VTE Risk Factors in Radical Cystectomy Patients Identified

VTE is more likely in patients with neurologic comorbidities and increased operative time.
VTE is more likely in patients with neurologic comorbidities and increased operative time.

ORLANDO—Bladder cancer patients treated with radical cystectomy are at high risk for venous thromboembolism (VTE), according to a study presented at the American Urological Association 2014 annual meeting. The risk is higher among patients with neurologic comorbidities and longer operative time.

Using the American College of Surgeons-National Surgical Quality Improvement Program database, Josip Vukina, MD, MPH, and colleagues at the University of North Carolina in Chapel Hill studied patients undergoing radical cystectomy from 2005-2011.

Of 878 patients who had undergone radical cystectomy, 50 had experienced VTE, most of which were deep venous thrombosis (50%) followed by pulmonary embolism (26%) or both (24%).

Patients with 1 or more neurologic comorbidities had a significant 2.7 times increased risk of VTE. Each additional 60 minutes of operative time was associated with a significant 19% increased risk of VTE.

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