Anemia

ESRD Anemia Responds to Investigational Oral Drug

ESRD Anemia Responds to Investigational Oral Drug

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In a phase 2 trial, roxadustat maintained hemoglobin levels over 19 weeks as well as epoetin alfa.

IV Iron Safe for Treating Anemia in Acute Kidney Injury Patients

IV Iron Safe for Treating Anemia in Acute Kidney Injury Patients

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In a case-control study, the treatment did not adversely affect mortality or recovery from AKI.

Earlier ESA Initiation May Improve Renal Outcomes

Earlier ESA Initiation May Improve Renal Outcomes

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Study shows benefit of initiating epoetin beta therapy at hemoglobin levels not less than 10 g/dL in non-dialysis CKD patients.

Recombinant Erythropoietin Benefits Non-Dialysis CKD Patients

Recombinant Erythropoietin Benefits Non-Dialysis CKD Patients

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Treatment corrects anemia and improves quality of life, according to a systemic review.

Ergocalciferol Supplements Improve Vitamin D Deficiency, Not Anemia

Ergocalciferol Supplements Improve Vitamin D Deficiency, Not Anemia

Six-months of supplementation has no impact on epoetin utilization in HD patients with low 25(OH)D.

Hemoglobin Levels May Discriminate CKD Stages in the Elderly

Hemoglobin Levels May Discriminate CKD Stages in the Elderly

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In a study, investigators observed that levels were higher in those with stage 3a than stage 3b chronic kidney disease.

Weekly ESA Dosing at Dialysis Centers May Offer Time Savings

Weekly ESA Dosing at Dialysis Centers May Offer Time Savings

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The estimated potential staff time savings totaled 23 hours for an average facility with 70 patients, researchers found.

Ferumoxytol Similar in Safety to Other IV Iron Products

Ferumoxytol Similar in Safety to Other IV Iron Products

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Rates of death and important non-fatal outcomes between ferumoxytol and iron sucrose or sodium ferric gluconate do not differ significantly.

Transfusion, Mortality Link Varies With Hemoglobin, Heart Disease

Transfusion, Mortality Link Varies With Hemoglobin, Heart Disease

For ICU patients, hemoglobin level thresholds vary with presence of comorbid heart disease.

Anaphylaxis Risk Among IV Iron Products Ranked

Anaphylaxis Risk Among IV Iron Products Ranked

Risk of anaphylaxis associated with IV iron highest for iron dextran, lowest for iron sucrose.

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

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Having hemoglobin 9-11 g/dL prior to dialysis provided the best life expectancy.

Red Cell Distribution Width Linked With Mortality in Dialysis

Red Cell Distribution Width Linked With Mortality in Dialysis

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It is unclear whether RDW is a risk factor for early death or a byproduct of biological and metabolic imbalances.

Statins May Improve Response to Erythropoiesis-Stimulating Agents

Statins May Improve Response to Erythropoiesis-Stimulating Agents

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Patients prescribed the lipid-lowering agents were less likely to exhibit hyporesponsiveness to the medications.

Erythropoietin Resistance More Likely in Female Dialysis Patients

Erythropoietin Resistance More Likely in Female Dialysis Patients

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Study finds no gender differences in parathyroid hormone, ferritin, Kt/V, or age.

Vitamin C Found to Decrease Erythropoietin Requirement

Vitamin C Found to Decrease Erythropoietin Requirement

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In a study, the mean hemoglobin level increased significantly in hemodialysis patients with functional iron deficiency.

Iron Deficiency Ups Mortality in Renal Transplant Recipients

Iron Deficiency Ups Mortality in Renal Transplant Recipients

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The association is independent of anemia, according to researchers.

Anemia More Severe in Hemodialysis Patients with PEW

Anemia More Severe in Hemodialysis Patients with PEW

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Patients with vs. without protein-energy wasting syndrome had a significantly lower mean hemoglobin level.

HCV Ups Anemia-Related Event Risks in Hemodialysis Patients

HCV Ups Anemia-Related Event Risks in Hemodialysis Patients

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Hepatitis C viral infection found to increase likelihood of requiring blood transfusions and hemoglobin levels dropping below 8.5 g/dL.

Iron Deficiency Linked With Elevated FGF-23 in Pediatric CKD

Iron Deficiency Linked With Elevated FGF-23 in Pediatric CKD

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Iron deficiency may contribute to the relationship between proteinuria and excess FGF-23, researchers suggested.

Anemia Increases Cardiovascular Event Risk in PCI Patients with CKD

Anemia Increases Cardiovascular Event Risk in PCI Patients with CKD

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The odds of major adverse cardiac events were 46% to 76% higher in anemic vs. non-anemic patients.

TSAT May Better Predict ESA Response

TSAT May Better Predict ESA Response

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Unlike serum ferritin, transferrin saturation demonstrated an ability to predict the need for intravenous iron and ESA.

Darbepoetin Raises Stroke Risk in Diabetic CKD Patients

Darbepoetin Raises Stroke Risk in Diabetic CKD Patients

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RED-HF study confirms the increased stroke risk observed in TREAT.

Long-Acting ESAs May Improve Anemia, Prevent LVH

Long-Acting ESAs May Improve Anemia, Prevent LVH

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Successfully treating anemia in pre-dialysis CKD patients appears to prevent left ventricular remodeling.

Albuminuria May be a Risk Factor for Anemia in CKD

Albuminuria May be a Risk Factor for Anemia in CKD

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Kidney disease patients with macroalbuminuria were 86% more likely to be anemic.

Adverse Events in CKD Patients More Frequent with IV Iron

Adverse Events in CKD Patients More Frequent with IV Iron

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Trial stopped early due to a higher risk of serious cardiovascular events and infections with IV iron versus oral iron.

Iron Supplementation May Offer Survival Benefit in Advanced CKD

Iron Supplementation May Offer Survival Benefit in Advanced CKD

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It was associated with a 15% reduced risk of early death among pre-dialysis, stage 5 chronic kidney patients treated with ESAs.

Subcutaneous Erythropoietin Safer for Hemodialysis Patients

Subcutaneous Erythropoietin Safer for Hemodialysis Patients

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It reduces dose requirements and lowers the risk of death and hospitalization for cardiovascular complications compared with IV administration.

Higher Phosphorus Ups Anemia Risk

Higher Phosphorus Ups Anemia Risk

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Researchers find link in the non-dialysis population.

Risk Factors for CKD Progression ID'd

Risk Factors for CKD Progression ID'd

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Proteinuria, hyperphosphatemia, anemia linked more rapid annual decline in eGFR.

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