Bladder Cancer

TERT Test May Improve Detection of Bladder Cancer Recurrence

TERT Test May Improve Detection of Bladder Cancer Recurrence

By

In a study, a positive test result was associated with a 5-fold increased risk of recurrent non-muscle invasive bladder cancer.

Robotic, Open Radical Cystectomy Offer Similar Results

Robotic, Open Radical Cystectomy Offer Similar Results

By

A new review shows no significant differences in oncologic outcomes, long-term complications, and health-related quality of life between robot-assisted and open radical cystectomy.

Advanced Cancer Patients Ask for Secondary Germline Results

Advanced Cancer Patients Ask for Secondary Germline Results

The researchers found that 57% of participants expressed interest in learning their secondary germline findings, while 29% and 14%, respectively, were equivocal or disinterested.

Symptomatic Bladder Cancer Recurrence Linked With Worse Survival

Symptomatic Bladder Cancer Recurrence Linked With Worse Survival

By

Symptomatic recurrence was associated with a nearly 2-fold higher risk of death from the time of recurrence versus surveillance-detected recurrence.

Surgery, Combined Modality Offer Similar MIBC Outcomes

Surgery, Combined Modality Offer Similar MIBC Outcomes

By

Meta-analysis reveals no significant difference in overall-, disease-specific, and progression-free survival between radical cystectomy and radiation-based, bladder preservation therapy.

MIBC Patients Should Be Followed Long-term After Cystectomy

MIBC Patients Should Be Followed Long-term After Cystectomy

After recurrent disease, 5-year overall survival was worse among patients with late recurrence.

Worse Survival After Robotic Cystectomy Seen at Low-Volume Centers

Worse Survival After Robotic Cystectomy Seen at Low-Volume Centers

By

The researchers found lower overall survival among patients undergoing robot-assisted radical cystectomy at hospitals performing 10 or fewer procedures during 2010 to 2012.

Keytruda Approved for All Cancers With Specific Genetic Biomarker

Keytruda Approved for All Cancers With Specific Genetic Biomarker

Of 149 individuals with such tumors who took Keytruda in clinical trials, nearly 40% had a complete or partial remission.

Renal, Bladder Cancer Linked to Physical Inactivity

Renal, Bladder Cancer Linked to Physical Inactivity

By

Renal and bladder cancer patients were, respectively, 77% and 73% more likely to report lifetime physical inactivity than controls without cancer.

Pure Bladder Cancer Variants Linked to Worse Survival After RC

Pure Bladder Cancer Variants Linked to Worse Survival After RC

By

Patients with a pure variant had significantly lower survival odds than those with pure urothelial carcinoma over a median 6.5 years of follow up.

E-Cigarettes And Increased Risk Of Bladder Cancer Linked

E-Cigarettes And Increased Risk Of Bladder Cancer Linked

Research suggests that both cigarettes and e-cigarettes are tied to an increased risk of bladder cancer.

Real-World mUCB Patient Survival Worse Than in Clinical Trials

Real-World mUCB Patient Survival Worse Than in Clinical Trials

By

Just 1 in 4 patients diagnosed with metastatic urothelial carcinoma of the bladder survive for a year, according to US national registry data.

Robot-assisted Radical Cystectomy on the Rise

Robot-assisted Radical Cystectomy on the Rise

By

By 2014 to 2015, 1 in 3 bladder cancer surgical procedures performed in the United States were robot-assisted.

Neoadjuvant Chemo Benefits Some Variant MIBC Patients

Neoadjuvant Chemo Benefits Some Variant MIBC Patients

By

Researchers find prolonged survival among patients with neuroendocrine muscle-invasive bladder cancer.

Post-chemo PD-L1 Tied to Worse Prognosis in Bladder Cancer Pts

Post-chemo PD-L1 Tied to Worse Prognosis in Bladder Cancer Pts

By

Five-year cancer-specific survival rates were 48.1% and 69.6% for PD-L1 positive and negative patients, respectively.

Bladder Cancer Survival Worse Among Women Despite RC

Bladder Cancer Survival Worse Among Women Despite RC

By

Among stage 2 to 4 bladder cancer patients, women had lower cancer-specific survival than men.

Variant Histology Predicts Worse Bladder Cancer Outcomes

Variant Histology Predicts Worse Bladder Cancer Outcomes

By

Study finds a higher death risk following radical cystectomy for squamous cell and small cell carcinoma and micropapillary histologic subtypes.

VTE Risk Continues Long After Bladder Cancer Surgery

VTE Risk Continues Long After Bladder Cancer Surgery

By

The cumulative incidence of venous thromboembolism following radical cystectomy was nearly 6.7% over 10 years.

Post-Cystectomy Deaths Among HD Patients Seldom Due to Cancer

Post-Cystectomy Deaths Among HD Patients Seldom Due to Cancer

By

Following radical cystectomy for bladder cancer, end-stage renal disease patients are 3-4 times more likely to die from causes other than cancer.

Continent Diversion After Bladder Cancer Surgery on the Decline

Continent Diversion After Bladder Cancer Surgery on the Decline

By

Use of continent diversion procedures peaked in 2008, and has been decreasing since.

Bladder Cancer Patient Smoking Intensity Influences Survival

Bladder Cancer Patient Smoking Intensity Influences Survival

By

Patients smoking 1 or more packs of cigarettes per day had a higher risk of death compared with those who smoked less than 1.

Blue Light Cystoscopy Increases Bladder Cancer Detection Rate

Blue Light Cystoscopy Increases Bladder Cancer Detection Rate

By

Sensitivity is 90% for BLC compared with 75% for white light cystoscopy.

Bladder Cancer Recurrence Risk Lower in Metformin Users

Bladder Cancer Recurrence Risk Lower in Metformin Users

By

The protective effect of the diabetes drug metformin among patients who undergo surgery for non-muscle invasive bladder cancer is dose dependent, according to a study.

Blacks More Likely to Die From Metastatic Bladder Cancer

Blacks More Likely to Die From Metastatic Bladder Cancer

By

In a study, 2-year survival rates were 14.4% for whites compared with 6.5% for blacks.

Radical Cystectomy for Muscle-invasive UCB Offers Better Survival

Radical Cystectomy for Muscle-invasive UCB Offers Better Survival

By

Radical cystectomy is associated with better long-term overall survival than trimodal therapy, new study shows.

Pembrolizumab As Second-Line Tx for Urothelial Cancer Ups Survival

Pembrolizumab As Second-Line Tx for Urothelial Cancer Ups Survival

By

Use of the monoclonal antibody was associated with a 27% lower risk of death versus chemotherapy.

Pre-Cystectomy Chemo Does Not Up Survival in 'Real World' Setting

Pre-Cystectomy Chemo Does Not Up Survival in 'Real World' Setting

By

Finding contrasts with results of randomized clinical trials.

Bladder Surgery Complications Predicted by New Model

Bladder Surgery Complications Predicted by New Model

By

Nomograms specific to radical cystectomy currently do not exist to aid stratification of a patient's risks for complications.

Adjuvant Radiation Therapy Common in MIBC

Adjuvant Radiation Therapy Common in MIBC

By

Survey finds that 46% of radiation oncologists have administered ART to patients with muscle-invasive bladder cancer on at least one occasion.

Post-Radical Cystectomy Survival Outcomes Predicted by Preop NLR

Post-Radical Cystectomy Survival Outcomes Predicted by Preop NLR

By

A neutrophil-to-lymphocyte ratio below 3.09 is associated with significantly longer overall and disease-specific survival.

Sign Up for Free e-newsletters