Anemia

Iron-based Binder Improves Phosphorus Levels in Dialysis Patients

Iron-based Binder Improves Phosphorus Levels in Dialysis Patients

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The proportion of patients with serum phosphorus levels within target range rose from 22% to 65% within 6 months of starting ferric citrate treatment.

Ferritin Spike Soon After Hemodialysis Initiation Ups Mortality Risk

Ferritin Spike Soon After Hemodialysis Initiation Ups Mortality Risk

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Up to a 49% higher risk of death observed in patients who had a 400 ng/mL increase in serum ferritin from baseline values compared with patients who had relatively stable ferritin levels.

Optimal Iron Status for Hemodialysis Patients Reported

Optimal Iron Status for Hemodialysis Patients Reported

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Japanese researchers conclude that a serum ferritin level below 90 ng/mL and TSAT of 20% or higher was optimal for achieving a hemoglobin level of 10 g/dL or higher.

Low Hemoglobin, Low SEVR Linked in Chronic Kidney Disease

Low Hemoglobin, Low SEVR Linked in Chronic Kidney Disease

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Researchers used pulse wave analysis to measure subendocardial viability ratio, a measure of myocardial perfusion, and its association with hemoglobin.

RBC Distribution Width, Dialysis Patient Mortality Linked

RBC Distribution Width, Dialysis Patient Mortality Linked

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As red blood cell distribution width increases, so does the risk of death from any cause.

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

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Anemic patients were 41% and 80% more likely to have coronary artery disease and peripheral artery disease than non-anemic patients.

New Review Highlights Iron Deficiency Anemia in CKD

New Review Highlights Iron Deficiency Anemia in CKD

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Intravenous iron should be strongly considered for patients treated with ESAs or hemodialysis, according to reviewers.

Low Testosterone Tied to Anemia Risk in Men With Type 2 Diabetes

Low Testosterone Tied to Anemia Risk in Men With Type 2 Diabetes

In type 2 diabetic male patients, a low testosterone level was found to be associated with anemia. These findings are consistent with previous reports.

Ferric Citrate Modestly Improves Anemia, Study Confirms

Ferric Citrate Modestly Improves Anemia, Study Confirms

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Significantly more patients treated with ferric citrate increased their hemoglobin levels by 1 g/dL or more over 8 weeks.

Anemia Burden in Chronic Kidney Disease Described

Anemia Burden in Chronic Kidney Disease Described

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The prevalence of low hemoglobin levels increases with declining renal function.

Triferic Pharmacokinetics Characterized

Triferic Pharmacokinetics Characterized

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Ferric pyrophosphate citrate delivered via dialysate or intravenously rapidly donates iron to transferrin and is rapidly cleared from the circulation.

Anemia Indication Sought for Phosphate Binder

Anemia Indication Sought for Phosphate Binder

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Company asks FDA to approve ferric citrate for iron deficiency anemia in patients with non-dialysis dependent chronic kidney disease.

How 'Bundling' Changed Dialysis Care

How 'Bundling' Changed Dialysis Care

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Decreased use of erythropoiesis-stimulating agents and an uptick in peritoneal dialysis use are among the trends.

Anemia, Bone Density Improve With Testosterone Replacement

Anemia, Bone Density Improve With Testosterone Replacement

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Older men on TRT versus placebo for 1 year had improved hemoglobin levels and volumetric bone mineral density and estimated bone strength.

Red Blood Cell Size Linked With Mortality in CKD Patients

Red Blood Cell Size Linked With Mortality in CKD Patients

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CKD patients with larger erythrocyte volumes had more than triple the risk of dying from cardiovascular causes, researchers reported.

Anemia Control Similar for Transplant Patients Re-entering Dialysis

Anemia Control Similar for Transplant Patients Re-entering Dialysis

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Investigators observed no difference in hemoglobin level between transplant recipients and non-transplant CKD patients starting hemodialysis.

Female PD Patients Have Lower Hemoglobin Despite Anemia Treatment

Female PD Patients Have Lower Hemoglobin Despite Anemia Treatment

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New and established peritoneal dialysis patients both showed this trend.

Iron-Based Phosphate Binder Safely Treats Anemia in CKD Patients

Iron-Based Phosphate Binder Safely Treats Anemia in CKD Patients

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In a study 52.1% of patients receiving ferric citrate attained a 1.0 g/dL or greater increase in hemoglobin compared with just 19.1% receiving placebo.

IV Iron Formulations Associated With Similar Mortality

IV Iron Formulations Associated With Similar Mortality

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New study finds no difference in all-cause and cause-specific mortality between iron sucrose and sodium ferric gluconate complex.

Shift in Anemia Management in CKD Patients Identified

Shift in Anemia Management in CKD Patients Identified

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Use of ESAs declined while use of blood transfusions increased between 2008 and 2012.

Artificial Red Blood Cell Created

Artificial Red Blood Cell Created

The surface chemistry of the polymer reacts to the pH level of blood as it travels through the body.

Anemia in Non-Dialysis-Dependent CKD Patients Characterized

Anemia in Non-Dialysis-Dependent CKD Patients Characterized

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The condition is present in more than half of Medicare patients with stage 3-5 chronic kidney disease.

Anemia Management During Early HD Varies By Country

Anemia Management During Early HD Varies By Country

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US patients receive higher intravenous iron and ESA doses during the first year of hemodialysis compared with those in Europe.

Anemia Linked to Vitamin D Insufficiency in Children With CKD

Anemia Linked to Vitamin D Insufficiency in Children With CKD

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Low vitamin D status was associated with a 2-fold higher risk for anemia.

Longer Red Blood Cell Storage Does Not Up Death After Transfusion

Longer Red Blood Cell Storage Does Not Up Death After Transfusion

Results were homogeneous, with differences in absolute mortality consistently less than 1% among the most extreme exposure categories.

Optimal Vitamin C Dose for Anemia in Hemodialysis Patients Unclear

Optimal Vitamin C Dose for Anemia in Hemodialysis Patients Unclear

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Pending future research, patients should avoid taking more than 120 mg per day.

Cinacalcet Possibly Improves Anemia

Cinacalcet Possibly Improves Anemia

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SHPT patients who received 6 months of cinacalcet treatment had a 10% increase in the odds of reaching target hemoglobin levels.

Dialysis Patient Outcomes Not Worse After Bundling, ESA Label Changes

Dialysis Patient Outcomes Not Worse After Bundling, ESA Label Changes

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Study finds no increased risk of major adverse cardiovascular events and death.

Factors Linked to Worse Post-Surgical Kidney Function ID'd

Factors Linked to Worse Post-Surgical Kidney Function ID'd

Factors including low preoperative mean arterial BP tied to increases in eGFR, kidney injury.

Lower ESA Use for Anemia Linked to Maintenance IV Iron

Lower ESA Use for Anemia Linked to Maintenance IV Iron

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Management strategy also is associated with reduced mortality risk, but not achievement of hemoglobin targets.

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