Anesthetic Spray May Work For Premature Ejaculation

Share this article:
BJU Int. 2007;99:369-375
 
An aerosol anesthetic spray may be a safe and effective treatment for premature ejaculation (PE), British researchers report.
 
Michael Wyllie, MD, of Urodoc Ltd., and his colleagues studied 54 men, randomly assigning 26 to receive TEMPE (topical eutectic mixture for PE) and 28 to receive placebo. TEMPE contains lidocaine and prilocaine. Active drug and placebo were presented in metered-dose aerosol spray devices that were identical in appearance. The men sprayed their glans penis three times during the 15 minutes before intercourse.
 
Complete efficacy data were available for 20 men in the TEMPE arm and 23 in the placebo arm. TEMPE resulted in a mean intravaginal ejaculatory latency time (IELT) of 4.9 minutes compared with 1.6 minutes in the placebo group, which was a statistically significant increase. Additionally, 83% of men found the spray easy to use. Mild-to-moderate numbness occurred in three subjects (12%), but did not lead to discontinuation.
 
“The study results suggest that TEMPE might be useful as a first-line treatment for men with PE,” the authors wrote.
 
The study recruited men with PE based on Diagnostic and Statistical Manual-IV (DSM-IV) criteria, and did not require specific IELT thresholds for inclusion. “As such, it is likely that the population studied here is representative of the general population with PE.”
Share this article:
You must be a registered member of RUN to post a comment.
close

Next Article in World Literature Review

Sign Up for Free e-newsletters