PSA density is strongly associated with pathological stage and biochemical-free survival after radical prostatectomy for prostate cancer, researchers conclude.

Black men may be getting the message that they are at increased risk of prostate cancer, according to a study published in Cancer Epidemiology, Biomarkers & Prevention (2008;17:636-644).

GRAY-SCALE transrectal ultrasonography (TRUS) alone has a limited potential to detect prostate cancer, particularly in patients with total PSA levels below 20 ng/mL, researchers reported in the Journal of Medical Imaging and Radiation Oncology (2008;52:24-28).

DELAYED CLINICIAN response to a patient's abnormal PSA level occurs in about 23% of cases, which may be more common than generally appreciated, according to researchers.

Grey-scale transrectal ultrasonography (TRUS) alone has a limited potential to detect prostate cancer, particularly in patients with total PSA levels below 20 ng/mL, researchers reported in the Journal of Medical Imaging and Radiation Oncology (2008;52:24-28).

HEMODILUTION from increased circulating plasma volumes could explain why obese men with prostate cancer have lower serum PSA levels than non-obese men with the malignancy, according to researchers.

Using an assay they developed to detect antibodies to Propionibacterium acnes bacteria, researchers have found a link between these bacteria and development of inflammation-related prostate diseases.

Hemodilution from increased circulating plasma volumes could explain why obese men with prostate cancer have lower serum PSA levels than non-obese men with the malignancy, according to researchers.

PSA density is an independent determinant of PSA velocity in untreated localized prostate cancer, a study in the UK concluded.

CHICAGO – A new compound that specifically inhibits production of the cell-survival protein clusterin appears to be well tolerated and produces PSA responses when given in combination with docetaxel and prednisone in men with metastatic hormone refractory prostate cancer (HRPC), a study found.