Investigators are sounding a new warning about NSAIDs and acute kidney injury in children.
Severe acute kidney injuries have been rising rapidly in the United States over the past 10 years.
The incidence of AKI requiring dialysis is now higher than the incidence of ESRD requiring dialysis or transplant.
Increased rate of acute kidney injury observed with the use of gentamicin plus flucloxacillin after othropedic surgery.
GI, kidney, and cardiovascular adverse events may increase with analgesic dose
Initiating use prior to coronary artery bypass grafting surgery may modestly reduce risks.
Contrast volume:eGFR ratio may be useful in calculating the maximum amount of contrast to give.
The absolute risk is small, but data may make a case for the use of low-potency statins when possible.
Acute kidney injury also increases their risk of death.
Sixteen cases of acute kidney injury occurred in six states.
In a study, it accounted for 2.7% of AKI cases.
Excessive body fat on CT scans is associated with an elevated risk of acute kidney injury.
These include hypovolemia, diuretic use, and CKD prior to admission.
Urine output may provide a better indication of renal function, according to researchers.
Reasons include better hemodynamic stability, better therapeutic effect, and easier fluid balance control.
Risk up with use of diuretic and ACE inhibitor or angiotensin receptor blocker, plus NSAID.
Obstructive uropathy is rarely found to be a cause of acute kidney injury.
New findings underscore the need for continued improvement in the recognition and management of patients with AKI.