Acute Kidney Injury
Though hospital admission rates have increased, inpatient death has improved from 2003 to 2012.
Among patients admitted to a coronary care unit, the highest quartile of serum cystatin C levels was associated with a 9.6-fold increased risk of AKI compared with the lowest quartile.
Dabigatran and rivaroxaban were associated with lower risks of adverse renal outcomes compared with warfarin.
In a study of hospitalized US veterans, AKI was associated with a 23% increased risk of heart failure compared with the absence of AKI.
The model was based on 6 variables readily obtained at hospital discharge.
Contrast-associated acute kidney injury occurred in 9.5% and 9.1% of patients receiving IV sodium bicarbonate and acetylcysteine, respectively, rates which did not differ significantly from the 8.3% rate among those receiving IV sodium chloride.
From 2004 to 2012, the incidence of AKI increased from 4.9% to 14.2% among CABG patients and from 2.7% to 8.8% among PCI patients.
In a phase 3 trial, acute kidney injury developed in 13.2% of patients undergoing invasive coronary angiography compared with 5.6% of those undergoing computed tomography angiography.
In a study, end-stage renal disease developed in 56% of patients discharged from a hospital with acute kidney injury requiring dialysis.
Timing of AKI after urgent percutaneous coronary intervention affects risk of significant kidney function loss 1 year after the procedure.
Post hoc analysis of SPRINT finds no significant difference in the incidence of fatal and nonfatal cardiovascular events among patients with moderate-to-advanced chronic kidney disease.
In a study, AKI sufferers had an increased rate of venous thromboembolism whether they receive heparin prophylaxis or not.
Three-quarters of patients hospitalized with acute kidney injury in Alberta, Canada did not visit a kidney specialist within 12 months of discharge.
Elevated levels of the two proteins can predict risk of acute kidney injury.
Risk of AKI in hospitalized children higher than with IV vancomycin, other antipseudomonal -lactam
AKI occurred with similar frequency among patients who did and did not receive contrast medium.
Findings do not suggest an increased risk of AKI associated with SGLT2 inhibitor use in patients with type 2 diabetes.
Higher mortality was seen in association with an emergency department discharge with acute kidney injury vs no acute kidney injury.
Myocardial infarction patients who underwent percutaneous coronary intervention had an AKI rate similar to those who did not have the procedure.
Evidence to date provides no clear answer as to whether early or delayed RRT is the best approach.
Chronic kidney disease and anemia are associated with an increased risk for acute kidney injury in patients with pulmonary embolism.
Of the children who developed acute kidney injury, 34.9% had stage 1, 45.3% had stage 2, and 19.8% had stage 3.
An increase in injury and repair biomarker levels suggests structural damage to renal tubules occurring after marathon.
Proton pump inhibitors need not first cause acute kidney injury for CKD risk to be elevated.
Compared with control treatment, RenalGuard therapy correlated with significantly reduced CI-AKI, as well as a reduced need for renal replacement therapy.
Patients with an eGFR below 60 mL/min/1.73 m2 were more likely to die in the hospital or be discharged to hospice.
There is a strong association between magnified nadir platelet counts and the severity of AKI.
Women with r-AKI had increased rates of preeclampsia and premature infant births, compared with controls.
The researchers found that stage 2 acute kidney injury was associated with increased risk of delirium and coma as was stage 3 acute kidney injury.
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)