PAE Safe, Effective in BPH Patients with Medium and Large Prostates
Outcomes were significantly better in men with large prostates, however.
Prostatic arterial embolization (PAE) is safe and effective for treating benign prostatic hyperplasia (BPH) in men with medium and large prostates, according to the findings of a Chinese study published online in BJU International.
The study, by Maoqiang Wang, MD, and colleagues, included 115 men with a mean age of 71.5 years diagnosed with lower urinary tract symptoms due to BPH refractory to medical treatment. Researchers divided the patients into 2 groups: Group A included patients with large prostates (mean volume of 129 mL) and group B included patients with a medium-size prostate (mean volume of 64 mL).
Results showed no significant difference in technical success rate between groups A and B (93.8% and 96.8%). Of the 115 men, 101 (55 in group A and 46 in group B) completed follow-up (mean 17 months). After PAE, both groups experienced significant improvements from baseline in International Prostate Symptom Score (IPSS), quality of life (QoL), post-void residual (PVR), prostate volume (PV), and maximum flow rate (Qmax). Outcomes in group A were significantly better with respect to IPSS, Qmax, PVR, PV, and QoL compared with group B.