Anemia

ESA Doses Lower Among Dialysis Patients at Higher Elevations

ESA Doses Lower Among Dialysis Patients at Higher Elevations

By

Investigators find that the normalized mean ESA dose decreases as patients' elevation of residence increases.

Higher Conversion Ratio for Epoetin Beta to Darbepoetin Alfa

Higher Conversion Ratio for Epoetin Beta to Darbepoetin Alfa

By

Researchers confirmed higher dose conversion ratios in Taiwanese patients with stable hemoglobin.

Anemia Risk Factors in Peritoneal Dialysis Patients ID'd

Anemia Risk Factors in Peritoneal Dialysis Patients ID'd

By

New findings implicate transferrin saturation and nutritional status assessed by albumin.

TRT Found to Reduce Anemia in Hypogonadal Men

TRT Found to Reduce Anemia in Hypogonadal Men

By

After 54 weeks of treatment with testosterone undecanoate, anemia prevalence decreased from 29.6% to 10%.

Managing Anemia in Cancer Patients With CKD

Managing Anemia in Cancer Patients With CKD

A summary of Dr. Jeffrey S. Berns' presentation that will be given at the National Kidney Foundation's 2016 Spring Clinical Meetings in Boston, MA.

Ferritin Levels Rising in Hemodialysis Patients

Ferritin Levels Rising in Hemodialysis Patients

By

Trend is independent of intravenous iron use and exposure to erythropoiesis-stimulating agents.

CERA Safe, Effective in Patient Subgroups

CERA Safe, Effective in Patient Subgroups

By

No new adverse events observed in patients with underlying cardiovascular risk factors who switched to continuous erythropoietin receptor activator.

Platelet/Lymphocyte Ratio May Predict ESA Resistance

Platelet/Lymphocyte Ratio May Predict ESA Resistance

By

Greater hyporesponsiveness to erythropoiesis-stimulating agents was associated with increased PLR ratios.

Dialysis Bundling, ESA Labeling Changes Did Not Increase Mortality

Dialysis Bundling, ESA Labeling Changes Did Not Increase Mortality

By

Observed rates of all-cause and cardiovascular mortality and myocardial infarction were consistent with expected rates, study shows.

Good Residual Renal Function Improves HD Patient Outcomes

Good Residual Renal Function Improves HD Patient Outcomes

By

Researchers observe significantly higher levels of albumin and hemoglobin and better calcium and phosphate metabolism.

ESAs Don't Improve Anemia Patients' Quality of Life

ESAs Don't Improve Anemia Patients' Quality of Life

Based on effect of erythropoietin-stimulating agents for higher hemoglobin targets.

ESRD Anemia Responds to Investigational Oral Drug

ESRD Anemia Responds to Investigational Oral Drug

By

In a phase 2 trial, roxadustat maintained hemoglobin levels over 19 weeks as well as epoetin alfa.

IV Iron Safe for Treating Anemia in Acute Kidney Injury Patients

IV Iron Safe for Treating Anemia in Acute Kidney Injury Patients

By

In a case-control study, the treatment did not adversely affect mortality or recovery from AKI.

Earlier ESA Initiation May Improve Renal Outcomes

Earlier ESA Initiation May Improve Renal Outcomes

By

Study shows benefit of initiating epoetin beta therapy at hemoglobin levels not less than 10 g/dL in non-dialysis CKD patients.

Recombinant Erythropoietin Benefits Non-Dialysis CKD Patients

Recombinant Erythropoietin Benefits Non-Dialysis CKD Patients

By

Treatment corrects anemia and improves quality of life, according to a systemic review.

Ergocalciferol Supplements Improve Vitamin D Deficiency, Not Anemia

Ergocalciferol Supplements Improve Vitamin D Deficiency, Not Anemia

Six-months of supplementation has no impact on epoetin utilization in HD patients with low 25(OH)D.

Hemoglobin Levels May Discriminate CKD Stages in the Elderly

Hemoglobin Levels May Discriminate CKD Stages in the Elderly

By

In a study, investigators observed that levels were higher in those with stage 3a than stage 3b chronic kidney disease.

Weekly ESA Dosing at Dialysis Centers May Offer Time Savings

Weekly ESA Dosing at Dialysis Centers May Offer Time Savings

By

The estimated potential staff time savings totaled 23 hours for an average facility with 70 patients, researchers found.

Ferumoxytol Similar in Safety to Other IV Iron Products

Ferumoxytol Similar in Safety to Other IV Iron Products

By

Rates of death and important non-fatal outcomes between ferumoxytol and iron sucrose or sodium ferric gluconate do not differ significantly.

Transfusion, Mortality Link Varies With Hemoglobin, Heart Disease

Transfusion, Mortality Link Varies With Hemoglobin, Heart Disease

For ICU patients, hemoglobin level thresholds vary with presence of comorbid heart disease.

Anaphylaxis Risk Among IV Iron Products Ranked

Anaphylaxis Risk Among IV Iron Products Ranked

Risk of anaphylaxis associated with IV iron highest for iron dextran, lowest for iron sucrose.

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

Lower Pre-ESRD Hemoglobin Predicts Better Dialysis Patient Survival

By

Having hemoglobin 9-11 g/dL prior to dialysis provided the best life expectancy.

Red Cell Distribution Width Linked With Mortality in Dialysis

Red Cell Distribution Width Linked With Mortality in Dialysis

By

It is unclear whether RDW is a risk factor for early death or a byproduct of biological and metabolic imbalances.

Statins May Improve Response to Erythropoiesis-Stimulating Agents

Statins May Improve Response to Erythropoiesis-Stimulating Agents

By

Patients prescribed the lipid-lowering agents were less likely to exhibit hyporesponsiveness to the medications.

Erythropoietin Resistance More Likely in Female Dialysis Patients

Erythropoietin Resistance More Likely in Female Dialysis Patients

By

Study finds no gender differences in parathyroid hormone, ferritin, Kt/V, or age.

Vitamin C Found to Decrease Erythropoietin Requirement

Vitamin C Found to Decrease Erythropoietin Requirement

By

In a study, the mean hemoglobin level increased significantly in hemodialysis patients with functional iron deficiency.

Iron Deficiency Ups Mortality in Renal Transplant Recipients

Iron Deficiency Ups Mortality in Renal Transplant Recipients

By

The association is independent of anemia, according to researchers.

Anemia More Severe in Hemodialysis Patients with PEW

Anemia More Severe in Hemodialysis Patients with PEW

By

Patients with vs. without protein-energy wasting syndrome had a significantly lower mean hemoglobin level.

HCV Ups Anemia-Related Event Risks in Hemodialysis Patients

HCV Ups Anemia-Related Event Risks in Hemodialysis Patients

By

Hepatitis C viral infection found to increase likelihood of requiring blood transfusions and hemoglobin levels dropping below 8.5 g/dL.

Iron Deficiency Linked With Elevated FGF-23 in Pediatric CKD

Iron Deficiency Linked With Elevated FGF-23 in Pediatric CKD

By

Iron deficiency may contribute to the relationship between proteinuria and excess FGF-23, researchers suggested.

Sign Up for Free e-newsletters