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Bladder Cancer

Spread of Bladder Cancer To Lungs Tied to a Protein

April 30, 2012

Versican—a protein involved in cancer cell migration—is a driver of lung metastasis in bladder cancer.
 

Adding Chemo to Radiotherapy for MIBC Improves Outcomes

April 25, 2012

Synchronous chemotherapy combined with radiotherapy significantly improves locoregional control of muscle-invasive bladder cancer (MIBC) compared with radiotherapy alone, according to British researchers.
 

Bladder Cancer Diagnosis Encourages Smokers to Quit

April 23, 2012

Most commonly cited reasons for quitting: bladder cancer diagnosis, advice of urologist
 

Neoadjuvant Chemotherapy Urged for Rare Type of Bladder Cancer

April 20, 2012

Neoadjuvant chemotherapy for patients with small cell urothelial carcinoma (SCUC) improves their likelihood of survival compared with a historical cohort of patients treated with initial cystectomy, a study found.
 

Prolonged Hospital Stays After Cystectomy Decreasing

March 30, 2012

The likelihood of a prolonged hospital stay following radical cystectomy in the United States has decreased in the past decade, a study found.
 

Female Gender, Low BMI Raise Bladder Perforation Risk

March 23, 2012

Female gender and low body mass index (BMI) are risk factors for inadvertent bladder performation during transurethral resection of bladder tumors, German researchers reported online ahead of print in the Journal of Urology.
 

Bladder Cancer Death Risk May No Longer Be Higher in Women

February 27, 2012

PARIS—Previous research has shown that cancer-specific survival (CSS) after radical cystectomy for bladder cancer is significantly worse for women than men, but new data presented at the 27th Annual Congress of the European Association of Urology suggest that this may no longer be the case.
 

Prophylactic Antibiotics Unnecessary for Outpatient Cystoscopy

February 25, 2012

PARIS—Antibiotic prophylaxis and risk-based stratification are unnecessary for most patients undergoing outpatient flexible cystoscopy, researchers reported at the 27th Annual Congress of the European Association of Urology.
 

Study: Form of Bladder Cancer Increased by 56%

February 22, 2012

Although a detailed trend analysis of 127,614 U.S. cases of first primary bladder cancer demonstrated a 9% overall drop in disease occurrence between 1973 and 2007, papillary transitional cell carcinoma (PTCC)—one of two main subtypes—increased by 56% over that period.
 

Active Surveillance An Option for Bladder Cancer

February 16, 2012

LONDON—Low-risk non-muscle invasive bladder cancer (NMIBC) could be safely managed by periods of active surveillance rather than aggressive resection surgery and frequent cystoscopic follow up.
 

Circulating Tumor Cells Predict Worse Outcomes in Bladder Cancer Patients

February 04, 2012

SAN FRANCISCO—The presence of circulating tumor cells (CTC) in the peripheral blood of patients with urothelial carcinoma of the bladder (UCB) prior to radical cystecomy are associated with worse disease outcomes, researchers reported here at the annual Genitourinary Cancers Symposium.
 

Similar Outcomes Found with Open, Robotic Cystectomy

February 04, 2012

SAN FRANCISCO—Researchers who compared open and robotic cystectomy for bladder cancer found no significant difference in key outcomes after a median three years of follow-up, according to study findings presented here at the annual Genitourinary Cancers Symposium.
 

Comorbid Illnesses Worsen Post-Cystectomy Outcomes

February 01, 2012

Greater comorbid illness increases the likelihood of complications after radical cystectomy for bladder cancer among patients older than 70 years, according to German researchers.
 

Smaller Bladder Tumors Less Like to Recur After Surgery

December 10, 2011

Non-muscle-invasive bladder tumors 15 mm or less in diameter are associated with a lower risk of recurrence after surgical treatment compared with larger tumors, according to researchers.
 

Extended LND Improves Outcomes in Selected Bladder Cancer Patients

November 28, 2011

Extended lymph node dissection (LND) does not significantly change overall disease recurrence and survival patterns in patients who undergo radical cystectomy for bladder cancer compared with limited LND, but certain patient subgroups experience improvements in these outcomes, a study found.
 

Diabetes Increases Bladder Ca Recurrence, Progression Risk

November 21, 2011

Diabetes mellitus (DM) appears to be an independent predictor of disease recurrence and progression among patients with non-muscle invasive bladder cancer (NMIBC), according to investigators.
 

Neutrophil/Lymphocyte Ratio Can Upstage Bladder Cancer Patients Prior to Surgery

November 04, 2011

SAN FRANCISCO—Prior to radical cystectomy for bladder cancer, preoperative neutrophil/lymphocyte ratio (NLR) can identify patients at risk for having non-organ-confined disease and who may benefit from neoadjuvant chemotherapy, University of Wisconsin investigators reported at the American College of Surgeons 97th Clinical Congress.
 

Cancer Risk Higher in Transplant Recipients

November 02, 2011

Infection-related and unrelated cancers develop more frequently in solid organ transplant recipients than in the general population, according to researchers.
 

Bladder Cancer Survival Lowest in Blacks

November 01, 2011

Among patients with the malignancy, blacks are 29% more likely to die than whites, a study found.
 

Cystoscopy Alone is the Most Cost-Effective Way to Detect Bladder Cancer Recurrence

October 26, 2011

Cystoscopy without the aid of urinary markers is the most cost-effective strategy for detecting recurrence of non-invasive bladder cancer, according to researchers.
 

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Commentary


Dr. Uzzo

The merits of PSA screening have been widely debated due largely to its low specificity for prostate cancer (PCa), especially for high-grade disease.

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