Pyuria, Microhematuria Duration After Prostate Surgery Quantified

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ATLANTA—Pyuria persists longer than microhematuria after prostatic surgery and it is significantly associated with resected prostate weight, according to a study presented at the American Urological Association 2012 annual meeting.

The investigators noted that abnormal findings in urinalysis could lead to unnecessary diagnostic approaches after treatment. Based on their study findings, they concluded: “Pyuria and microhematuria after prostate surgery are not always significant clinical findings,” the researchers concluded in a poster presentation.

The study, by Daniel Olvera-Posada, MD, of Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán in Mexico City, and colleagues, included 85 men having prostate surgery (either for benign prostatic enlargement or urinary retention associated with prostate cancer). Of the 85 patients, 44 underwent monopolar transurethral resection of the prostate (TURP), 27 underwent bipolar TURP, and 14 underwent open prostatectomy.

The researchers found that pyuria and microhematuria persisted for a median of 274 and 176 days, respectively. The difference in the time for these problems to resolve was statistically significant.

In a subgroup analysis, use of monopolar versus bipolar TURP and previous treatment with 5-alpha reductase inhibitors did not significantly affect median time to normalization.

Dr. Olvera-Posada's group observed a significant correlation between resected prostate weight and a longer duration of pyuria after endoscopic surgery. Resection of more than 23 grams significantly prolongs the median number of days to resolution of pyuria.

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