swedish study.
 

PSA Rises More Slowly with Age in Diabetics

Jody A. Charnow June 03, 2010

SAN FRANCISCO—Men with diabetes experience significantly smaller increases in PSA level as they age compared with non-diabetics, according to findings reported here at the American Urological Association Annual Meeting.
 

PSA Doubling Time Predicts Survival After PSA Failure

Jody A. Charnow April 26, 2010

SAN FRANCISCO—PSA doubling time (PSADT) is the most important predictor of 15-year overall survival among men who experience biochemical recurrence after radical prostatectomy for prostate cancer, according to a study.
 

PSA Lower in Aspirin-Using Never Smokers

Jody A. Charnow April 01, 2010

Aspirin use is associated with lower PSA levels in men who have never smoked, data suggest.
 

PCA3 Beats PSA in Predicting Prostate Biopsy Outcomes

Jody A. Charnow March 05, 2010

SAN FRANCISCO—The prostate cancer gene 3 (PCA3) molecular urine test is more accurate than the PSA test in predicting outcomes of repeat biopsies, new findings confirm.
 

Reproductive Medicine

Anejaculation After RT Common

Jill Stein July 27, 2010

Most men who undergo radiation therapy (RT) for prostate cancer will develop anejaculation, a new study shows.
 

Testicular Cancer Treatments May Incur Risks

John Schieszer June 22, 2010

CHICAGO—Testicular cancer survivors treated with chemotherapy and radiotherapy are at increased risk for cardiovascular disease (CVD), researchers reported at the American Society of Clinical Oncology annual meeting. These patients also are at higher risk for hypertension and diabetes.
 

New Varicocele Technique Shows Promise

John Schieszer June 18, 2010

Recurrence rates after percutaneous embolization are similar to those of surgery, researcher says.
 

Alfuzosin Improves Ejaculatory Dysfunction

Jill Stein April 22, 2010

BARCELONA—Alfuzosin 10 mg once-daily (OD) improves ejaculatory dysfunction in sexually active men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH), according to new findings presented here at the 25th Anniversary European Association of Urology Congress.
 

High-Grade Prostate Cancer Linked to Male Infertility

Jody A. Charnow March 25, 2010

Infertile men may be at increased risk for high-grade prostate cancer (PCa), according to researchers at the University of California-San Francisco.
 

Urinary Incontinence

Modified TVT-O Technique Effective in Easing SUI

Rosemary Frei, MSc September 07, 2010

TORONTO—A modified inside-out transobturator (TVT-O) procedure is safe and effective for treating stress urinary incontinence (SUI) in women, according to data presented at the joint annual meeting of the International Continence Society and the International Urogynecological Association.
 

ED Drugs Can Ease Post-Op Urinary Incontinence

Rosemary Frei, MSc September 07, 2010

TORONTO—Use of an oral phosphodiesterase type-5 inhibitor (PDE5i) significantly reduces urinary incontinence after radical prostatectomy (RP), according to data presented at the joint annual meeting of the International Continence Society and the International Urogynecological Association.
 

Potential Gene Biomarkers for OAB Identified

Rosemary Frei, MSc September 01, 2010

TORONTO—An analysis of gene-expression patterns in women with overactive bladder (OAB) may point the way to possible new biomarkers for the condition.
 

Caesarean Births Lower Prolapse Risk

Rosemary Frei, MSc August 27, 2010

TORONTO—Caesarean deliveries significantly reduce the risk of prolapse compared with vaginal delivery, according to a data presented at the joint International Continence Society—International Urogynecological Association annual meeting - but only if women had all their deliveries by Caesarian. Having even one baby vaginally removed this effect.
 

Risk Factors For Male UI Identified

Jody A. Charnow July 12, 2010

SAN FRANCISCO—Researchers have identified medical conditions that are independently associated with moderate to severe urinary incontinence (UI) in men. These include major depression, hypertension, and prostatic enlargement.
 

Urinary Tract Infections

Renal Impairment Linked to E. coli Infection

Rosemary Frei, MSc July 12, 2010

MONTREAL—A decade after contracting acute diarrheal illness from infection with Escherichia coli 0157:H7, individuals are at increased risk for definite renal impairment with microalbuminuria, hypertension, and cardiovascular events compared with individuals not infected with the pathogen.
 

UTI Pathogens Differ in Renal Transplant Patients

Jody A. Charnow June 27, 2010

MUNICH, GERMANY—Urinary tract infections (UTIs) caused by non-coliform bacteria are significantly more common among renal transplant patients compared with the general population, according to a British study.
 

Intraurethral Catheters Recommended

May 01, 2010

They cause fewer UTIs than indwelling catheters in men at high risk during anesthesia and surgery.
 

Post-Op Infectious Complications Characterized

Jody A. Charnow March 02, 2010

The problems developed following 20% of major urologic procedures in patients with chronic bacteriuria.
 

Oral Drug Is An Appropriate Option for Resistant UTIs

John Schieszer November 19, 2009

In a study, only 3% of ESBL-producing Escherhicia coli isolates were resistant to fosfomycin.
 
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