Anemia

Anemia, Bone Density Improve With Testosterone Replacement

Anemia, Bone Density Improve With Testosterone Replacement

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Older men on TRT versus placebo for 1 year had improved hemoglobin levels and volumetric bone mineral density and estimated bone strength.

Red Blood Cell Size Linked With Mortality in CKD Patients

Red Blood Cell Size Linked With Mortality in CKD Patients

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CKD patients with larger erythrocyte volumes had more than triple the risk of dying from cardiovascular causes, researchers reported.

Anemia Control Similar for Transplant Patients Re-entering Dialysis

Anemia Control Similar for Transplant Patients Re-entering Dialysis

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Investigators observed no difference in hemoglobin level between transplant recipients and non-transplant CKD patients starting hemodialysis.

Female PD Patients Have Lower Hemoglobin Despite Anemia Treatment

Female PD Patients Have Lower Hemoglobin Despite Anemia Treatment

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New and established peritoneal dialysis patients both showed this trend.

Iron-Based Phosphate Binder Safely Treats Anemia in CKD Patients

Iron-Based Phosphate Binder Safely Treats Anemia in CKD Patients

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In a study 52.1% of patients receiving ferric citrate attained a 1.0 g/dL or greater increase in hemoglobin compared with just 19.1% receiving placebo.

IV Iron Formulations Associated With Similar Mortality

IV Iron Formulations Associated With Similar Mortality

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New study finds no difference in all-cause and cause-specific mortality between iron sucrose and sodium ferric gluconate complex.

Shift in Anemia Management in CKD Patients Identified

Shift in Anemia Management in CKD Patients Identified

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Use of ESAs declined while use of blood transfusions increased between 2008 and 2012.

Artificial Red Blood Cell Created

Artificial Red Blood Cell Created

The surface chemistry of the polymer reacts to the pH level of blood as it travels through the body.

Anemia in Non-Dialysis-Dependent CKD Patients Characterized

Anemia in Non-Dialysis-Dependent CKD Patients Characterized

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The condition is present in more than half of Medicare patients with stage 3-5 chronic kidney disease.

Anemia Management During Early HD Varies By Country

Anemia Management During Early HD Varies By Country

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US patients receive higher intravenous iron and ESA doses during the first year of hemodialysis compared with those in Europe.

Anemia Linked to Vitamin D Insufficiency in Children With CKD

Anemia Linked to Vitamin D Insufficiency in Children With CKD

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Low vitamin D status was associated with a 2-fold higher risk for anemia.

Longer Red Blood Cell Storage Does Not Up Death After Transfusion

Longer Red Blood Cell Storage Does Not Up Death After Transfusion

Results were homogeneous, with differences in absolute mortality consistently less than 1% among the most extreme exposure categories.

Optimal Vitamin C Dose for Anemia in Hemodialysis Patients Unclear

Optimal Vitamin C Dose for Anemia in Hemodialysis Patients Unclear

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Pending future research, patients should avoid taking more than 120 mg per day.

Cinacalcet Possibly Improves Anemia

Cinacalcet Possibly Improves Anemia

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SHPT patients who received 6 months of cinacalcet treatment had a 10% increase in the odds of reaching target hemoglobin levels.

Dialysis Patient Outcomes Not Worse After Bundling, ESA Label Changes

Dialysis Patient Outcomes Not Worse After Bundling, ESA Label Changes

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Study finds no increased risk of major adverse cardiovascular events and death.

Factors Linked to Worse Post-Surgical Kidney Function ID'd

Factors Linked to Worse Post-Surgical Kidney Function ID'd

Factors including low preoperative mean arterial BP tied to increases in eGFR, kidney injury.

Lower ESA Use for Anemia Linked to Maintenance IV Iron

Lower ESA Use for Anemia Linked to Maintenance IV Iron

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Management strategy also is associated with reduced mortality risk, but not achievement of hemoglobin targets.

High CRP Ups Kidney Failure Risk in Diabetic CKD Patients With Anemia

High CRP Ups Kidney Failure Risk in Diabetic CKD Patients With Anemia

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End-stage renal disease is 32% more likely to develop in patients with C-reactive protein levels of 6.9 mg/L or higher vs 3.0 mg/L or lower.

Hypogonadism in Male HD Patients Linked to Poor ESA Response

Hypogonadism in Male HD Patients Linked to Poor ESA Response

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Other risk factors include reduced muscle mass and lower levels of physical activity.

Hemodialysis Patient Hyporesponsiveness to ESAs Ups Death Risk

Hemodialysis Patient Hyporesponsiveness to ESAs Ups Death Risk

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A recent study resulted in a new definition of less-than-optimal response to erythropoiesis-stimulating agents.

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

Most Cost-Effective Hb Target in Anemic CKD Patients Identified

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A hemoglobin level of 10.5 g/dL offers the optimal balance of cost and quality adjusted life years, researchers conclude.

Diabetes May Increase Anemia Risk in CKD Patients

Diabetes May Increase Anemia Risk in CKD Patients

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The odds of developing anemia were 2-fold greater among patients with than without diabetes mellitus.

Anemic CKD Patients Have Lower Health-Related Quality of Life

Anemic CKD Patients Have Lower Health-Related Quality of Life

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Anemia was associated with impaired activity levels at CKD stages 3, 4, and dialysis.

ESA Resistance Linked to Vitamin B6 Treatment

ESA Resistance Linked to Vitamin B6 Treatment

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IV administration of vitamin B6 did not improve anemia or abnormal bone metabolism over 6 months.

High-Dose ESAs Found to Increase Cancer Risk in Dialysis Patients

High-Dose ESAs Found to Increase Cancer Risk in Dialysis Patients

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Average weekly doses greater than 70 µg/week was associated with a 77% increased risk of cancer compared with no ESA exposure.

ESA-Resistance Linked to Early Death

ESA-Resistance Linked to Early Death

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A high erythropoietin resistance index was associated with triple the risk for death from any cause.

Is Giving Small Iron Doses Per Dialysis Session Better for Patients?

Is Giving Small Iron Doses Per Dialysis Session Better for Patients?

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Patients provided small doses of intravenous iron per treatment achieved higher hemoglobin levels than patients receiving weekly iron.

Hepatic Iron Overload May Be Common Before Dialysis

Hepatic Iron Overload May Be Common Before Dialysis

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In a small study, 82% of patients had iron overload prior to hemodialysis initiation.

Anemia Prevalence, Treatment in Non-Dialysis CKD Varies by Country

Anemia Prevalence, Treatment in Non-Dialysis CKD Varies by Country

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Less than half of anemic patients were prescribed ESAs or iron in the US and France, and a high percentage overall did not have iron indices measured.

ESA Doses Lower Among Dialysis Patients at Higher Elevations

ESA Doses Lower Among Dialysis Patients at Higher Elevations

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Investigators find that the normalized mean ESA dose decreases as patients' elevation of residence increases.

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