Acute Kidney Injury

AKI With <i>C. difficile</i> Admissions Increasing

AKI With C. difficile Admissions Increasing

Though hospital admission rates have increased, inpatient death has improved from 2003 to 2012.

Acute Kidney Injury in CCU Patients Linked to Cystatin C

Acute Kidney Injury in CCU Patients Linked to Cystatin C

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Among patients admitted to a coronary care unit, the highest quartile of serum cystatin C levels was associated with a 9.6-fold increased risk of AKI compared with the lowest quartile.

Kidney Risks Differ Among Oral Anticoagulant Drugs for AFib

Kidney Risks Differ Among Oral Anticoagulant Drugs for AFib

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Dabigatran and rivaroxaban were associated with lower risks of adverse renal outcomes compared with warfarin.

Acute Kidney Injury Predicts Heart Failure

Acute Kidney Injury Predicts Heart Failure

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In a study of hospitalized US veterans, AKI was associated with a 23% increased risk of heart failure compared with the absence of AKI.

New Model Improves Predictions of Advanced CKD Following AKI

New Model Improves Predictions of Advanced CKD Following AKI

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The model was based on 6 variables readily obtained at hospital discharge.

IV Sodium Bicarbonate Does Not Reduce AKI Risk After Angiography

IV Sodium Bicarbonate Does Not Reduce AKI Risk After Angiography

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Contrast-associated acute kidney injury occurred in 9.5% and 9.1% of patients receiving IV sodium bicarbonate and acetylcysteine, respectively, rates which did not differ significantly from the 8.3% rate among those receiving IV sodium chloride.

Acute Kidney Injury After Cardiac Revascularization on the Rise

Acute Kidney Injury After Cardiac Revascularization on the Rise

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From 2004 to 2012, the incidence of AKI increased from 4.9% to 14.2% among CABG patients and from 2.7% to 8.8% among PCI patients.

AKI More Likely After Intracoronary Versus IV Contrast Delivery

AKI More Likely After Intracoronary Versus IV Contrast Delivery

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In a phase 3 trial, acute kidney injury developed in 13.2% of patients undergoing invasive coronary angiography compared with 5.6% of those undergoing computed tomography angiography.

ESRD Frequently Follows Dialysis-Dependent AKI

ESRD Frequently Follows Dialysis-Dependent AKI

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In a study, end-stage renal disease developed in 56% of patients discharged from a hospital with acute kidney injury requiring dialysis.

AKI at 12 and 24 Hours After PCI Independently Ups Death Risk

AKI at 12 and 24 Hours After PCI Independently Ups Death Risk

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Timing of AKI after urgent percutaneous coronary intervention affects risk of significant kidney function loss 1 year after the procedure.

Intensive Blood Pressure Control May Not Benefit CKD Patients

Intensive Blood Pressure Control May Not Benefit CKD Patients

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Post hoc analysis of SPRINT finds no significant difference in the incidence of fatal and nonfatal cardiovascular events among patients with moderate-to-advanced chronic kidney disease.

VTE Prophylaxis Inadequate for Acute Kidney Injury Patients

VTE Prophylaxis Inadequate for Acute Kidney Injury Patients

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In a study, AKI sufferers had an increased rate of venous thromboembolism whether they receive heparin prophylaxis or not.

Acute Kidney Injury Follow-up Falls Short

Acute Kidney Injury Follow-up Falls Short

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Three-quarters of patients hospitalized with acute kidney injury in Alberta, Canada did not visit a kidney specialist within 12 months of discharge.

Urinary Biomarker May Predict AKI After Heart Surgery

Urinary Biomarker May Predict AKI After Heart Surgery

Elevated levels of the two proteins can predict risk of acute kidney injury.

Vancomycin, Piperacillin/Tazobactam Combo Ups AKI in Kids

Vancomycin, Piperacillin/Tazobactam Combo Ups AKI in Kids

Risk of AKI in hospitalized children higher than with IV vancomycin, other antipseudomonal -lactam

AKI After Computed Tomography Not Tied to Contrast

AKI After Computed Tomography Not Tied to Contrast

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AKI occurred with similar frequency among patients who did and did not receive contrast medium.

AKI Risks Not Up With SGLT2 Inhibitors

AKI Risks Not Up With SGLT2 Inhibitors

Findings do not suggest an increased risk of AKI associated with SGLT2 inhibitor use in patients with type 2 diabetes.

Mortality Up for ER Patients Discharged With AKI

Mortality Up for ER Patients Discharged With AKI

Higher mortality was seen in association with an emergency department discharge with acute kidney injury vs no acute kidney injury.

Post-PCI Acute Kidney Injury Not Linked to Contrast Use

Post-PCI Acute Kidney Injury Not Linked to Contrast Use

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Myocardial infarction patients who underwent percutaneous coronary intervention had an AKI rate similar to those who did not have the procedure.

Timing of Renal Replacement Therapy Initiation in AKI

Timing of Renal Replacement Therapy Initiation in AKI

Evidence to date provides no clear answer as to whether early or delayed RRT is the best approach.

AKI Predictors in PE Patients Identified

AKI Predictors in PE Patients Identified

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Chronic kidney disease and anemia are associated with an increased risk for acute kidney injury in patients with pulmonary embolism.

Children With Diabetic Ketoacidosis at High Risk of AKI

Children With Diabetic Ketoacidosis at High Risk of AKI

Of the children who developed acute kidney injury, 34.9% had stage 1, 45.3% had stage 2, and 19.8% had stage 3.

Marathon Runners May Develop AKI, Tubular Injury

Marathon Runners May Develop AKI, Tubular Injury

An increase in injury and repair biomarker levels suggests structural damage to renal tubules occurring after marathon.

Chronic Kidney Disease More Likely in PPI Users

Chronic Kidney Disease More Likely in PPI Users

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Proton pump inhibitors need not first cause acute kidney injury for CKD risk to be elevated.

Furosemide With Matched Hydration Prevents Contrast Nephropathy

Furosemide With Matched Hydration Prevents Contrast Nephropathy

Compared with control treatment, RenalGuard therapy correlated with significantly reduced CI-AKI, as well as a reduced need for renal replacement therapy.

Kidney Function Predicts Hospital Discharge, Mortality After Stroke

Kidney Function Predicts Hospital Discharge, Mortality After Stroke

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Patients with an eGFR below 60 mL/min/1.73 m2 were more likely to die in the hospital or be discharged to hospice.

Platelet Counts Linked to AKI Severity in Pediatric Open-Heart Surgery

Platelet Counts Linked to AKI Severity in Pediatric Open-Heart Surgery

There is a strong association between magnified nadir platelet counts and the severity of AKI.

Previous AKI Episode Associated With Pregnancy Risks

Previous AKI Episode Associated With Pregnancy Risks

Women with r-AKI had increased rates of preeclampsia and premature infant births, compared with controls.

AKI Is a Risk Factor for Delirium, Coma in Critically Ill

AKI Is a Risk Factor for Delirium, Coma in Critically Ill

The researchers found that stage 2 acute kidney injury was associated with increased risk of delirium and coma as was stage 3 acute kidney injury.

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