Acute Kidney Injury
Sodium bicarbonate infusions decreased the risk of death or organ failure among ICU patients with acute kidney injury and severe metabolic acidemia.
Proteinuria at the time of surgery is associated with an elevated risk of postoperative acute kidney injury and 30-day unplanned readmission.
Reduced kidney injury, better kidney function seen after prolonged cardiopulmonary bypass.
According to the authors, this is the first study to identify medications most commonly reported for a specific adverse reaction using the FAERS database.
For hospitalized patients, risk also increased for those receiving 3 or more CNS antidepressants.
If the study findings are confirmed, earlier detection of heart failure could save lives, according to researchers.
Early acetaminophen exposure after pediatric cardiac surgery may reduce rate of acute kidney injury.
Fluid restriction has no impact on disability-free survival; increases risk of acute kidney injury
Cystatin C as biomarker, kidney function marker linked to 20-year cumulative incidence of HI.
Investigators report that female vs male sex was associated with a significant 14% lower mortality risk following an episode of community-acquired acute kidney injury.
In the most comprehensive study of its kind, investigators find that acute kidney injury not requiring hospitalization is associated with a 90% increased mortality risk.
In a large study, caffeine administration to neonates born before 33 weeks' gestation reduced their odds of experiencing AKI by a significant 80%.
AKI hospitalizations were 4 times more likely among patients with diabetes.
Balanced crystalloids decreases adverse kidney events compared to saline among critically ill patients: The SMART trialMarch 07, 2018
1. Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared to normal saline among intensive care unit (ICU) patients. 2. Use of balanced crystalloids was also associated with lower though nonsignificant in-hospital mortality at 30-days after admission. Evidence Rating Level: 1 (Excellent) Study 
No patient had a 25% or greater rise in serum creatinine 48 hours after receiving a median 13 mL of contrast for diagnostic coronary angiography, with an additional 13 mL for percutaneous coronary intervention.
AKI associated with 27% increased risk of hypoglycemia among patients with diabetes.
High risk of AKI in first year after non-kidney solid organ transplant; in turn, increases CKD risk.
Early and late initiation of renal replacement therapy for AKI in critically ill patients are associated with similar long-term risks of death, chronic kidney disease, and end-stage renal disease.
Though hospital admission rates have increased, inpatient death has improved from 2003 to 2012.
Among patients admitted to a coronary care unit, the highest quartile of serum cystatin C levels was associated with a 9.6-fold increased risk of AKI compared with the lowest quartile.
Dabigatran and rivaroxaban were associated with lower risks of adverse renal outcomes compared with warfarin.
In a study of hospitalized US veterans, AKI was associated with a 23% increased risk of heart failure compared with the absence of AKI.
The model was based on 6 variables readily obtained at hospital discharge.
Contrast-associated acute kidney injury occurred in 9.5% and 9.1% of patients receiving IV sodium bicarbonate and acetylcysteine, respectively, rates which did not differ significantly from the 8.3% rate among those receiving IV sodium chloride.
From 2004 to 2012, the incidence of AKI increased from 4.9% to 14.2% among CABG patients and from 2.7% to 8.8% among PCI patients.
In a phase 3 trial, acute kidney injury developed in 13.2% of patients undergoing invasive coronary angiography compared with 5.6% of those undergoing computed tomography angiography.
In a study, end-stage renal disease developed in 56% of patients discharged from a hospital with acute kidney injury requiring dialysis.
Timing of AKI after urgent percutaneous coronary intervention affects risk of significant kidney function loss 1 year after the procedure.
Post hoc analysis of SPRINT finds no significant difference in the incidence of fatal and nonfatal cardiovascular events among patients with moderate-to-advanced chronic kidney disease.
In a study, AKI sufferers had an increased rate of venous thromboembolism whether they receive heparin prophylaxis or not.
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)