The renin-angiotensin-aldosterone system (RAAS) is a well-known regulator of BP, and angiotensin II (AII) plays the primary role in constricting the postglomerular arterioles. This increases both the glomerular hydraulic pressure and the ultrafiltration of plasma proteinseffects that may con- tribute to chronic renal damage. AII may stimulate renal cell growth, inflammation, and fibrosis.