AUA 2016

Smaller Renal Tumors Predict Longer Surgical Wait Times

Smaller Renal Tumors Predict Longer Surgical Wait Times

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Patients whose surgical wait time was 3 months or more versus less than 3 months had 10-fold increased odds of having a smaller tumor.

Deceased-Donor Age Affects Kidney Transplant Outcomes

Deceased-Donor Age Affects Kidney Transplant Outcomes

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Recipients of kidneys from individuals who donated the organs after cardiac death are more likely to experience graft loss and delayed graft function.

Metformin May Have a Protective Effect in Bladder Cancer Patients

Metformin May Have a Protective Effect in Bladder Cancer Patients

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Diabetics taking the drug had a significant 68% decreased risk of grade progression compared with diabetics not on the drug.

Hypercalciuria Linked to High Urinary Sodium

Hypercalciuria Linked to High Urinary Sodium

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Decreasing salt intake could decrease the risk of recurrent kidney stones.

New Study Supports Use of Trimodal Therapy for MIBC

New Study Supports Use of Trimodal Therapy for MIBC

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Researchers find no difference in 5-year disease-specific survival between multi-disciplinary bladder-sparing approach and radical cystectomy.

Smokers Face Delayed Continence Recovery After Prostate Surgery

Smokers Face Delayed Continence Recovery After Prostate Surgery

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Large prostates and bladder neck sparing also predict longer time to return of continence.

Testosterone Replacement Safe for Men With Prostate Cancer

Testosterone Replacement Safe for Men With Prostate Cancer

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Findings emerge from a study of hypogonadal men who underwent radiation therapy, surgery, or active surveillance for prostate cancer.

Cardiac Event Risk in PCa Patients Higher After Radiation Than Surgery

Cardiac Event Risk in PCa Patients Higher After Radiation Than Surgery

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Radiation therapy also is associated with a greater likelihood of fractures.

Adjuvant Docetaxel Does Not Help Biochemical DFS in High-risk PCa

Adjuvant Docetaxel Does Not Help Biochemical DFS in High-risk PCa

In prostate cancer, adjuvant docetaxel without hormone therapy did not improve biochemical disease-free survival after radical prostatectomy.

TRUS-biopsy Inferior for Prostate Cancer Detection

TRUS-biopsy Inferior for Prostate Cancer Detection

Transrectal ultrasound-guided (TRUS) prostate biopsy poorly detects and rules out clinically significant prostate cancer.

Enzalutamide-Abiraterone-Leuprolide Ineffective for Localized PCa

Enzalutamide-Abiraterone-Leuprolide Ineffective for Localized PCa

Adding enzalutamide to abiraterone acetate and leuprolide acetate does not appear to be effective for the treatment of localized high-risk prostate cancer.

Cytoreductive RC Aids Survival of Metastatic Bladder Cancer Patients

Cytoreductive RC Aids Survival of Metastatic Bladder Cancer Patients

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Patients who underwent debulking had significantly longer overall survival compared with those who did not (median 15.7 vs 10 months).

Patients on Psychiatric Meds Report More Severe OAB Symptoms

Patients on Psychiatric Meds Report More Severe OAB Symptoms

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These same patients, however, had less intense detrusor overactivity, urodynamic evaluation revealed.

Survival Advantage Confirmed for Nephrectomy in mRCC

Survival Advantage Confirmed for Nephrectomy in mRCC

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About 25% of patients who present with metastatic renal cancer will undergo nephrectomy after diagnosis.

Bariatric Surgery May Ease LUTS in Obese Men

Bariatric Surgery May Ease LUTS in Obese Men

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Study documents significant improvements in frequency, urgency, and nocturia.

Cytoreductive Nephrectomy Benefits Select mRCC Patients Taking TT

Cytoreductive Nephrectomy Benefits Select mRCC Patients Taking TT

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Among patients treated with targeted therapy, overall survival was 17.1 months for CN recipients vs 7.7 months for those without CN.

Neoadjuvant Chemo Rarely Used in Upper Tract Urothelial Cancer

Neoadjuvant Chemo Rarely Used in Upper Tract Urothelial Cancer

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Therapy used in less than 5% of cases, even in those with higher clinical stage.

PPIs Linked With Higher Rate of Post-RP Complications

PPIs Linked With Higher Rate of Post-RP Complications

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Prostate cancer patients taking proton pump inhibitors also had pathologically higher stage disease.

HoLEP Improvements in BPH Symptoms Durable Out to 10 Years

HoLEP Improvements in BPH Symptoms Durable Out to 10 Years

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Patients experienced a sustained decrease in AUA Symptom Score, and 95% of patients report being satisfied or very satisfied with the procedure.

Baseline PSA at Age 55-60 Predicts Prostate Cancer Risk

Baseline PSA at Age 55-60 Predicts Prostate Cancer Risk

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The higher the baseline PSA levels, the greater the risk of being diagnosed with any or significant prostate cancer.

Renal Transplant Patients At Higher Risk of Papillary RCC

Renal Transplant Patients At Higher Risk of Papillary RCC

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Only this histologic variant occurs at a significantly higher incidence in renal allograft recipients than the non-transplant population.

Novel Oral Testosterone Shows Long-Term Safety, Tolerability

Novel Oral Testosterone Shows Long-Term Safety, Tolerability

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In particular, no hepatic toxicities emerged during a 52-week phase 3 trial.

Salvage Radical Prostatectomy Offers Good Long-Term Outcomes

Salvage Radical Prostatectomy Offers Good Long-Term Outcomes

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Minimally invasive surgery is associated with a lower incidence of bladder neck contracture.

Long-Term RP Outcomes Better for cT1a Prostate Cancer

Long-Term RP Outcomes Better for cT1a Prostate Cancer

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Study documents superior recurrence- and metastasis-free survival compared with cT1b tumors.

Bladder Preservation Therapy for MIBC Predicts Worse Survival

Bladder Preservation Therapy for MIBC Predicts Worse Survival

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Mortality risk decreases with increasingly stringent BPT compared with radical cystectomy.

Mortality Rate Higher Among Bodybuilders

Mortality Rate Higher Among Bodybuilders

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Reasons are unclear, but use of testosterone and other performance enhance drugs could be a contributing factor.

Higher Radiation Dose Key to Better Brachytherapy Outcomes

Higher Radiation Dose Key to Better Brachytherapy Outcomes

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A biologic effective dose less than 170 Gy2 is associated with a 2-fold increase risk dying from prostate cancer versus higher doses.

Erectile Function Recovery Better With Delayed Radiotherapy After RP

Erectile Function Recovery Better With Delayed Radiotherapy After RP

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The chances of erectile function recovery improved when patients received radiation treatment more than 16 months after surgery.

More mRCC Patients Receiving Treatment

More mRCC Patients Receiving Treatment

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Cytoreductive nephrectomy (CN) use remained stable in the targeted therapy era, but more patients are receiving a combination of CN and systemic therapy.

Dutasteride Cuts Risk of Prostate Biopsy-Related UTIs

Dutasteride Cuts Risk of Prostate Biopsy-Related UTIs

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In a study, use of the medication was associated with a significant 61% decreased risk.

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